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Deriving Genetic Networks from Gene Expression Data and Prior Knowledge
University of Skövde, Department of Computer Science.
2001 (English)Independent thesis Advanced level (degree of Master (One Year))Student thesis
Abstract [en]

In this work three different approaches for deriving genetic association networks were tested. The three approaches were Pearson correlation, an algorithm based on the Boolean network approach and prior knowledge. Pearson correlation and the algorithm based on the Boolean network approach derived associations from gene expression data. In the third approach, prior knowledge from a known genetic network of a related organism was used to derive associations for the target organism, by using homolog matching and mapping the known genetic network to the related organism. The results indicate that the Pearson correlation approach gave the best results, but the prior knowledge approach seems to be the one most worth pursuing

Place, publisher, year, edition, pages
Skövde: Institutionen för datavetenskap , 2001. , p. 86
Keywords [en]
Genetic networks, Homology, Gene expression data, Correlation measurement, Boolean network
National Category
Bioinformatics and Systems Biology
Identifiers
URN: urn:nbn:se:his:diva-589OAI: oai:DiVA.org:his-589DiVA, id: diva2:2976
Presentation
(English)
Uppsok
Life Earth Science
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Available from: 2008-01-25 Created: 2008-01-25 Last updated: 2009-11-18

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CiteExportLink to record
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Citation style
  • apa
  • apa-cv
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
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  • de-DE
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  • Other locale
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Output format
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