Introduction: Physical contact is important in all human culture. Individuals can express different emotions in order to seek or offer physical support. Norepinephrine is one of the stress hormones, and is a part of the sympathetic nervous system, which can mediate anxiety and acute stress response. The level of norepinephrine during stress while holding someone´s hand is still underestimated. Aim: is to investigate the release of norepinephrine while getting touched once by a romantic partner and once by an unfamiliar stranger with the hypothesis that norepinephrine level would be greater while getting stroked by a stranger comparing to the partner.Method: 3 cat ELISA for the quantitative determination of norepinephrine from ImmuSmol. The data were analyzed with SPSS, non-parametrical Man Whitney-U test was carried out to do group wise comparison and time points comparison was done by Kruskal Wallis. Additionally, Spearman´s Correlation was conducted to compare norepinephrine correlation with other hormones like cortisol, oxytocin, and epinephrine. Result: no significant result have shown by comparing groups and by doing timepoints comparison. Spearman´s correlation have not shown a significant association between norepinephrine and other hormones. Conclusion: gentle touches whether it was from stranger or partner was not enough to elicit adifference in response. However, the original design aimed to focus on stimulating oxytocin and cortisol release. Thus, the design of the study should be changed for further investigation of the effect of social touches on norepinephrine.