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  • 10201.
    Yildirimman, Reha
    et al.
    Max Planck Inst Mol Genet, Dept Vertebrate Genom, D-14195 Berlin, Germany .
    Brolén, Gabriella
    Cellartis AB, SE-41346 Gothenburg, Sweden .
    Vilardell, Mireia
    Max Planck Inst Mol Genet, Dept Vertebrate Genom, D-14195 Berlin, Germany .
    Eriksson, Gustav
    Cellartis AB, SE-41346 Gothenburg, Sweden .
    Synnergren, Jane
    University of Skövde, School of Life Sciences.
    Gmuender, Hans
    Genedata AG, CH-4053 Basel, Switzerland .
    Kamburov, Atanas
    Max Planck Inst Mol Genet, Dept Vertebrate Genom, D-14195 Berlin, Germany .
    Ingelman-Sundberg, Magnus
    Karolinska Inst, Dept Physiol & Pharmacol, Pharmacogenet Sect, S-17177 Stockholm, Sweden .
    Castell, Jose
    Univ Valencia, Fac Med, Dept Biochem & Mol Biol, E-46009 Valencia, Spain / Univ Hosp La Fe Valencia, Unit Expt Hepatol, E-46009 Valencia, Spain .
    Lahoz, Agustin
    Univ Hosp La Fe Valencia, Unit Expt Hepatol, E-46009 Valencia, Spain .
    Kleinjans, Jos
    Maastricht Univ, Dept Toxicogen, NL-6229 ER Maastricht, Netherlands.
    van Delft, Joost
    Maastricht Univ, Dept Toxicogen, NL-6229 ER Maastricht, Netherlands.
    Bjorquist, Petter
    Cellartis AB, SE-41346 Gothenburg, Sweden .
    Herwig, Ralf
    Max Planck Inst Mol Genet, Dept Vertebrate Genom, D-14195 Berlin, Germany .
    Human Embryonic Stem Cell Derived Hepatocyte-Like Cells as a Tool for In Vitro Hazard Assessment of Chemical Carcinogenicity2011In: Toxicological Sciences, ISSN 1096-6080, E-ISSN 1096-0929, Vol. 124, no 2, p. 278-290Article in journal (Refereed)
    Abstract [en]

    Hepatocyte-like cells derived from the differentiation of human embryonic stem cells (hES-Hep) have potential to provide a human relevant in vitro test system in which to evaluate the carcinogenic hazard of chemicals. In this study, we have investigated this potential using a panel of 15 chemicals classified as noncarcinogens, genotoxic carcinogens, and nongenotoxic carcinogens and measured whole-genome transcriptome responses with gene expression microarrays. We applied an ANOVA model that identified 592 genes highly discriminative for the panel of chemicals. Supervised classification with these genes achieved a cross-validation accuracy of > 95%. Moreover, the expression of the response genes in hES-Hep was strongly correlated with that in human primary hepatocytes cultured in vitro. In order to infer mechanistic information on the consequences of chemical exposure in hES-Hep, we developed a computational method that measures the responses of biochemical pathways to the panel of treatments and showed that these responses were discriminative for the three toxicity classes and linked to carcinogenesis through p53, mitogen-activated protein kinases, and apoptosis pathway modules. It could further be shown that the discrimination of toxicity classes was improved when analyzing the microarray data at the pathway level. In summary, our results demonstrate, for the first time, the potential of human embryonic stem cell--derived hepatic cells as an in vitro model for hazard assessment of chemical carcinogenesis, although it should be noted that more compounds are needed to test the robustness of the assay.

  • 10202.
    Yngman-Uhlin, Pia
    et al.
    Linköping University, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping, Sweden / Department of Nephrology, University Hospital, Linköping, Sweden.
    Johansson, Anna
    Linköping University, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping, Sweden / Department of Cardiology, Skövde Hospital, Skövde, Sweden.
    Fernström, Anders
    Department of Nephrology, University Hospital, Linköping, Sweden.
    Börjeson, Sussanne
    Linköping University, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping, Sweden.
    Edéll-Gustafsson, Ulla
    Linköping University, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping, Sweden.
    Fragmented sleep: an unrevealed problem in peritoneal dialysis patients2011In: Scandinavian Journal of Urology and Nephrology, ISSN 0036-5599, E-ISSN 1651-2065, Vol. 45, no 3, p. 206-215Article in journal (Refereed)
    Abstract [en]

    OBJECTIVE: The aim of this study was to describe the sleep-wake cycle, sleep quality, fatigue and Health Related Quality of Life (HRQoL) measured with questionnaires, actigraphy and a sleep diary during a one-week period in patients undergoing peritoneal dialysis (PD) treatment at home. A further aim was to explore differences compared with patients with coronary artery disease (CAD) and individuals from the general population.

    MATERIAL AND METHODS: In this study one-week actigraphy registration, four questionnaires (Uppsala Sleep Inventory, SF-36, FACIT-fatigue, International Restless Legs Study Groups' form) and a sleep diary were used.

    RESULTS: Data from 68 participants and 470 nights were collected. PD patients (n = 28) had more fragmented sleep (p < 0.001) and worse sleep efficiency (SE%) (p < 0.0001) than the CAD (n = 22) and the population (n = 18) groups. Pruritus (57%), restless legs (46%) and fatigue (89%) were prevalent in PD patients. Pruritus correlated with fragmented sleep (r = -0.45, p = 0.01) and SE (r = -0.49, p = 0.01). In HRQoL, the physical component score was decreased in the PD and CAD groups (p < 0.01) compared to the population group.

    CONCLUSIONS: To the authors' knowledge this study is the first to demonstrate that PD patients have deteriorated sleep, with serious fragmentation measured by a one-week actigraphy registration. Further, PD patients exhibit worse sleep quality than CAD patients and individuals in the population. Evaluation of sleep in clinical practice is highly recommended since PD patients are vulnerable individuals with extended self-care responsibilities and at risk for comorbidity secondary to insufficient sleep. Future research on whether PD patients' sleep problems and fatigue can be improved by an individual non-pharmacological intervention programme is required.

  • 10203.
    Yngve, Sara
    University of Skövde, School of Bioscience.
    Optimization of PCR Sensitivity for Detection of Bacterial Species in Blood of Patients with Suspected Sepsis2015Independent thesis Advanced level (degree of Master (One Year)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    Sepsis is commonly caused by bacteria, fungi or both present in the blood stream during inflammation. In response, inflammatory cascades are released in multiple organ systems which if prolonged causes sepsis and can eventually lead to organ failure and death. The major diagnostic technique of sepsis is blood culturing. However, the technique is time consuming and lacks sensitivity; especially in patients under antimicrobial therapy. Molecular techniques particularly PCR could possibly become implemented in sepsis diagnostics in the future. The aim of the thesis was to compare the effect on PCR sensitivity by different PCR kits, with optimized PCR conditions to find an ideal Real-time PCR applicable for direct detection of rRNA or rDNA in whole blood, using the 16S rDNA gene. The study also surveyed the overall background flora of bacterial species circulating in the blood. During the optimization Haemophillus influenzae and Streptococcus pneumoniae were added to whole blood, rRNA or rDNA was isolated and extracted and subsequently processed by Real-time PCR. Four commercially available PCR kits were compared. Attempts using rRNA did not significantly increase the PCR sensitivity. LightCycler FastStart DNA Master SYBR Green I kit (Roche Diagnostics) used for rDNA, generated low cp-values, the cleanest sequences and the finest separation between amplification curves. Twenty whole blood and pre-cultured patient samples were processed by the optimized PCR. The effect on PCR sensitivity by pre-culturing patient blood samples was studied and no statistical difference was noted. Increased PCR sensitivity is essential for implementation of PCR techniques in sepsis diagnostics.

  • 10204.
    Yngve, Simon
    University of Skövde, School of Humanities and Informatics.
    Evolutionär algoritm för schemaläggning av kontinuerligt skiftarbete: Schemaläggning med ergonomiska riktlinjer2010Independent thesis Basic level (degree of Bachelor), 20 credits / 30 HE creditsStudent thesis
    Abstract [sv]

    Många organisationer har ett behov av bemanning hela dygnet alla dagar i veckan. Personal vid sådana organisationer organiseras i arbetslag som enligt ett arbetsschema löser av varandra under dygnets gång. Beroende på hur dessa arbetsscheman utformas kan de få en negativ inverkan på personalens hälsa. Den här rapporten handlar om utvecklandet av en algoritm som genererar arbetsscheman med ergonomiska riktlinjer, det vill säga arbetsscheman som utformats på ett sådant sätt att negativa effekter på personalens hälsa undviks. Algoritmen som utvecklas baseras på optimeringsalgoritmen Squeaky Wheel Optimization. Resultatet av arbetet visar att arbetsscheman som genererats av algoritmen är av sådan hög kvalité att de skulle kunna appliceras praktiskt hos en organisation som har ett bemanningsbehov hela dygnet alla dagar i veckan. Tack vare algoritmens generella karaktär kan algoritmen användas som ett verktyg för schemagenerering hos en stor mängd företag.

  • 10205.
    Yngvesson, Anna
    et al.
    University of Skövde, School of Informatics.
    Levander, Maria
    University of Skövde, School of Informatics.
    Representation av transpersoner i spelsammanhang: En studie om HBTQ-personers upplevelse av transkaraktärer2019Independent thesis Basic level (degree of Bachelor), 20 credits / 30 HE creditsStudent thesis
    Abstract [sv]

    Det råder en brist på transkaraktärer i spel och dessa efterfrågas ständigt av transpersoner. I denna studie har vi skapat 5 transkaraktärer med både grafisk gestaltning och exempelscen från det påhittade spelet för varje karaktär. Dessa visades sedan för 6 respondenter som identifierar sig inom HBTQ-spektrumet och deltagarnas uppfattning om karaktärerna diskuterades. Resultatet visar att samtliga karaktärer utom en ansågs vara positiv representation i spel, då dessa inte fokuserar på negativa stereotyper som transpersoner får utstå. Som slutsats kan vi konstatera att så länge karaktärerna behandlas med respekt vill respondenterna främst ha fler karaktärer, oavsett personlighet och utseende. Det finns dock vissa aspekter i skapandet av transkaraktärer som bör tänkas över, då de kan påverka synen på transpersoner negativt, men som respondenterna ponerade kan vara gynnande för transpersoner själva att se i spel. Det blir alltså en balansgång över vad som transpersoner själva vill se och vad som transfober kan använda som argument mot den marginaliserade gruppen.

