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Health-related quality of life during adjuvant treatment for breast cancer among postmenopausal women
The Sahlgrenska Academy at Göteborg University, Institute of Health and Care Sciences, Göteborg, Sweden / Department of Oncology, Division of Selected Clinical Specialties, Sahlgrenska University Hospital, Göteborg, Sweden.
The Sahlgrenska Academy at Göteborg University, Institute of Health and Care Sciences, Göteborg, Sweden.
The Sahlgrenska Academy at Göteborg University, Institute of Health and Care Sciences, Göteborg, Sweden / Department of Oncology, Southern Älvsborg Hospital, Borås, Sweden.
The Sahlgrenska Academy at Göteborg University, Institute of Health and Care Sciences, Göteborg, Sweden / Department of Health Science, Mid Sweden University, Östersund, Sweden.
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2008 (English)In: European Journal of Oncology Nursing, ISSN 1462-3889, E-ISSN 1532-2122, Vol. 12, no 3, 180-189 p.Article in journal (Refereed) Published
Abstract [en]

The purpose of the present study was twofold: first, to describe changes of Health-Related Quality of Life (HRQoL) during the adjuvant treatment among postmenopausal women with breast cancer; second, in the same population to identify the best predictors of Overall Quality of Life (QoL) after treatment, from perceived functioning, symptoms, emotional distress and clinical/demographic variables measured at baseline. The study group was 150 women (>= 55 years of age) scheduled for adjuvant chemotherapy (CT, n=75) or radiotherapy (RT, n=75). They were examined before (baseline), during and after completing the treatment. Data about QoL, perceived functioning, symptoms and emotional distress were collected with the European Organisation for Research and Treatment of Cancer (EORTC)-QLQ-C30, BR23 and Hospital Anxiety and Depression Scale (HADS) questionnaires. The general finding was that the adjuvant treatments were associated with decrease in overall QoL, physical and role functioning, anxiety and body image, as well as with increase in fatigue, dyspnoea, pain, nausea/vomiting, constipation and systemic therapy side effects measured over time. For women receiving CT, better emotional functioning and less pain at baseline predicted better overall QoL at the end of the treatment. For women receiving RT, better physical and emotional functioning, less breast symptoms and lower tumour stage at baseline predicted better overall QoL at the end of the treatment. (c) 2008 Elsevier Ltd. All rights reserved.

Place, publisher, year, edition, pages
Elsevier, 2008. Vol. 12, no 3, 180-189 p.
Keyword [en]
quality of life, chemotherapy, radiotherapy, breast cancer, elderly
Identifiers
URN: urn:nbn:se:his:diva-7060DOI: 10.1016/j.ejon.2008.01.005ISI: 000257838200002PubMedID: 18343197Scopus ID: 2-s2.0-45449086029OAI: oai:DiVA.org:his-7060DiVA: diva2:601088
Available from: 2013-01-28 Created: 2013-01-28 Last updated: 2013-01-28

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