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Outcome for invasive Staphylococcus aureus infections
Department of Infectious Diseases, Skaraborg Hospital, Skövde, Sweden.
University of Skövde, School of Life Sciences.
Research and Development Centre, Skaraborg Hospital, Skövde, Sweden.
2008 (English)In: European Journal of Clinical Microbiology and Infectious Diseases, ISSN 0934-9723, E-ISSN 1435-4373, Vol. 27, no 9, 839-848 p.Article in journal (Refereed) Published
Abstract [en]

We report a survey of invasive Staphylococcus aureus (ISA) infections concerning outcome variables such as mortality, recurrence and residual symptoms. A prospective, population-based study of all cases of ISA was conducted in the catchment area of Skaraborg Hospital (population 255,109) in western Sweden during the period from 1st March 2003 to 28th February 2005. One hundred and fifty-seven patients were included. Recurrences were seen in 13 cases (9.3%). Thirty patients (19.1%) died during the first 28 days. Mortality rates for complicated bacteraemia and severe sepsis were 32% and 54%, respectively. Older patients (> 65 years of age), patients with concomitant heart disease and patients with endovascular infections all suffered higher mortality. Line-associated infections had a higher recurrence rate. Residual symptoms were common, with 34% of the living patients reporting incomplete recovery. Accessory gene regulator (agr) type within the bacteria did not affect disease presentation. We conclude that ISA infections are of major medical importance, with high rates of mortality (19.1%), recurrence (9.3%) and residual functional impairment (34%).

Place, publisher, year, edition, pages
Springer, 2008. Vol. 27, no 9, 839-848 p.
National Category
Medical and Health Sciences
Research subject
Medical sciences
Identifiers
URN: urn:nbn:se:his:diva-6858DOI: 10.1007/s10096-008-0515-5ISI: 000258453000010PubMedID: 18449584Scopus ID: 2-s2.0-49649088176OAI: oai:DiVA.org:his-6858DiVA: diva2:573066
Available from: 2012-11-29 Created: 2012-11-28 Last updated: 2016-01-25Bibliographically approved

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CiteExportLink to record
Permanent link

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Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
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