  • 10206.
    Younan, Karam
    University of Skövde, School of Informatics.
    Smarttelefonsäkerhet: En studie kring studenters användning av inbyggda säkerhetsfunktioner i smarta telefoner2016Independent thesis Basic level (degree of Bachelor), 15 credits / 22,5 HE creditsStudent thesis
    Abstract [en]

    Smartphones combine telephony services with data services in a single device. In 2007, Apple released a new generation of phones run by iOS operating system, called iPhones. Android phones were developed by Google and were released the following year. Smartphones use has increased a lot and they have become one of the most common devices that are being used in most of companies nowadays. The concept BYOD stands for Bring Your Own Device, means that employees may use their own smartphones at work. This makes using the built-in security features in smartphones particularly important, not only to protect employees’ private information but also to protect their corporate information. Early research has shown that threats and attacks have also increased on smartphones. Hackers have focused their attacks on smartphones more than before. And have created mobile-based viruses, malware and spyware that target vulnerable smartphones. Smartphone users nowadays do not have much control of their smartphones security according to previous researches. However, smartphones manufacturers constantly add new built-in security features with each new version of operating system to protect them from various threats. Smartphone manufacturers may use the acquired final data to improve their products’ security and increase the use of mobile built-in security features.

    The current study researches students’ interaction and use of the built-in security features available in smartphones run by both Android and iOS operating systems. The study does not divide students into smaller groups; it rather focuses on all students as one group. Although this study was conducted in the University of Skovde in Sweden, its conclusion can be applied to a bigger population regardless of location. Today's students are tomorrow’s employees and managers who will have the responsibility to protect their companies’ proprietary and sensitive information. Therefore, it is critical that they understand and implement all up-to-date procedures to protect their smartphones and their companies.

    A quantitative study is conducted through a survey in order to reach as many participants as possible. Lime Survey tool is utilized to create surveys and to gather data. Statistics and diagrams are also used to demonstrate results to readers. A total of 201 participants completed the entire study, 134 participants answered the Android survey and 67 answered the iOS survey.

    The current survey results have shown, through a model that converts participants’ answers into a flow chart, that the use of the built-in security features varies among participating students. The use of these built-in security features was low in general. More than half of all participants do not use certain functions at all. The general low use of the built-in security features can be attributed to many reasons. This survey showed that the main reason of that was the lack of participants’ knowledge of these built-in security features. Several solutions exist for this lack of knowledge of participants, but they do not fall within the scope of this study therefore not discussed herein.

  • 10207.
    Younan Slewa, Ninos
    University of Skövde, School of Informatics.
    Säkerhetsutmaningar med metadatahantering: Utmaningar med insamlingen av personlig metadata via e-handelssystem2017Independent thesis Basic level (degree of Bachelor), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    The development and progress of the e-commerce system has dominated electronic trade in recent years. Problems that often arise are how confident is the handling of consumer data, specifically regarding the personal metadata that the user generates when shopping through the net. Many companies and organizations are investing a great deal in expanding their consumer services using market strategy Business-to-Consumer (B2C), but most collecting data have little attention to consistent documents that occur with the management of personal privacy, collection of personal metadata and the legal protection of this type of data. This paper addresses challenges with how personal metadata is handled and how it can be implemented to make the use less problematic. Survey in this paper found that the challenge lies mostly in the coordination between technology and law. IT experts must specify how metadata should be collected, how it should be stored and what should it be used for, while legal experts must qualify if metadata is to be treated as traditional data or whether it will have a specific legal system. Other findings such as the collection, storage and usage of metadata were also featured in this work.

  • 10208. Young, S
    et al.
    Ejdebäck, Mikael
    Göteborgs universitet.
    Sigfridsson, K
    Samuelson, A
    Hansson, Örjan
    Spectroscopic and kinetic characterization of site-specific mutants of plastocyanin1995In: Photosynthesis: From Light To Biosphere, Vol. 2 / [ed] Mathis, P., Dordrecht: Kluwer Academic Publishers, 1995, p. 669-672Conference paper (Other academic)
  • 10209.
    Yu, Jesper
    et al.
    University of Skövde, School of Technology and Society.
    Karlsson, Daniel
    University of Skövde, School of Technology and Society.
    Conceptual mobile device with focus on design for recycling2011Independent thesis Basic level (degree of Bachelor), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    One of the largest product categories within all the electronic products is portable ­computers, also known as notebooks, is slowly replacing stationary computers and is ­predicted to be the mainstream choice in the near future. But the current state of ­notebook shows these products are not accommodated for an effective large scale ­recycling process. As the notebooks are becoming more compact, its inner ­structures have become more complicated. Permanently fastening methods, multi-material ­compositions and many other factors contribute to an ineffective, expensive and tedious recycling process.

    The goal of the project treated in this report was to investigate the possibilities of a simplified structure adapted for an effective disassembly and recycling process. And to develop a conceptual notebook adapted for the stated purpose.

    The project resulted in a conceptual notebook named Sixten with an enhanced and ­simplified inner structure. All permanently fastening methods was replaced by ­detachable locking and securing devices. The number of tools required for dismantling was reduced, as the usage of screws. The variation of materials used in the notebook, with ­electrical components apart, is low. These materials, ABS plastics and aluminum were chosen based on their recyclable and processing possibilities. But also because of the durability and desired mechanical properties the structure required. The limited number of materials used in Sixten makes it environmentally beneficial since every material ­requires its own specific recycling process, and by reducing the number of materials energy can be saved on using only a few recycling methods.

    Sixten fulfills the principals of design for disassembly as a notebook that is easy to ­disassemble in comparison with notebooks on the market today. The disassembly time has been reduced, from the 45 minutes which may be required to fully disassemble a conventional notebook, down to an estimated disassembly time of 6 minutes, which is the time Sixten requires. It is in this short disassembly time where the economic benefits of Sixten lie.

  • 10210.
    Yue, Xiabin
    et al.
    University of Skövde, School of Technology and Society.
    Xing, Bo
    University of Skövde, School of Technology and Society.
    The impact of R&D intensity on the volatility of stock price: A study of the Swedish Market during year 1997-20052007Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    This thesis investigates the theoretical and empirical relationships between a firm’s R&D investment intensity and the systematic risk of its common stock in Sweden. This is done by examining 38 Swedish firms between 1997 and 2005. An overlapping set of 5-year window is chosen to apply to calculate the variables of the samples.

    In this thesis, three factors are introduced as a proxy of main constituents of systematic risk: intrinsic business risk, degree of financial leverage and degree of operating leverage. And we use these three constituents to analysis the relationship between R&D investment and systematic risk.

    The results from Monte Carlos simulations and correlation analysis of our sample show that, in Sweden, firms with higher R&D intensity do face higher stock price volatility in the stock market. At the same time, we attempt to test the relationship among R&D and systematic risk’s three constituents, but find that R&D intensive firms have more financial leverage which is opposite to our expect, which might due to the shortage of data and limitation of our sample selection, and R&D intensive firms do not have obvious relations directly with intrinsic business risk, degree of financial leverage or degree of operating leverage.

  • 10211.
    Yüksel, Caroline
    et al.
    University of Skövde, School of Humanities and Informatics.
    Nilsson, Therese
    University of Skövde, School of Humanities and Informatics.
    Mobbning: - Förväntningar på skolan ur ett föräldraperspektiv2009Independent thesis Advanced level (professional degree), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

     

    The purpose of this study is to make the parents expectations on the schools liability, of when a child ends up in a situation where he/she gets bullied, visible. The study aims also at lifting the parents' thoughts and expectations of the work around the cooperation between the school and the home in this matter. The definition of bullying which underlies this study is: when some or someone repeatedly gets insulting treatment. Different types of bullying are presented to give a background to what bullying could mean. The study is a qualitative examination where seven parents, to children between the ages of 6-12, have been interviewed. The result shows that parents have high expectations on the schools in the matter of cooperation with the homes. It also showed that the parents expect the schools to mark that bullying is unacceptable. The parents also wish for measures and follow-ups in the event of a bullying situation. The conclusion is that commitment, availability and cooperation are important parts which the parents expect from the schools in the case of a bullying situation.

  • 10212.
    Yüksel, Simon
    et al.
    University of Skövde, School of Technology and Society.
    Sedin, Peter
    University of Skövde, School of Technology and Society.
    Extern ekonomisk kompetens: Familjeföretag och anlitandet av extern ekonomisk kompetens2012Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Research on family business is quite extensive. But there are still many questions that remain unanswered. An important issue relating to family business development is the desire to bring in external expertise in the finance area. It may involve services such as finance manager, controller or accountant. In this work the authors have attempted to answer the question of why the management of family businesses chooses to bring in external expertise in economics. The theory implies that the family business as long reluctant to bring in external expertise for the benefit of their own family members. The conclusions to be drawn after evaluating responses from eight family business CEOs and externally added staff in finance is that they are mostly very much welcoming the appointment of external staff in finance. Most of the view implies that without the addition of external staff, the companies would not develop as successfully as they have done. They see external staff within the finance area as strength for the new knowledge, experience and skills that businesses will benefit from. Many CEO: s advocates that you get in a person who can come up with other solutions to the problems than the conventional ones, but also a less emotional approach to family business affairs, which may be a distinct advantage. New ideas and knowledge will benefit the company. However, the personal dynamics of the external competence are of great importance to companies in the survey, it should fit into the entrepreneurial spirit and be easy to deal with, but still have privacy. Disadvantages as some have pointed out are for example, if the externally appointed expert may terminate their service or manipulate the records.

    Given all the laws and regulations that govern todays businesses requires a lot of expertise in economics, especially in the consolidated financial statements, taxation, financial statement and annual reports. This knowledge can in a few cases be met by family members, but in the vast majority of companies, you need to get the skills into the company from outside.

    We believe that our study has given us answers to the questions we had put up on the family company's approach to the use of external expertise in economics. Namely, those family businesses that want to develop win a lot of hiring external expertise in economics. Not just economically but also in many other areas.

    Keywords: Family firm, External financial competence, Corporate governance, Complexity of family firms, Succession planning. 

  • 10213.
    Zadencki, Michal
    University of Skövde, School of Humanities and Informatics.
    "Tystnad, Tagning": en undersökning om ljud och musikläggning av kortfilm2010Independent thesis Basic level (university diploma), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Målet med detta examensarbete är att få en inblick i hur de olika processerna i arbetet med ljud till film fungerar. Jag vill kunna utröna hur man bäst tar sig an de olika processerna samt vilka fallgropar som kan bli aktuella.

