Road traffic injuries are major public health social and economic problem. In China road traffic injuries are increasing rapidly. Objective of the study was to assess the risk factors for road traffic injuries and the relationship between the individual and environmental factors and the severity of injury in a designated Safe Community in Shanghai, China. Data were retrieved from a Safe Community surveillance system including hospital, police and fire brigade records. Chi-square test and multivariate logistic regression were used. Total 568 was injured due to road accidents in 2008 (43% were mild injured and 9% severely injured).Violation of traffic rule was major problem among drivers of motorized vehicles. Police has identified 15 major causes of road accidents. Age over 45 years and cloudy/rainy road conditions were major cause of accidents at the individual and environmental level factors. Findings are important for policy makers and Safe Community planning.