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Classification of information fusion methods in systems biology
University of Skövde, The Systems Biology Research Centre. University of Skövde, School of Life Sciences.
University of Skövde, The Systems Biology Research Centre. University of Skövde, School of Life Sciences.
University of Skövde, The Systems Biology Research Centre. University of Skövde, School of Life Sciences.
2009 (English)In: In Silico Biology, ISSN 1386-6338, Vol. 9, no 3, 65-76 p.Article, review/survey (Refereed) Published
Abstract [en]

Biological systems are extremely complex and often involve thousands of interacting components. Despite all efforts, many complex biological systems are still poorly understood. However, over the past few years high-throughput technologies have generated large amounts of biological data, now requiring advanced bioinformatic algorithms for interpretation into valuable biological information. Due to these high-throughput technologies, the study of biological systems has evolved from focusing on single components (e.g. genes) to encompassing large sets of components (e.g. all genes in an entire genome), with the aim to elucidate their interdependences in various biological processes. In addition, there is also an increasing need for integrative analysis, where knowledge about the biological system is derived by data fusion, using heterogeneous data sets as input. We here review representative examples of bioinformatic methods for fusion-oriented interpretation of multiple heterogeneous biological data, and propose a classification into three categories of tasks that they address: data extraction, data integration and data fusion. The aim of this classification is to facilitate the exchange of methods between systems biology and other information fusion application areas.

Place, publisher, year, edition, pages
IOS Press, 2009. Vol. 9, no 3, 65-76 p.
Keyword [en]
information fusion, data fusion, data integration, systems biology
National Category
Natural Sciences
Research subject
Natural sciences
Identifiers
URN: urn:nbn:se:his:diva-3298DOI: 10.3233/ISB-2009-0391PubMedID: 19795566Scopus ID: 2-s2.0-67649887352OAI: oai:DiVA.org:his-3298DiVA: diva2:227212
Available from: 2009-07-10 Created: 2009-07-10 Last updated: 2014-02-07Bibliographically approved

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Synnergren, JaneOlsson, BjörnGamalielsson, Jonas
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CiteExportLink to record
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Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
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  • en-US
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  • Other locale
More languages
Output format
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