  • 10214.
    Zafran, Ulrika
    et al.
    University of Skövde, School of Technology and Society.
    Mohlin Z, Emmelie
    University of Skövde, School of Technology and Society.
    Tillbaka till samhället: En undersökning av unga vuxna deltagare i verksamheten Catch Up2011Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Fokuset i denna uppsats ligger på att undersöka hur vilken roll Catch Up spelar för de unga vuxnas återintegrering i samhället via studier och arbete. Studien vill vidare undersöka om större förmåga att integrera sig i samhället stärker deltagarens egen roll i samhället, ändrar dennes attityder mot sig själv och andra samt ökar kommunikationsförmågan. Genom denna studie hoppas vi kunna bidra till en ökad förståelse av de socialpsykologiska problem som de unga vuxna deltagarna i Catch Up upplever samt kunna förklara de problem mekanismer som försvårar unga vuxnas integrering i samhället. Verksamheten Catch Up ligger i Skövde kommun och är en del av socialtjänsten. Verksamhetens mål är myndighetssamverkan kring unga vuxna i åldrarna 18-29. För att delta i verksamheten ska individen vara beroende av försörjningsstöd samt ha ett hinder av någon form, t ex. psykisk ohälsa. Uppsatsen utgår från den symbolisk interaktionistiska traditionen med inslag av teorin om symboliskt kapital. Tillvägagångssättet har en kvalitativ grund med semistrukturerad intervju, där åtta deltagare på Catch Up intervjuades. Resultatet visade att uppmärksamheten individerna får från Catch Ups personal gör att de kan ändra sin attityd gentemot sig själv och samhället till mer positivt. Dessutom ökar och effektivera de sin kommunikationsförmåga samt skapar en större tillit till sin sociala kontext.

  • 10215.
    Zaher, Fadi
    University of Skövde, School of Technology and Society.
    Evaluating Asset-Pricing Models in International Financial Markets2006Doctoral thesis, monograph (Other scientific)
    Abstract [en]

    This thesis consists of three empirical studies on asset-prices in international financial markets. The purpose is three-fold. First, to evaluate whether good predictions of economic variables may be obtained by pooling information from a broad group of financial variables. Second, to formulate asset-pricing models from seven established stock markets. Third, to evaluate the asset-pricing models in the presence of short-sales.

    Chapter 2 applies a large data set, consisting of 167 monthly time series for the UK, both economic and financial, to simulate out-of-sample predictions of industrial production, inflation, three-month Treasury-Bills and other variables. Fifteen dynamic factor models that allow forecasting based on large panels of time series are considered. The performances of these factor models are then compared to the following competing models: a simple univariate autoregressive, a vector autoregressive, a leading indicator, and a non-expectational Phillips curve models. The results show that the dynamic factor models outperform the competing models in forecasting at 6-, 12-, and 24-month horizons. Two main findings are highlighted. First, the financial markets have a predictive power in terms of economic activity. Second, for some variables, the dynamic factor model appears to be more reliable than other competing models.

    In an attempt to analyze the equity premium puzzle and the risk-free rate puzzle, Chapter 3 compares different asset-pricing models within an international framework. To do so, it evaluates the performance of the following models: time separable-constant relative risk aversion, internal habit, external habit with externality, external habits which yield a constant risk-free rate, adaptive learning with constant gain, and state non-separability. The data are from seven industrialized countries, namely the United States, Canada, Japan, the United Kingdom, France, Denmark, and Sweden. Regarding empirical evidence, this thesis uses the Hansen-Jagannathan approaches to impose volatility restrictions on the asset-pricing models. The time-separable, adaptive learning and external habit models fail, and the evidence favors the internal habit persistence model. However, success is limited to some countries and to the equity premium puzzle rather than the risk-free rate puzzle. Finally, the state-non-separable specification consistently resolves the equity premium puzzle for all the countries.

    Chapter 4 analyzes the effect of market frictions on the equity premium puzzle. Indeed, in the standard asset-pricing model with time-separable preferences, the volatility of the intertemporal marginal rate of substitution is too low for plausible values of risk aversion to be consistent with consumption and asset return data. Following this, the Hansen-Jagannathan method is applied to evaluate the equity premium puzzle for the UK in two directions. First, the time-separable model, the internal and the external habit formation models and the state non-separable model are examined under the assumptions of both frictionless markets and market frictions. Second, a bootstrap experiment is conducted to show that these asset-pricing models violate the Hansen-Jagannathan bound in almost all the samples. Indeed, because of the changes in the sample means in consumption growth and asset returns, all the models appear to be weak under frictionless markets. By contrast, asset-pricing models with market frictions are much more successful in the bootstrap experiment.

  • 10216.
    Zaher, Fadi
    University of Skövde, School of Technology and Society.
    What is the Impact of Market Friction on Utility Based Asset Pricing Theory?2006In: European Economic Association (EEA): Proceeding from Vienna 24 – 28 august 2006, 2006Conference paper (Other academic)
  • 10217.
    Zamanian, Max
    University of Skövde.
    An evaluation of portofolio management strategies: A case of Swedish mutual fund market2004In: Economics and Management, 2004, p. 98-101Conference paper (Other academic)
  • 10218.
    Zamanian, Max
    University of Skövde, School of Humanities and Informatics.
    The Accuracy in Financial Statements and the Efficient Market Hypothesis2005In: International Conference Proceedings of Economics and Management 2005, 2005, p. 322-325Conference paper (Other academic)
  • 10219.
    Zander, Sebastian
    University of Skövde, School of Informatics.
    Händelsehantering i komponentbaserade spelmotorer: Utvärdering av två tekniker2015Independent thesis Basic level (degree of Bachelor), 20 credits / 30 HE creditsStudent thesis
    Abstract [sv]

    Spelmotorer är en viktig del av utveckling av spel. Spel är i grunden händelsebaserade och tillåter spelentiteter att reagera på omvärlden. Syftet med det här arbetet är att utvärdera två metoder för händelsehantering i en komponentbaserad spelmotor och hur dessa påverkar tidsprestandan: en baserad på polymorfism med virtuella funktioner och en baserad på reflektion. Systemet för händelsehantering implementeras i en simpel simulering av en spelmotor och uppdateringstiden för vardera metod mäts utifrån olika variabler som påverkar dess prestanda. Systemen utvärderas i olika typer av spelmiljöer med olika mängd entiteter, olika mängd händelser per uppdatering etc. Händelsehantering baserat på reflektion visar på bättre prestanda i de flesta fall, vilket troligen beror på att funktioner för händelser endast behöver anropas på komponenter som använder händelsen.

  • 10220.
    Zandén, Camilla
    University of Skövde, Department of Computer Science.
    Just-In-Time: mänskliga och organisatoriska faktorer1997Independent thesis Basic level (degree of Bachelor)Student thesis
    Abstract [sv]

    Produktionsstyrningen på företagen runt om i världen är i ständig förändring. Ett begrepp som ofta används för japanska logistiska idéer är Just-In-Time (JIT). Vad som egentligen innefattas i JIT beror på vilken författare man läser. För det mesta belyses de produktionstekniska delarna av JIT.

    En del av Just-In-Time som mer sällan tas upp i litteraturen är faktorer som ibland anses som grundläggande för att JIT ska fungera framgångsrikt på företagen. Många av dessa faktorer är något mjukare aspekter av Just-In-Time. Det är om dessa mjukare faktorer mitt arbete handlar.

    Jag ska i mitt examensarbete undersöka om ett antal faktorer som tillämpas på japanska företag även tillämpas på företag i Sverige. De olika faktorer mitt arbete kretsar kring är i korthet följande:

    - Jobbrotation

    - Gemensamt beslutsfattande

    - Självstyrande grupper

    - Teamwork och grupptillhörighet

    - Möjlighet till långsiktig personalpolitik

    - Omfattande utbildning

    - Gemensamt språk inom företaget

    - Aktiv förslagsverksamhet

    - Synbarhet för alla

    - Lönesystem

    Undersökningen går ut på att få reda på om dessa faktorer är något som tillämpas på företag i Sverige. Jag vill även undersöka i vilken utsträckning de olika faktorerna tillämpas.

    Jag har valt att använda mig av en enkätundersökning för att få reda på om de olika faktorerna tillämpas i Sverige. De företag som var aktuella för att passa in på min problemställning var tillverkande företag i Skaraborg med mellan 100 och 500 anställda. Jag ringde och talade med den produktionsansvarige på företagen och berättade om mitt examensarbete innan jag skickade ut enkäterna.

    Utifrån enkätsvaren kunde jag dra slutsatserna att samtliga faktorer tillämpas på företag i Sverige. Jag kunde även dra slutsatsen att det inte är ovanligt att faktorerna tillämpas. Det fanns ingen faktor som verkade helt främmande för företagen. Jag ansåg mig även kunna säga vilken faktor som tillämpas mest och vilken som tillämpas minst. Den faktor som verkar vara vanligast är ‘Möjlighet till långsiktig personalpolitik’ och den faktor som verkar vara ovanligast är ‘Gemensamt beslutsfattande’.

    Förslag till fortsatt forskning anser jag kunna vara att undersöka ytterligare mjuka faktorer, eventuellt med inriktning på attityder, trender och vilken kunskap som finns på svenska företag om dessa eller andra faktorer.

