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Infectious Diseases: Helicobacter pylori
University of Skövde, School of Bioscience. University of Skövde, The Systems Biology Research Centre. Unilabs AB. (Infektionsbiologi, Infection Biology)ORCID iD: 0000-0001-7684-5702
Karolinska Institute and Science for Life Laboratory.
2015 (English)In: Reference Module in Biomedical Sciences, Elsevier, 2015Chapter in book (Other academic)Text
Abstract [en]

Abstract Helicobacter pylori infection is one of the most common human infections in the world. The bacteria cause peptic ulcer disease and their infection is an important factor for gastric cancer development. The bacteria are transmitted from person to person within families, with young children most often infected. The bacteria reside in the stomach for a lifetime if untreated by antimicrobial agents. Many virulence factors are known that contribute to the persistence of the bacteria in the stomach, and the bacteria harbors a pathogenicity island in its genome. The discovery of H. pylori as a cause of gastritis in the stomach led to the Nobel Prize in Physiology or Medicine 2005.

Place, publisher, year, edition, pages
Elsevier, 2015.
Keyword [en]
Antibiotics, cagA, Diagnostic, Eradication, Gastric cancer, Helicobacter, Helicobacter pylori, Pathogenicity, Peptic ulcer disease, Transmission, Urease, vacA, Virulence
National Category
Microbiology in the medical area
Identifiers
URN: urn:nbn:se:his:diva-12394DOI: 10.1016/B978-0-12-801238-3.98785-3ISBN: 978-0-12-801238-3 OAI: oai:DiVA.org:his-12394DiVA: diva2:935101
Available from: 2016-06-10 Created: 2016-06-10 Last updated: 2016-09-22Bibliographically approved

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