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Vitamin and mineral status in elderly patients with chronic obstructive pulmonary disease
Department of Internal Medicine, Sahlgrenska Academy at Göteborg University, Göteborg, Sweden.
Department of Internal Medicine, Sahlgrenska Academy at Göteborg University, Göteborg, Sweden.
University of Skövde, School of Life Sciences.
Univ Gothenburg, Sahlgrenska Acad, Dept Clin Nutr, Gothenburg, Sweden.
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2007 (English)In: Clinical Respiratory Journal, ISSN 1752-6981, Vol. 1, no 1, 23-29 p.Article in journal (Refereed) Published
Abstract [en]

Introduction: Eating problems are common in patients with chronic obstructive pulmonary disease (COPD), and intake of micronutrients might be lower than recommended. Objective: To study dietary intake, serum and urinary concentration of trace elements and vitamins in elderly underweight patients with established severe COPD. Methods: Outpatients at a university clinic for lung medicine, with COPD, 70-85 years old, with no other serious disease, and with a body mass index (BMI) of similar to 20 kg/m(2) and an FEV(1) of < 50 % predicted were recruited. Body composition and bone density were evaluated with dual energy X-ray absorptiometry. Dietary intake was studied by a trained dietitian using diet-history interview. Blood and urine samples were analysed for various vitamins and trace elements. Results: Seventeen of 30 recruited patients took part. Osteoporosis or osteopaenia was found in 16 patients. Dietary intake of energy and macronutrients was in line with recommendations for healthy individuals. Intake of protein did not meet recommendations for COPD patients. Intake of polyunsaturated fatty acids was lower than recommended and intake of saturated fatty acids was higher than recommended. Mean intake of vitamin D and folic acid was far below recommendations. Serum concentrations for folic acid and methylmalonate and plasma concentrations for homocysteine were below normal in several patients. Conclusion: Intake of vitamin D and calcium is often low in older COPD patients, which might contribute to osteoporosis. Low intake of folic acid might also be a problem. The results support prophylaxis with calcium, vitamin D and folic acid.

Place, publisher, year, edition, pages
Blackwell Publishing, 2007. Vol. 1, no 1, 23-29 p.
Keyword [en]
COPD, malnutrition, nutritional status, trace elements, vitamins
National Category
Medical and Health Sciences
Research subject
Medical sciences
Identifiers
URN: urn:nbn:se:his:diva-6892DOI: 10.1111/j.1752-699X.2007.00003.xISI: 000257139300004PubMedID: 20298274Scopus ID: 2-s2.0-77955078845OAI: oai:DiVA.org:his-6892DiVA: diva2:575190
Available from: 2012-12-07 Created: 2012-12-07 Last updated: 2013-04-11Bibliographically approved

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