  • 10221.
    Zaqout, M.
    et al.
    Univ Ghent, Dept Publ Hlth, Fac Med & Hlth Sci, Ghent, Belgium.
    Michels, N.
    Univ Ghent, Dept Publ Hlth, Fac Med & Hlth Sci, Ghent, Belgium.
    Bammann, K.
    Univ Bremen, Inst Publ Hlth & Nursing Res, Fac Human & Hlth Sci, Bremen, Germany.;Leibniz Inst Prevent Res & Epidemiol BIPS, Bremen, Germany.
    Ahrens, W.
    Leibniz Inst Prevent Res & Epidemiol BIPS, Bremen, Germany.
    Sprengeler, O.
    Leibniz Inst Prevent Res & Epidemiol BIPS, Bremen, Germany.
    Molnar, D.
    Univ Pecs, Fac Med, Dept Pediat, Pecs, Hungary.
    Hadjigeorgiou, C.
    Res & Educ Inst Child Hlth, Strovolos, Cyprus.
    Eiben, Gabriele
    Univ Gothenburg, Sahlgrenska Acad, Dept Publ Hlth & Community Med, Publ Hlth Epidemiol Unit EPI, Gothenburg, Sweden.
    Konstabel, K.
    Natl Inst Hlth Dev, Dept Chron Dis, Ctr Behav & Hlth Sci, Tallinn, Estonia.
    Russo, P.
    CNR, Inst Food Sci, Unit Epidemiol & Populat Genet, Avellino, Italy.
    Jimenez-Pavon, D.
    Univ Zaragoza, GENUD Growth Exercise Nutr & Dev Res Grp, Zaragoza, Spain.
    Moreno, L. A.
    Univ Zaragoza, GENUD Growth Exercise Nutr & Dev Res Grp, Zaragoza, Spain.
    De Henauw, S.
    Univ Ghent, Dept Publ Hlth, Fac Med & Hlth Sci, Ghent, Belgium.
    Influence of physical fitness on cardio-metabolic risk factors in European children. The IDEFICS study2016In: International Journal of Obesity, ISSN 0307-0565, E-ISSN 1476-5497, Vol. 40, no 7, p. 1119-1125Article in journal (Refereed)
    Abstract [en]

    OBJECTIVE: The aim of the study was to assess the associations of individual and combined physical fitness components with single and clustering of cardio-metabolic risk factors in children. SUBJECTS/METHODS: This 2-year longitudinal study included a total of 1635 European children aged 6-11 years. The test battery included cardio-respiratory fitness (20-m shuttle run test), upper-limb strength (handgrip test), lower-limb strength (standing long jump test), balance (flamingo test), flexibility (back-saver sit-and-reach) and speed (40-m sprint test). Metabolic risk was assessed through z-score standardization using four components: waist circumference, blood pressure (systolic and diastolic), blood lipids (triglycerides and high-density lipoprotein) and insulin resistance (homeostasis model assessment). Mixed model regression analyses were adjusted for sex, age, parental education, sugar and fat intake, and body mass index. RESULTS: Physical fitness was inversely associated with clustered metabolic risk (P<0.001). All coefficients showed a higher clustered metabolic risk with lower physical fitness, except for upper-limb strength (beta = 0.057; P = 0.002) where the opposite association was found. Cardio-respiratory fitness (beta = -0.124; P<0.001) and lower-limb strength (beta = -0.076; P = 0.002) were the most important longitudinal determinants. The effects of cardio-respiratory fitness were even independent of the amount of vigorous-to-moderate activity (beta = -0.059; P = 0.029). Among all the metabolic risk components, blood pressure seemed not well predicted by physical fitness, while waist circumference, blood lipids and insulin resistance all seemed significantly predicted by physical fitness. CONCLUSION: Poor physical fitness in children is associated with the development of cardio-metabolic risk factors. Based on our results, this risk might be modified by improving mainly cardio-respiratory fitness and lower-limb muscular strength.

  • 10222.
    Zaqout, Mahmoud
    et al.
    Department of Public Health, Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan 185, 4K3, Ghent, Belgium.
    Michels, Nathalie
    Department of Public Health, Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan 185, 4K3, Ghent, Belgium.
    Ahrens, Wolfgang
    Leibniz Institute for Prevention Research and Epidemiology BIPS, Bremen, Germany.
    Börnhorst, Claudia
    Leibniz Institute for Prevention Research and Epidemiology BIPS, Bremen, Germany.
    Molnár, Dénes
    Department of Pediatrics, Medical Faculty, University of Pécs, Pécs, Hungary.
    Moreno, Luis A.
    GENUD (Growth, Exercise, Nutrition and Development) Research Group, University of Zaragoza, Zaragoza, Spain.
    Eiben, Gabriele
    Department of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
    Siani, Alfonso
    Epidemiology and Population Genetics, Institute of Food Sciences, National Research Council, Avellino, Italy.
    Papoutsou, Stalo
    Research and Education Institute of Child Health, Strovolos, Cyprus.
    Veidebaum, Toomas
    Department of Chronic Diseases, National Institute for Health Development, Tallinn, Estonia.
    De Henauw, Stefaan
    Department of Public Health, Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan 185, 4K3, Ghent, Belgium.
    Associations between exclusive breastfeeding and physical fitness during childhood2018In: European Journal of Nutrition, ISSN 1436-6207, E-ISSN 1436-6215, Vol. 57, no 2, p. 545-555Article in journal (Refereed)
    Abstract [en]

    PURPOSE: Exposure to breastfeeding improves the survival, health, and development of children; therefore, breast milk is recommended as the exclusive nutrient source for feeding term infants during the first 6 months. This cross-sectional study aimed to determine the possible association between exposure to exclusive breastfeeding and physical fitness performance in children and, if so, whether this association is influenced by the breastfeeding duration.

    METHODS: A total of 2853 (52.3 % girls) European children from the IDEFICS study aged 6-11 years with complete data on physical fitness (cardiorespiratory fitness, muscular strength, flexibility, balance, speed) and exclusive breastfeeding duration (never, 1-3, 4-6, 7-12 months) were included in the present study. Multivariate and mixed linear regression models were estimated and adjusted for sex, age, birth weight, diet, physical activity, body mass index, and parental factors (age, body mass index, educational attainment).

    RESULTS: We found a positive association between exclusive breastfeeding and lower-body explosive strength (β = 0.034) as well as flexibility (β = 0.028). We also found a positive association between breastfeeding and balance in boys (β = 0.039), while this association was negative in girls (β = -0.029). To improve lower-body explosive strength, 1-3 months of exclusive breastfeeding were enough; a longer duration did not lead to increasing benefit. In contrast, 4-6 months of breastfeeding were necessary to have any benefit on flexibility or balance, although this became nonsignificant after adjustment for body mass index and physical activity.

    CONCLUSIONS: Exclusive breastfeeding seems a natural way of slightly improving some physical fitness components (mainly lower-body muscle strength) and thus future health.

  • 10223.
    Zare, Zahra
    et al.
    Department of Statistics and Epidemiology, Faculty of Health, Tabriz University of Medical Sciences, Iran.
    Sadeghi-Bazargani, Homayoun
    Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Iran.
    Ranjbar, Fatemeh
    Research Center of Psychiatry and Behavioral sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
    Stark Ekman, Diana
    University of Skövde, School of Health and Education. University of Skövde, Health and Education.
    Farahbakhsh, Mostafa
    Health Services Management Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
    Maghsoudi, Hemmat
    Department of Surgery, Sina Burn Center, Tabriz University of Medical Sciences, Iran.
    Ekman, Robert
    Department of Architecture and Civil Engineering, Chalmers University of Technology, Gothenburg, Sweden.
    Nasiri, Farideh
    Sociologist at Tabriz University of Medical Sciences, Iran.
    Psychometric Properties of a New Instrument for Assessing Irrational Thoughts in Burn Victims (Scale of Irrational Thoughts After Burn Injuries)2017In: Journal of Burn Care & Research, ISSN 1559-047X, E-ISSN 1559-0488, Vol. 38, no 5, p. e834-e841Article in journal (Refereed)
    Abstract [en]

    The objective of this study was to develop and evaluate a scale for assessing irrational thoughts among burned patients. The present study was mixed (qualitative-methodologic) which was performed in several stages such as investigating similar or related scales, interviewing with patients and psychologists. Content validity was calculated by modified KAPPA basis on relevance and clarity. The reliability of the scale was measured using internal consistency and the test-retest method. To determine the construct validity, exploratory factor analysis approach using maximum likelihood extraction with varimax rotation was conducted. A total of 329 burned patients were recruited from Tehran, Tabriz, and Kermanshah provinces of Iran. Modified kappa scores were 0.80 and 0.91 for relevance and clarity of the items included in scale. The Cronbach alpha for overall scale, subscale 1, and subscale 2 were 0.89, 0.88, and 0.8, respectively. Test-retest reliability was also acceptable (intraclass correlation coefficient = 0.80). The best solution from the maximum likelihood analysis of the 39 items of the scale revealed two factors corresponding to the two subscales with 14 items that subscale 1 (self-acceptance) consisted of 10 statements accounting for 60% of the variance (eigenvalue = 5.04) and subscale 2 (distastefulness and pity) consisted of four statements accounting for 40% of the variance (eigenvalue = 1.53). The scale reflects acceptable levels of validity and reliability in assessing the irrational thoughts among Iranian patients. Moreover, the testing populations of both patients with burned faces and patients with other burned body parts indicates that the scale may also be applicable for patients' burn disfigurements on any part of their bodies.

  • 10224.
    Zare, Zahra
    et al.
    Tabriz University of Medical Sciences, Tabriz, Iran.
    Sadeghi-Bazargani, Homayoun
    Tabriz University of Medical Sciences, Tabriz, Iran.
    Stark Ekman, Diana
    University of Skövde, School of Health and Education. University of Skövde, Health and Education.
    Ranjbar, Fatemeh
    Tabriz University of Medical Sciences, Tabriz, Iran.
    Ekman, Robert
    Chalmers University of Technology, Göteborg, Sweden.
    Farahbakhsh, Mostafa
    Tabriz University of Medical Sciences, Tabriz, Iran.
    Maghsoudi, Hemmat
    Tabriz University of Medical Sciences, Tabriz, Iran.
    Cognitive Distortions as Trauma-Specific Irrational Beliefs Among Burn Patients2019In: Journal of Burn Care & Research, ISSN 1559-047X, E-ISSN 1559-0488, Vol. 40, no 3, p. 361-367Article in journal (Refereed)
    Abstract [en]

    Burn injuries are most certainly stressful events, particularly when permanent disfigurement is a result. This situation can lead to the onset of irrational beliefs which can in turn lead to long-term psychological problems such as depression, anxiety, shame, guilt, posttraumatic stress, etc. The objective of this study is to explore the irrational beliefs among burn patients and its correlates in an Iranian sample. This cross-sectional study included 329 patients who had experienced disfigurement, as result of burn injuries. In order to assess irrational beliefs, a Scale for Irrational Thoughts after Burning was used. To identify correlated variables with irrational beliefs, both bivariate and multivariate analysis methods were conducted. In multivariate linear regression, forward strategy was used for building the model. The results of bivariate analysis showed that the location of the burn on bodies (body parts generally exposed in social environment or parts culturally perceived as sensitive areas of body), marital status, urbanities, age group, geographical areas, etiology of burning, and intent of injury had significant relationships with irrational beliefs (P < .05). Using forward linear regression, gender, marital status, geographical areas, etiology of burning, body burn by location (body parts generally exposed in social environment or parts culturally perceived as sensitive areas of body), and intent of injury had significant correlation with irrational beliefs. The models predicted 15.5% (P < .001) of irrational beliefs. Considering to irrational beliefs and development of facilities for screening is necessary. Moreover, consultation with mental health experts after burn injuries is highly recommended. 

  • 10225.
    Zaxmy, Hanna
    University of Skövde, Department of Computer Science.
    The 2G method applied in a post-usage evaluation application2003Independent thesis Advanced level (degree of Master (One Year))Student thesis
    Abstract [en]

    There exist several methods, which can be used for evaluation of commercially available CASE-tools. Each method has its own focus and is based on specific underlying assumptions. There have been attempts to standardise evaluation of CASE-tools; however available methods differs much from each other.

