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Interventioner för att minska hepatit C hos intravenösa drogmissbrukare: En strukturerad litteraturstudie
University of Skövde, School of Health Sciences.
2023 (Swedish)Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesisAlternative title
Interventions to reduce hepatitis C among intravenous drug users : A structured literature review (English)
Abstract [sv]

Introduktion: Hepatit C är en global folkhälsoutmaning, med 58 miljoner som lever med kronisk infektion. Sverige har cirka 45 000 diagnostiserade fall, med hög odiagnostiserade förekomst. Hepatit C är ofta asymtomatisk, kan leda till allvarliga leverkomplikationer och död. Hepatit C är en blodsmitta och den vanligaste smittvägen är delade injektionsnålar/utrustning därav är intravenösa missbrukare en grupp som ofta drabbas. Behandlingen mot hepatit C har utvecklats med effektiva antivirala läkemedel sedan 2014, och nya riktlinjer innebär behandling för alla, även de med pågående missbruk. Eliminering av hepatit C är ett globalt hälsomål och kopplas till FN:s Agenda 2030 för hållbar utveckling.

Syfte: Syftet med denna litteraturstudie var 1) beskriva olika interventioner som syftar till att eliminera hepatit C bland personer som missbrukar intravenösa droger genom att öka deltagande och 2) utvärdera interventionernas effekter avseende behandlingsdeltagande och behandlingsresultat.

Metod: En strukturerad litteraturstudie genomfördes med tematisk analys och deduktiv ansats som analysmetod. Resultatet baseras på tio artiklar som kvalitetsgranskades.

Resultat: Två teman identifierades; “Interventioner med fokus att öka delaktighet och deltagande av personer som injicerar droger i hepatit C-interventioner” och “Effekter på behandlingsdeltagande och behandlingsutfall”. Till dessa teman fanns även sex subteman. Resultaten visar att interventioner som inkluderar uppsökande verksamhet och integrerad vård har varit framgångsrika med att engagera personer som injicerar droger i hepatit C-vård.

Slutsats: Eliminering av hepatit C är ett globalt mål som kan uppnås genom effektiva interventioner. Framgångsrik implementering av interventioner kräver ökad tillgänglighet, minskade hinder och förtroendeskapande interaktion. Det krävs fortsatt utveckling och breddning av interventioner.

Abstract [en]

Introduction: Hepatitis C is a global public health challenge, with 58 million people living with a chronic infection. Sweden has approximately 45 000 diagnosed cases, with a high prevalence of undiagnosed cases. Hepatitis C is often asymptomatic, can lead to severe liver complications and death. Hepatitis C is a bloodborne infection, and the most common route of transmissions is through shared injection needles/equipment hence intravenous drugs users are at a higher risk. Treatment for hepatitis C has evolved with effective antiviral drugs since 2014, and new guidelines advocate treatment for everyone, including those with ongoing substance abuse. Eliminating hepatitis C is a global health goal linked to the UN’s Agenda 2030 for sustainable development.

Aim: The aim of this literature review was 1) to describe various interventions used to attempt the eradicate of hepatitis C among people who inject drugs, and 2) to evaluate the effects of the interventions in terms of treatment participation and treatment outcomes.

Method: A structured literature review was conducted using thematic analysis with a deductive approach as the analysis method. The results are based on ten quality-reviewed articles.

Results: Two themes were identified: "Interventions with a focus on increasing involvement and participation of people who inject drugs in hepatitis C interventions" and "Effects on treatmeant participation and treatment outcomes." Six subthemes also emerged within these themes. The results indicate that interventions involving outreach and integrated care have been successful in engaging people who inject drugs in hepatitis C care.

Conclusion: Elimination of hepatitis C is a global goal achievable through effective interventions. Successful implementation requires increased accessibility, reduced barriers, and trust-building interaction. Continued development and expansion of interventions are necessary.

Place, publisher, year, edition, pages
2023. , p. 44
Keywords [en]
Hepatitis C, eradication, intravenous drug users, interventions, participation
Keywords [sv]
Hepatit C, eliminering, intravenösa drogmissbrukare, intervention, deltagande
National Category
Public Health, Global Health and Social Medicine
Identifiers
URN: urn:nbn:se:his:diva-23869OAI: oai:DiVA.org:his-23869DiVA, id: diva2:1859860
Subject / course
Public Health Science
Educational program
Public Health Science: Infection Prevention and Control - Master’s Programme 60 ECTS
Supervisors
Examiners
Available from: 2024-05-22 Created: 2024-05-22 Last updated: 2025-02-20Bibliographically approved

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