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The effects of endurance training in persons with a hereditary myosin myopathy
Department of Clinical Neuroscience-Rehabilitation Medicine, University of Göteborg, Sahlgrenska Hospital, Göteborg, Sweden.
Department of Pediatrics, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.
Department of Pathology, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.ORCID iD: 0000-0001-8854-5213
Department of Pathology, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.
2004 (English)In: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404, Vol. 110, no 2, 80-86 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: To evaluate muscle performance and its consequences in eight individuals with a hereditary myopathy and the effects of an 8-week endurance training program.

MATERIAL AND METHODS: Handgrip, muscle strength and endurance and oxygen consumption by breath-by-breath analysis during a stepless bicycle ergonometer test were evaluated. Walking, balance test and activities of daily living (ADL) were assessed, and a questionnaire for activity level and perceived symptoms was used. The design was a before-after trial in comparison with data from a control population, bicycling at 70% of maximal workload, 30 min/day, 5 days/week for 8 weeks.

RESULTS: The subjects were weaker than age-matched controls. After training, the peak watt increased by almost 20% (P < 0.05). Muscle strength (flexion/extension) and isometric endurance (40% of maximum at 60 degrees ) did not change significantly. The average self-selected walking speed increased significantly (P < 0.05) from 1.25 to 1.45 m/s. Compliance was excellent and no serious adverse events occurred.

CONCLUSION: Endurance training seems to function for this myopathy.

Place, publisher, year, edition, pages
John Wiley & Sons, 2004. Vol. 110, no 2, 80-86 p.
National Category
Research subject
Medical sciences
URN: urn:nbn:se:his:diva-11982DOI: 10.1111/j.1600-0404.2004.00282.xISI: 000223064200002PubMedID: 15242414ScopusID: 2-s2.0-3843062506OAI: oai:DiVA.org:his-11982DiVA: diva2:907135
Available from: 2016-02-26 Created: 2016-02-26 Last updated: 2016-03-08Bibliographically approved

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