    One such method, named the 2G method has been proposed, which for each application, will establish a specific evaluation framework. This framework is tailored to the organisation at a specific point in time (since an organisation will change over time). The method consists of two phases which are iterated a sufficient number of times before a stable evaluation framework will be the result. The 2G method has been successfully applied on several applications in different organisations, though only for evaluation of CASE-tools before adoption. In this dissertation we report on an application of the 2G method, which aims to evaluate a CASE-tool from a company context which has already adopted a CASE-tool. As part of this method application the 2G method has also been transferred to the organisation.

    An additional issue this dissertation addresses is what kind of support a general Qualitative Research Tool will offer a method user when using the tool in a 2G method application. Likewise the goal includes to establish is what is poorly or unsupported in such tool in a 2G application.

    This dissertation will show that the 2G method is applicable also in a scenario where a CASE-tool has already been adopted, and therefore demonstrate that the method also is useful in evaluation studies performed after a CASE-tool has been adopted in an organisation. From the experiences of the application points will be made concerning what kind of support one would like to have in a qualitative research tool to simplify the work during the 2G applications.

  • 10226.
    Zaytoun, Maria
    University of Skövde, School of Health and Education. mariazaytoun@hotmail.com.
    Sjuksköterskors erfarenheter av att vårda och bemöta äldre med demenssjukdom: En litteraturbaserad studie2018Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: Dementia is a common disease and is among the leading causes of disability amongst elderly people. Dementia disease can lead to personality changes, memory disorders, confusion and communication difficulties, amongst other things. These symptoms demand nurses to adapt their way of nursing and treating to offer the best possible care. Aim: The aim with a literature-based study is to describe nurses’ experiences with nursing and treating elderly with dementia disease. Method: In the following study a total of 10 articles of qualitative nature have been reviewed and analyzed in a structured manner. Result: The following four themes have been identified regarding the studied articles; The caring creates a variety of emotions, the importance of having prerequisites, knowledge about the individual behind the disease and the importance of being able to communicate and interact. Conclusion and clinical implications: Good treatment is a prerequisite for good care. To treat elderly with dementia the right preconditions like, time, a person-centered approach, knowledge about the disease and communication skills are necessary. The result can contribute to an increased understanding of nurses by describing other nurses' actual experiences of how nursing and treatment of elderly with dementia disease can be seen in practice.   

  • 10227.
    Zdilar, Mihael
    University of Skövde, Department of Computer Science.
    Analys av en metod för att extrahera generella regler från multipla nät1998Independent thesis Basic level (degree of Bachelor)Student thesis
    Abstract [sv]

    Rapporten som följer är en analys av en metod som genererar regler från neurala nätverk. Metoden heter VI-Analysis (Validity Interval Analysis) och är framtagen av Sebastian B. Thrun [Thrun]. VI-Analysis arbetar på det sättet att det neurala nätverket ses som en svart låda där endast de inputvärden och outputvärden som finns i nätverket används som underlag när regler ska genereras. Dessa inputvärden och outputvärden kommer sedan att få tillåtna intervall av VI-Analysis. De regler som tas fram av VI-Analysis är av typen if-then, dvs if (inputvärdet är inom ett tillåtet intervall) then (outputvärdet kommer att hamna inom ett tillåtet intervall). Om däremot det neurala nätverket har två eller fler lager kommer VI-Analysis att med största sannolikhet beräkna ett för stort intervall för outputvärdet. Detta kommer att granskas och det kommer att visas att VI-Analysis inte tar med alla de beroenden som finns mellan nätverkets vikter i sin beräkning. Om ett nätverk består av två eller fler lager och vikterna i nätverket är av olika tecken (+/-) kommer VI-Analysis att misslyckas att generera det exakta intervallet för ut-noden i nätverket. En metod för att minska detta fel kommer därför att presenteras.

  • 10228.
    Zdybal, Johan
    University of Skövde, School of Informatics.
    Grafiska stilars påverkan på spelupplevelsen: Kan den grafiska stilen påverka en spelares uppfattning av spelupplevelsen?2014Independent thesis Basic level (university diploma), 20 credits / 30 HE creditsStudent thesis
    Abstract [sv]

    Detta arbete gick ut på att undersöka ifall två spelmekaniskt identiska spelprototyper med två olika grafiska stilar kunde påverka en spelares uppfattning av spelupplevelsen. Syftet var inte att undersöka hur det påverkar utan om det påverkar. Arbetet utgick ifrån att undersöka grafiska stilar, skapa två spelprototyper samt undersöka och bryta ner spelupplevelsen med hjälp av Swinks bok om Game Feel. Åtta respondenter deltog i speltest och intervjuer vilket ledde till data som kunde konstatera att en grafisk presentation, en grafisk stil, påverkar en spelares upplevelser av ett spel. Datan kan inte påvisa hur, däremot att det sker något, trots mekaniskt identiska spel. För framtida forskning vore det intressant att använda ett större och mer komplext spel för att ge ett längre och mer naturligt speltest för respondenterna samt för att likna de spel som finns tillgängliga i handeln idag.

  • 10229.
    Zeijlon, Jessika
    et al.
    University of Skövde, School of Life Sciences.
    Lidestam, Magdalena
    University of Skövde, School of Life Sciences.
    Vad förebygger depression bland äldre: en litteraturstudie2012Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Late-life depression is a major public health problem which causes emotional suffering among individuals and their relatives, and also leads to increased health care costs. In Sweden the prevalence of late-life depression is approximately 12-15 % among those aged 65 and older. The aim of this literature review was to compile and examine previous research considering late-life depression-preventive factors. Literature searches were made in the databases LibHub, PubMed and Cinahl using the keywords: prevention, depression, depressive symptoms, elderly, old and old people. Twelve scientific articles were selected and analyzed. Five main themes were identified. Theme activity showed conflicting results, dietary supplements were effective in one of two studies and social support was an important factor in preventing depression and counteracts the negative effects of stressful life events and economic stress. Cognitive strategies such as “positive restructuring” and CBT treatment were found to have an effect on depression symptoms. An intervention program including training of nursery care staff had significant effect, especially in nursing homes with a high prevalence of depression. Conclusion: Further literature studies and further deepening of the different themes are needed to draw accurate conclusions. There is a need for more research in this area, larger studies and longer follow-up is needed.

  • 10230.
    Zeijlon, Robin
    et al.
    University of Skövde, School of Informatics.
    Waller, Vanja
    University of Skövde, School of Informatics.
    Hur virtuella verklighetsglasögon gör skillnad: En jämförelsestudie av ett multiplayerskräckspel med och utan virtuella verklighetsglasögon2019Independent thesis Basic level (degree of Bachelor), 20 credits / 30 HE creditsStudent thesis
    Abstract [sv]

    I detta arbete undersöks på vilket sätt virtuella verklighetsglasögon förändrar en spelupplevelse. Primärt ligger fokus på vad fysisk immersion och sensorisk feedback kan tillföra till spelupplevelsen. Detta innefattar autenticitet och inlevelse.För att undersöka detta används en utav karaktärerna i multiplayerskräckspelet Strobophagia som är omgjord för att fungera med virtuella verklighetsglasögon. I varje test fick en försöksdeltagare spela den omgjorda karaktären och dess originalversion medan en försöksdeltagare fick agera som motståndare och spela den icke omgjorda karaktären.Resultatet visar tydligt på att versionen i virtuell verklighet föredras av försöksdeltagare då den har ökad immersion och användbarhet. Fortsättningsvis anses den även vara mindre av ett spel och mer som en upplevelse. I framtiden behöver detta testas på fler spel och genrer för att säkerhetsställa att resultatet inte är unikt för Strobophagia.

  • 10231.
    Zelander Bävholm, Charlotta
    University of Skövde, School of Humanities and Informatics.
    Form och Karaktärsdesign: Formens påverkan på hur människor uppfattar datorspelskaraktärer2013Independent thesis Basic level (degree of Bachelor), 20 credits / 30 HE creditsStudent thesis
    Abstract [sv]

    Denna undersökning syftade till att undersöka om människor uppfattade karaktärers personlighet olika beroende på vilken geometrisk form som vävts in i deras design. För att ge en bakgrund till undersökningen går arbetet igenom tidigare undersökningar gällande geometriska former och känslor, ikonografisk analys av bilder på karaktärer, stereotypiska karaktärer och karaktärsdesign.

    Som material för undersökningen skapades sex stycken konceptbilder på karaktärer, en kvinnlig och en manlig för var av de geometriska former som undersöktes: Cirkel, rektangel och triangel. Undersökningen utfördes med hjälp av en enkät där högstadieelever fick kryssa i de personlighetsdrag de förknippade med de olika karaktärerna, samt motivera sina val.

    Resultatet visade att geometriska former påverkade hur respondenterna uppfattade karaktärernas personlighet, men också att många andra attribut spelade en roll, som till exempel ansiktsdrag, kroppshållning och kläder. Slutsatsen skulle kunna bevisas bättre om fler, liknande arbeten gjordes, som fokuserade på flera åldersgrupper eller ställde fler djupgående frågor.

  • 10232.
    Zetterberg, Stefan
    et al.
    University of Skövde, School of Technology and Society. University of Skövde, School of Technology and Society.
    Into, Camilla
    University of Skövde, School of Technology and Society.
    Transitlager som en strategi i ett globalt distributionssystem2009Independent thesis Basic level (degree of Bachelor), 20 credits / 30 HE creditsStudent thesis
    Abstract [sv]

    Nuförtiden är det stora flertalet försörjningskedjor internationella till sin karaktär och trenden går alltmer mot fokuserade fabriker. Det innebär att ett fåtal fabriker som var och en fokuserar på ett fåtal produkter tar hand om produktionen för hela världsmarknaden. Då tillverkningen sker på få utvalda platser och marknader världen över ska försörjas ifrån dessa krävs ett globalt distributionssystem som ska klara av att hantera den ökade konkurrensen, kundernas krav på kortare ledtider och den ökade differentieringen av produkter.

    Det finns olika strategier för att hantera ett globalt distributionssystem. Syftet med denna uppsats är att utreda om en transitlagerstrategi kan vara ett konkurrenskraftigt komplement eller alternativ till de mer vanligt förekommande distributionsstrategierna. Studien har gjorts genom att skapa ett teoretiskt ramverk vilket beskriver hur det globala distributionssysteme kan hanteras. Med förutsättningen att företagen idag har ett globalt distributionssystem måste de kunna distribuera sina varor över hela världen och teorin behandlar tre distributionsstrategier för att hantera detta och det är centraliserad distributionsstrategi, decentraliserad distributionsstrategi och transitlagerstrategi. De olika distributionsstrategiernas egenskaper samt för- och nackdelar beskrivs för att avgöra i vilka affärsmiljöer respektive strategi lämpar sig.

