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The course of health related quality of life in postmenopausal women with breast cancer from breast surgery and up to five years post-treatment
University of Skövde, School of Life Sciences. Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Division of Nursing, Stockholm, Sweden.ORCID iD: 0000-0003-0976-531X
Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Division of Nursing, Stockholm, Sweden / Umeå University, Department of Nursing, Umeå, Sweden.
The Sahlgrenska Academy, University of Gothenburg, Institute of Health and Care Sciences, Gothenburg, Sweden.
Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Division of Nursing, Stockholm, Sweden.
2013 (English)In: Breast, ISSN 0960-9776, E-ISSN 1532-3080, Vol. 22, no 5, 952-957 p.Article in journal (Refereed) Published
Abstract [en]

Background: Previous studies include too few patients over 70 years to be able to assess treatment effects on Health Related Quality Of Life (HRQOL) in the older age group. We aimed to follow HRQOL in postmenopausal women (55-80 years) with breast cancer receiving adjuvant treatment, until five years post-treatment, and compare with a general population. Patients and methods: The patient sample included 150 women (adjuvant CT n=75 and RT n=75) and two reference samples from the Swedish SF-36 norm database. Results: Data from baseline showed significantly higher levels of physical functioning and general health among the patients compared to the reference sample, and significantly lower levels of bodily pain, emotional role functioning and mental health. Longitudinal analyses showed significant changes in all scales, and three different patterns (a decrease-stable, a decrease-increase, and a stable- increase pattern) were identified. Conclusion: Postmenopausal women seem to successfully manage the effects of adjuvant treatment on HRQOL. © 2013 Elsevier Ltd.

Place, publisher, year, edition, pages
Elsevier, 2013. Vol. 22, no 5, 952-957 p.
Keyword [en]
Adjuvant treatment, Breast cancer, HRQOL, Longitudinal, Postmenopausal, SF-36, adult, aged, article, breast surgery, cancer adjuvant therapy, cancer chemotherapy, cancer pain, cancer radiotherapy, controlled study, cross-sectional study, emotion, factual database, female, follow up, health status, human, longitudinal study, major clinical study, mental health, pain assessment, physical activity, population research, postmenopause, postoperative period, priority journal, quality of life, standard
National Category
Medical and Health Sciences
Research subject
Medical sciences
Identifiers
URN: urn:nbn:se:his:diva-8612DOI: 10.1016/j.breast.2013.05.002ISI: 000324516800063PubMedID: 23751861ScopusID: 2-s2.0-84884139362OAI: oai:DiVA.org:his-8612DiVA: diva2:661088
Available from: 2013-10-31 Created: 2013-10-31 Last updated: 2015-04-22Bibliographically approved

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