    Det teoretiska ramverket behandlar hur företag kan välja mellan och kombinera de olika distributionsstrategierna utifrån deras förutsättningar att produkterna ska nå många marknader från ett fåtal fabriker. För att underlätta valet av distributionsstrategi har en matris konstruerats i ramverket. Matrisen bygger på ett antal utvalda variabler vilka är viktiga att ta hänsyn till. Avslutningsvis när en strategi eller en kombination av strategier är vald ska teorin behandla hur företagen praktiskt kan arbeta med de olika strategierna.

    Empirin kommer att redogöra för två fallstudier där de olika företagen är Etylenaminer och Eka Chemicals. Det kommer att beskrivas hur deras distributionssystem ser ut idag, vilka distributionsstrategier som de använder samt hur de arbetar praktiskt med dem.

    I analysen har det teoretiska ramverket ställts emot den insamlade empirin för att utreda om transitlagerstrategin kan vara ett konkurrenskraftigt komplement till den centrala distributionsstrategin och den decentraliserade distributionsstrategin. Den slutsats som forskningen leder fram till är att det finns mer än ett sätt att strukturera distributionssystemet på och genom det bli framgångsrik på en global marknad. Oavsett vilket distributionssystem ett företag har byggt upp kan transitlagerstrategin utgöra ett bra komplement eller alternativ till den centraliserade distributionsstrategin och den decentraliserade distributionsstrategin för att vinna konkurrensfördelar på marknaderna. Transitlagerstrategin kan bland annat ge upphov till kortare ledtider än vad som kan uppnås med den centraliserade distributionsstrategin och mindre kapitalbindning än vad tillämpningen av den decentraliserade distributionsstrategin ger genom att produkten inte behöver lagras lokalt för att erbjuda kunden korta ledtider. Forskningen visar vidare på att det tar mycket lång tid att utveckla en renodlad transitlagerstrategi men att företagen redan i de tidiga utvecklingsfaserna av strategin kan tillgodogöra sig stora konkurrensfördelar.

  • 10233.
    Zetterlund, Marie
    University of Skövde, Department of Computer Science.
    Infology: a study to identify possible elements of infology in some system development methodologies1999Independent thesis Advanced level (degree of Master (One Year))Student thesis
    Abstract [en]

    The purpose of this work is to identify possible elements of infology in some systems development methodologies. To reach the aim two objectives were identified: to gain an understanding of the concept of infology and secondly to study different kinds of methodologies and analyse them to find out possible elements of infology. In order to reach the aim of this work a literature study was performed. Four methodologies were chosen for the analysis and the selection represented a wide range of different methodologies. They were: Soft Systems Methodology (SSM), Effective Technical and Human Implementation of Computer based Systems (ETHICS), Structured Systems Analysis and Design Method (SSADM) and Yourdon Systems Method (YSM). The infological approach has been characterised and the fundamental characteristic of infology is the distinction between data and information. A consequence from this distinction is that the users of the intended information system should participate in the developing process in order to understand the complex and dynamic relations in an organisation and information system. The results of this work have shown that the soft methodologies (SSM and ETHICS) have a high degree of infology and the more hard methodologies (SSADM and YSM) have a low degree of infology.

  • 10234.
    Zetterlund, Marie
    University of Skövde, Department of Computer Science.
    Intranät: en belysning av eventuella problem och åtgärder1998Independent thesis Basic level (degree of Bachelor)Student thesis
    Abstract [sv]

    I detta arbete har jag valt att intervjua representanter från 5 större företag som är ledande inom sitt verksamhetsområde. Syftet med denna rapport är att belysa intranätansvarigas syn på de problem och risker som kan uppkomma med intranät som elektronisk informationsmedium. De risker och problem som jag har tittat på är om det finns en risk för en användare att missa relevant information, få tillgång till för mycket information samt utsättas för för mycket information i ett intranät. Information har samlats in via intervjuer och litteraturstudier.

    Undersökningens slutsatser handlar i stort om de åtgärder som ett företag kan vidta för att förhindra att eventuella risker och problem skall uppkomma. Den viktigaste åtgärden är utbildning av den vanliga användaren. Rapporten avslutas med en diskussion kring ämnet samt några eget komponerade riktlinjer för införande av ett intranät i en verksamhet.

  • 10235.
    Zetterman, Karin
    University of Skövde, Department of Computer Science.
    Användarprofiler: kan de bidra till kvalitet i beslutsfattande?2002Independent thesis Basic level (degree of Bachelor)Student thesis
    Abstract [sv]

    Antalet intranät växer ständigt, samtidigt som allt fler människor känner att de inte kan ta till sig all den information som de erhåller. Intranäten innehåller en mängd användbar information som alla anställda kan ta del av. För att kunna använda intranätet effektivt krävs det att användarna sorterar bland all den information som finns på intranätet. Med hjälp av användarprofiler kan detta ske på ett enkelt sätt. Syftet med detta arbete var att behandla frågan om användarprofiler kan bidra till att bättre beslut tas genom att information overload reduceras. För att besvara arbetets frågeställning har telefonintervjuer med sju respondenter genomförts. Litteraturen som studerats inom detta arbete visar på att information overload kan leda till en mängd konsekvenser så väl för de anställda som företaget som helhet. Resultatet av telefonintervjuerna visar att användarprofiler används ute på företag samt att flera av respondenterna anser att dessa kan bidra till kvalitet i beslutfattandet genom reducering av information overload.

  • 10236.
    Zetterström, Viktor
    University of Skövde, School of Informatics.
    Väderlek: En studie i hur väder och klimatpåverkan på karaktärer i spel uppfattas av spelare2015Independent thesis Basic level (degree of Bachelor), 20 credits / 30 HE creditsStudent thesis
    Abstract [sv]

    Väder och klimat finns alltid i verkliga livet och ofta i spel. Men i spelen är det inte alltid vädret fungerar som det gör i verkligheten. Man kan säga att det finns tre kategorier av väder/klimatpåverkan på karaktärer i spel. En där vädret/klimatet inte påverkar karaktären, en där gameplay påverkas av det och en där karaktären också påverkas. Vilken av dessa nivåer föredrar de som spelar? Genom att skapa tre nästan identiska animationer med karaktären Super Mario, med dessa nivåer som skillnaderna, testas detta i denna studie. Efter att undersökningen var utförd visade det sig att den nivå som flest föredrog var den sista, där karaktären och gameplay påverkades. Det skulle gå att utveckla denna undersökning och användafler spel med olika genrer för att se om uppfattningen om väder/klimatpåverkan skiljer sig beroende på genre. Studiens resultat visar indikationer på detta.

  • 10237.
    Zgog, Zana
    et al.
    University of Skövde, School of Technology and Society.
    Wedberg, Åse
    University of Skövde, School of Technology and Society.
    Från fabriksförsäljning till fenomen?: Konkurrensmedels betydelse för en outlet2010Independent thesis Basic level (university diploma), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Denna uppsats handlar om konkurrensmedel och hur en outlet arbetar med dessa för att påverka konsumenter i deras val. Bakgrund till uppsatsen är den starka konkurrensen som idag finns inom kläd- och varumärkesbranschen. I takt med att allt fler butiker öppnar sina dörrar intensifieras kampen om konsumenterna. Därför vill vi studera hur en Factory Outlet, som ofta saknar de fördelar, som till exempel en centralt belägen butik har, får konsumenter att välja just dem. Problemställningen som skall belysas är vilka konkurrensmedel en outlet har att jobba med och vilka de faktiskt använder för att skapa en alldeles unik mix som medför att konsumenterna väljer just dem. Vi har därmed utformat en problemformulering som lyder: Vilket konkurrensmedel är det som främst påverkar konsumenten att åka till en outlet, och hur jobbar och använder en outlet olika konkurrensmedel? Syftet med vår uppsats är att utifrån ett företagsekonomiskt perspektiv beskriva hanteringen av olika konkurrensmedels betydelse för en outlet och dess kunder. Vi kommer att fördjupa oss i undersökningen av vilka konkurrensmedel som används och hur de används, samt varför konsumenterna väljer att besöka en outlet. Vi kommer att använda oss av teorier så som konkurrensmedelsmixen, sexhörningen och konsumenters butiksval. Vår undersökning är uppdelad i två delar och utgår ifrån både en kvalitativ- och kvantitativ ansats. Vi ser en klar fördel att använda sig av båda två, då detta medförde att vi begränsade några utav nackdelarna hos varje metod. Undersökningen genomfördes på en av nordens största outlet för varumärken, vid namn Vingåkers Factory Outlet. Den första delen av undersökningen innefattar en öppen individuell intervju med den valda outletens marknadsansvarig och den andra delen innehåller 60 individuella konsumentintervjuer. De centrala slutsatserna för uppsatsen är att Vingåkers Factory Outlets sortiment och varumärkesutbud är det konkurrensmedel, som har störst påverkan på konsumenternas val att åka till outleten. Det är även detta konkurrensmedel som vi kommit fram till att outleten satsar och arbetar mest med. Därför kan vi även konstatera att Vingåkers Factory Outlet prioriterar helt rätt i sitt arbete med de olika konkurrensmedlen.

  • 10238.
    Zhang, Dan
    et al.
    University of Ontario Institute of Technology.
    Wang, Lihui
    University of Skövde, School of Technology and Society. University of Skövde, The Virtual Systems Research Centre.
    Gao, Zhen
    University of Ontario Institute of Technology.
    An integrated approach for remote manipulation of a high-performance reconfigurable parallel kinematic machine2010In: Journal of manufacturing systems, ISSN 0278-6125, E-ISSN 1878-6642, Vol. 29, no 4, p. 164-172Article in journal (Refereed)
    Abstract [en]

    Flexible and effective manipulation is important and meaningful for the further development and applications of parallel manipulators in the industrial fields, especially for high performance manufacturing. Web-based manufacturing has emerged as an alternative manufacturing technology in a distributed environment. In this paper, an integrated approach is proposed for remote manipulation of the reconfigurable parallel kinematic machine (RPKM) based on sensor-driven Wise-ShopFloor framework. The concept of Wise-ShopFloor integrates the modules of detailed architecture design, module interactions, sensor data utilization and model predictive control. In order to demonstrate the efficiency of this novel methodology, an example of a five degrees-of-freedom (DOF) RPKM is developed for surface finishing. The reconfigurability, the necessary kinematic analysis, and the performance mapping of the 5-DOF RPKM are conducted so as to implement the proposed approach.

  • 10239.
    Zhang, Dan
    et al.
    School of Mechanical and Power Engineering, Nanjing University of Technology, China / Faculty of Engineering and Applied Science, University of Ontario Institute of Technology, Oshawa, Canada.
    Wang, Lihui
    University of Skövde, The Virtual Systems Research Centre. University of Skövde, School of Technology and Society.
    Gao, Zhen
    Faculty of Engineering and Applied Science, University of Ontario Institute of Technology, Oshawa, Canada.
    Su, Xiaoping
    School of Mechanical and Power Engineering, Nanjing University of Technology, Nanjing, China .
    On performance enhancement of parallel kinematic machine2013In: Journal of Intelligent Manufacturing, ISSN 0956-5515, E-ISSN 1572-8145, Vol. 24, no 2, p. 267-276Article in journal (Refereed)
    Abstract [en]

    This paper proposes a spatial three degrees of freedom (DOF) parallel kinematic machine enhanced by a passive leg and a web-based remote control system. First, the geometric model of the parallel kinematic machine is addressed. In the mechanism, a fourth kinematic link-a passive link connecting the base center to the moving platform center-is introduced. Each of the three parallel limbs is actuated by one prismatic joint, respectively. The additional link has three passive DOF, namely two rotations around x and y axes and one translation along z axis. With the existence of this link, the unwanted motion of the tool (located in the moving platform) is constrained. The fourth link also enhances the global stiffness of the structure and distributes the torque from machining. With the kinematic model, a web-based remote control approach is applied. The concept of the web-based remote manipulation approach is introduced and the principles behind the method are explored in detail. Finally, a remote manipulation is demonstrated to the proposed structure using web-based remote control concept.

  • 10240.
    Zhang, Hong
    et al.
    University of Skövde, School of Life Sciences.
    Sun, Xiao-Feng
    Department of Biomedicine and Surgery, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
    Synnerstad, Ingrid
    Division of Dermatology, Department of Clinical and Experimental Medicine, Linköping University, Sweden.
    Rosdahl, Inger
    Division of Dermatology, Department of Clinical and Experimental Medicine, Linköping University, Sweden.
    Importance of FAS-1377, FAS-670 and FASL-844 Polymorphisms in Tumor Onset, Progression and Pigment Phenotypes of Swedish Patients With Melanoma: A Case-Control Analysis2007In: The Cancer Journal, ISSN 1528-9117, E-ISSN 1540-336X, Vol. 13, no 4, p. 233-237Article in journal (Refereed)
    Abstract [en]

    PURPOSE: Human skin melanoma at later stages usually has an extremely poor prognosis. It is of importance to search for biologic markers to identify and monitor individuals at risk for melanoma for early diagnosis and to avoid tumor progression. The FAS gene and its natural ligand (FASL) gene initiate the death signal cascade, playing a central role in the apoptotic signaling pathway and tumor growth and metastasis. PATIENTS AND METHODS: In this study, we analyzed polymorphisms in 229 patients with melanoma and 351 age- and gender-matched tumor-free individuals. Genomic DNAs were isolated from mononuclear cells in peripheral vein blood, and the polymorphisms were examined with polymerase chain reaction-restriction fragment length polymorphism techniques. Frequency in distribution of the polymorphisms was compared between the patients with melanoma and the healthy control subjects, and associations with patients' pigment phenotypes, age at diagnosis, and melanoma characteristics were analyzed. RESULTS AND CONCLUSIONS: The FAS-1377, FAS-670, and FASL-844 polymorphisms were not found to be markers of melanoma risk (P > 0.05). In patients with melanoma, frequencies of the FAS-1377, FAS-670, and FASL-844 polymorphisms were different between the patients aged <50 and > or =50 years (P < or = 0.025, P < or = 0.025, and P < or = 0.01). Moreover, the FAS-670 polymorphism correlated with tumor Breslow thickness (P < or = 0.01) and Clark level (P < or = 0.001) and was associated with tumors developing in sun-exposed locations (P < or = 0.001). FAS and FASL were not markers for melanoma risk but might be important in the development and progression of sun-induced melanoma independently of skin type.

  • 10241.
    Zhang, Hong
    et al.
    University of Skövde, School of Life Sciences. University of Skövde, The Systems Biology Research Centre.
    Wang, Da-Wei
    University of Skövde, School of Life Sciences. University of Skövde, The Systems Biology Research Centre. Department of Stomatology, The Third Hospital of Hebei Medical University, Hebei, China.
    Adell, Gunnar
    Department of Oncology, Karolinska University Hospital, Karolinska, Sweden.
    Sun, Xiao-Feng
    Division of Oncology, Department of Clinical and Experimental Medicine, Faculty of Heath Science, Linköping University, Sweden .
    WRAP53 is an independent prognostic factor in rectal cancer- a study of Swedish clinical trial of preoperative radiotherapy in rectal cancer patients2012In: BMC Cancer, ISSN 1471-2407, E-ISSN 1471-2407, Vol. 12, p. 294-Article in journal (Refereed)
    Abstract [en]

    Background: Expression of WRAP53 protein has oncogenic properties and it is up regulated in several types of tumors. Methods: We examined expression of WRAP53 protein in rectal cancers and analyzed its relationship to the response to preoperative radiotherapy and patient survival. The WRAP53 protein was examined by immunohistochemistry in normal mucosa, primary tumors and lymph node metastases from 143 rectal cancer patients participated in a Swedish clinical trial of preoperative radiotherapy. Results: Frequency of WRAP53 protein expression was increased in primary rectal cancer compared to the normal mucosa (p < 0.05). In non-radiotherapy group positive WRAP53 in primary tumors (p = 0.03, RR, 3.73, 95% CI, 1.13-11.89) or metastases (p = 0.01, RR, 4.11, 95% CI, 1.25-13.14), was associated with poor prognosis independently of stages and differentiations. In radiotherapy group, positive WRAP53 in the metastasis correlated with better survival (p = 0.04). An interaction analysis showed that the correlations of WRAP53 with the prognostic significance with and without radiotherapy in the metastasis differed (p = 0.01). In the radiotherapy group, expression of WRAP53 in metastases gave a better outcome (p = 0.02, RR, 0.32, 95% CI, 0.13-0.84), and an interaction analysis showed significance between the two groups (p = 0.01). Conclusion: WRAP53 may be a new biomarker used to predict prognosis and to select suitable patients for preoperative radiotherapy.

  • 10242.
    Zhang, Hong
    et al.
    University of Skövde, School of Life Sciences. University of Skövde, The Systems Biology Research Centre.
    Widegren, Emma
    Linkoping Univ, Dept Oncol, Inst Clin & Expt Med, Linkoping, Sweden .
    Wang, Da-Wei
    Hebei Med Univ, Hosp 3, Dept Stomatol, Shijiazhuang, Peoples R China.
    Sun, Xiao-Feng
    Linkoping Univ, Dept Oncol, Inst Clin & Expt Med, Linkoping, Sweden .
    SPARCL1: a potential molecule associated with tumor diagnosis, progression and prognosis of colorectal cancer2011In: Tumor Biology, ISSN 1010-4283, E-ISSN 1423-0380, Vol. 32, no 6, p. 1225-1231Article in journal (Refereed)
    Abstract [en]

    We investigated whether SPARCL1 played an essential role in tumor initiation, formation and progression of colorectal carcinomas. In this study, we examined expression of SPARCL1 protein in the normal colorectal mucosa, adjacent normal mucosa and primary and lymph node metastases from colorectal cancer patients. In matched patients, we found that SPARCL1 was negative in the distant normal colorectal mucosa, weakly expressed in the adjacent normal mucosa, strongly expressed in primary colorectal adenocarcinomas and slightly expressed in their lymph node metastases. A similar pattern was observed in the SPARCL1 expression from our series of non-matched colorectal cancer patients. The strongest expression and highest frequency of the SPARCL1 protein were found in the primary cancers. Interestingly, in the primary tumors, the frequency of SPARCL1 expression was significantly increased from the Dukes' A to Dukes' B tumors and then decreased gradually from the Dukes' B to C and D tumors. There was no difference in the intensity of SPARCL1 expression between the central areas and invasion margins of the primary tumors. Moreover, the SPARCL1 protein was more strongly expressed in the highly differentiated tumors than the lower differentiated ones. The patients with positive expression of SPARCL1 in their tumors had worse prognosis than the patients with SPARCL1-negative ones, even after the analyses by Multivariate and Interaction method. Expression of SPARCL1 protein might be a valuable biomarker for early diagnosis in colorectal cancers and further predicting patients' prognosis.

  • 10243.
    Zhang, Qiongyan
    University of Skövde, School of Technology and Society.
    The Consumption Function of Luxury Goods2009Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    The goal of this thesis will be to formulate an economic model that exposes the relationship between consumption of luxury goods and selected factors which includes advertising, disposable income, interest rate, price index and stock premium.

    By building the Multiple Linear Regressions model to formulate the consumption function and using the Ordinary Least Squares (OLS) as the method, it becomes apparent that advertising, disposable income and the previous quarter´s disposable income are the major variables to affect luxury good consumption, of all the factors. Furthermore, the previous quarter´s disposable income has a slightly higher effect than the current one on luxury consumption. Similar studies, which focus on luxury items, have proposed models that test a single or a few variables at a time, and others that concentrate on durable goods have a wide range of variables to examine. I attempt to combine both in my model to test luxury consumption with a wide range of variables.

  • 10244.
    Zhang, Xiaoyang
    et al.
    Faculty of Engineering, Environment and Computing, Coventry University, Coventry, United Kingdom.
    Lu, Xin
    Faculty of Engineering, Environment and Computing, Coventry University, Coventry, United Kingdom.
    Wang, Sheng
    Faculty of Engineering, Environment and Computing, Coventry University, Coventry, United Kingdom.
    Wang, Wei
    University of Skövde, School of Engineering Science. University of Skövde, The Virtual Systems Research Centre.
    Li, Weidong
    Faculty of Engineering, Environment and Computing, Coventry University, Coventry, United Kingdom.
    A multi-sensor based online tool condition monitoring system for milling process2018In: Procedia CIRP, ISSN 2212-8271, E-ISSN 2212-8271, Vol. 72, p. 1136-1141Article in journal (Refereed)
    Abstract [en]

    Tool condition monitoring has been considered as one of the key enabling technologies for manufacturing optimization. Due to the high cost and limited system openness, the relevant developed systems have not been widely adopted by industries, especially Small and Medium-sized Enterprises. In this research, a cost-effective, wireless communication enabled, multi-sensor based tool condition monitoring system has been developed. Various sensor data, such as vibration, cutting force and power data, as well as actual machining parameters, have been collected to support efficient tool condition monitoring and life estimation. The effectiveness of the developed system has been validated via machining cases. The system can be extended to wide manufacturing applications.

  • 10245.
    Zhang, Zhi-Yong
    et al.
    Linkoping Univ, Inst Clin & Expt Med, Dept Oncol, S-58185 Linkoping, Sweden / Tangshan Gongren Hosp, Dept Pathol, Tangshan, Peoples R China / Hebei Med Univ, Hosp 1, Lab Ctr, Shijiazhuang, Peoples R China.
    Zhang, Hong
    University of Skövde, School of Life Sciences. University of Skövde, The Systems Biology Research Centre.
    Adell, Gunnar
    Karolinska Univ Hosp, Dept Oncol, Stockholm, Sweden.
    Sun, Xiao-Feng
    Linkoping Univ, Inst Clin & Expt Med, Dept Oncol, S-58185 Linkoping, Sweden.
    Endosialin expression in relation to clinicopathological and biological variables in rectal cancers with a Swedish clinical trial of preoperative radiotherapy2011In: BMC Cancer, ISSN 1471-2407, E-ISSN 1471-2407, Vol. 11, p. Artikelnr 89-Article in journal (Refereed)
    Abstract [en]

    Background: The importance of changes in tumour-associated stroma for tumour initiation and progression has been established. Endosialin is expressed in fibroblasts and pericytes of blood vessels in several types of tumours, and is involved in the progression of colorectal cancer. In order to see whether endosialin was related to radiotherapy (RT) response, and clinicopathological and biological variables, we investigated endosialin expression in rectal cancers from the patients who participated in a Swedish clinical trial of preoperative RT. Methods: Endosialin was immunohistochemically examined in normal mucosa, including distant (n = 72) and adjacent (n = 112) normal mucosa, and primary tumours (n = 135). Seventy-three of 135 patients received surgery alone and 62 received additional preoperative RT. Results: Endosialin expression in the stroma increased from normal mucosa to tumour (p < 0.0001) both in RT and non-RT group. In the RT group, endosialin expression in the stroma was positively associated with expression of cyclooxygenase-2 (Cox-2) (p = 0.03), p73 (p = 0.01) and phosphates of regenerating liver (PRL) (p = 0.002). Endosialin expression in the tumour cells of both in the RT group (p = 0.01) and the non-RT group (p = 0.06) was observed more often in tumours with an infiltrative growth pattern than in tumours with an expansive growth pattern. In the RT group, endosialin expression in tumour cells was positively related to PRL expression (p = 0.02), whereas in the non-RT group, endosialin expression in tumour cells was positively related to p73 expression (p = 0.01). Conclusions: Endosialin expression may be involved in the progression of rectal cancers, and was related to Cox-2, p73 and PRL expression. However, a direct relationship between endosialin expression and RT responses in patients was not found.

  • 10246.
    Zhao, Zeng-Ren
    et al.
    Department of General Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, P.R. China.
    Zhang, Zhi-Yong
    Department of Oncology, Institute of Biomedicine and Surgery, Linköping University, Linköping, Sweden / Department of Pathology, Tangshan Gongren Hospital, Tangshan, P.R. China.
    Zhang, Hong
    Department of Dermatology, Institute of Biomedicine and Surgery, Linköping University, Linköping, Sweden.
    Jiang, Li
    Department of Pathology, Tangshan Gongren Hospital, Tangshan, P.R. China.
    Wang, Ming-Wei
    Laboratory Centre, The First Hospital of Hebei Medical University, Shijiazhuang, P.R. China.
    Sun, Xiao-Feng
    Department of Oncology, Institute of Biomedicine and Surgery, Linköping University, Linköping, Sweden.
    Overexpression of Id-1 protein is a marker in colorectal cancer progression2008In: Oncology Reports, ISSN 1021-335X, E-ISSN 1791-2431, Vol. 19, no 2, p. 419-424Article in journal (Refereed)
    Abstract [en]

    Abstract: The inhibitor of differentiation/DNA binding 1 (Id-1), a negative regulator of basic helix-loop-helix transcription factors, plays an important role in the regulation of cell proliferation and differentiation. We examined the Id-1 expression by immunohistochemistry in 9 adenomas, 79 primary colorectal adenocarcinomas matched with 40 adjacent normal mucosa specimens and its relationship with clinicopathological factors. The Id-1 expression was increased in the carcinoma compared to the adjacent normal mucosa either in the unmatched and matched samples or to the adenoma. There was no significant difference in the Id-1 expression between normal mucosa and adenoma. The Id-1 expression of carcinoma was increased from Dukes' stages A to B, to C and to D. The cases with lymph node metastasis had a higher rate of a stronger Id-1 expression than those without lymph node metastasis. In conclusion, Id-1 overexpression plays an important role in colorectal cancer progression.

  • 10247.
    Zhen, Rong
    et al.
    University of Skövde, School of Informatics. University of Skövde, The Informatics Research Centre. Merchant Marine College, Shanghai Maritime University, Shanghai, China.
    Riveiro, Maria
    University of Skövde, School of Informatics. University of Skövde, The Informatics Research Centre.
    Jin, Yongxing
    Merchant Marine College, Shanghai Maritime University, Shanghai, China.
    A novel analytic framework of real-time multi-vessel collision risk assessment for maritime traffic surveillance2017In: Ocean Engineering, ISSN 0029-8018, E-ISSN 1873-5258, Vol. 145, p. 492-501Article in journal (Refereed)
    Abstract [en]

    Multi-vessel collision risk assessment for maritime traffic surveillance is a key technique to ensure the safety and security of maritime traffic and transportation. This paper proposes a framework of real-time multi-vessel collision assessment that combines a spatial clustering process (DBSCAN) for detecting clusters of encounter vessels and a multi-vessel collision risk index model for encounter vessels within each cluster from the large amounts of monitored vessels in a surveyed sea area. First, the vessels monitored are clustered using DBSCAN to obtain the clusters of encounter vessels, filtering out the relatively safe vessels. Then, the dynamic motion relation between encounter vessels within each cluster is modeled to obtain DCPA and TCPA. The semantic and mathematical relationship of vessel collision risk index for each cluster of encounter vessels with DCPA and TCAP is constructed using a negative exponential function. To illustrate the effectiveness of the framework proposed, an experimental case study has been carried out within the west coastal waters of Sweden. The results show that our framework is effective and efficient at detecting and ranking collision risk indexes between encounter vessels within each duster, which allows an automatic risk prioritization of encounter vessels for further investigation by operators. Hence, this framework can improve the safety and security of vessel traffic transportation and reduce the loss of lives and property.

  • 10248.
    Zhou, Bo
    et al.
    German Research Center for Artificial Intelligence, Kaiserslautern, Germany / University of Kaiserslautern, Kaiserslautern, Germany.
    Cruz, Heber Zurian
    German Research Center for Artificial Intelligence, Kaiserslautern, Germany / University of Kaiserslautern, Kaiserslautern, Germany.
    Atefi, Seyed Reza
    Swedish School of Textiles, University of Borås, Borås, Sweden.
    Billing, Erik
    University of Skövde, School of Informatics. University of Skövde, The Informatics Research Centre.
    Seoane, Fernando
    Inst. for Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden / Dept. Biomedical Engineering, Karolinska University Hospital, Stockholm, Sweden / Swedish School of Textiles, University of Borås, Borås, Sweden.
    Lukowicz, Paul
    German Research Center for Artificial Intelligence, Kaiserslautern, Germany / University of Kaiserslautern, Kaiserslautern, Germany.
    TouchMe: Full-textile Touch Sensitive Skin for Encouraging Human-Robot Interaction2017Conference paper (Refereed)
  • 10249.
    Zhou, Bo
    et al.
    German Research Center for Artificial Intelligence, Kaiserslautern, Germany.
    Velez Altamirano, Carlos Andres
    Department Computer Science, University of Kaiserslautern, Kaiserslautern, Germany.
    Cruz Zurian, Heber
    Department Computer Science, University of Kaiserslautern, Kaiserslautern, Germany.
    Atefi, Seyed Reza
    Swedish School of Textiles, University of Borås, Borås, Sweden.
    Billing, Erik
    University of Skövde, School of Informatics. University of Skövde, The Informatics Research Centre.
    Seoane Martinez, Fernando
    Swedish School of Textiles, University of Borås, Borås, Sweden / Institute for Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden / Department Biomedical Engineering, Karolinska University Hospital, Stockholm, Sweden.
    Lukowicz, Paul
    German Research Center for Artificial Intelligence, Kaiserslautern, Germany / Department Computer Science, University of Kaiserslautern, Kaiserslautern, Germany.
    Textile Pressure Mapping Sensor for Emotional Touch Detection in Human-Robot Interaction2017In: Sensors, ISSN 1424-8220, E-ISSN 1424-8220, Vol. 17, no 11, article id 2585Article in journal (Refereed)
    Abstract [en]

    In this paper, we developed a fully textile sensing fabric for tactile touch sensing as the robot skin to detect human-robot interactions. The sensor covers a 20-by-20 cm2 area with 400 sensitive points and samples at 50 Hz per point. We defined seven gestures which are inspired by the social and emotional interactions of typical people to people or pet scenarios. We conducted two groups of mutually blinded experiments, involving 29 participants in total. The data processing algorithm first reduces the spatial complexity to frame descriptors, and temporal features are calculated through basic statistical representations and wavelet analysis. Various classifiers are evaluated and the feature calculation algorithms are analyzed in details to determine each stage and segments’ contribution. The best performing feature-classifier combination can recognize the gestures with a 93.3% accuracy from a known group of participants, and 89.1% from strangers.

  • 10250.
    Zhou, Jiayang
    University of Skövde, School of Informatics.
    Guiding operators' attention with the help of a visual aid system2019Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    In the cutting age of industrial 4.0, automation has developed rapidly in all aspects. The emergence of the modern industrial control room has provided a new horizon to the large operation. However, the problem facing the operators is too many screens that they need to monitor at the same time which could result in fatal mistakes such as missing important alerts or failing to act on important information. With that being said, this thesis explores the possibilities of developing a visual aid system to help guide operators’ attention. With the knowledge gained from a literature review and previous efforts from ABB, a visual aid system has been developed with implementations such as unreadable screen and blinking cue guiding the operators’ attention. An experiment to evaluate the solution has also been designed and conducted with 29 participants. Both quantitative data and qualitative data have been collected and analyzed. The results suggest a strong benefit in using such a visual aid to help guide operators’ attention.

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