Högskolan i Skövde

his.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • apa-cv
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Association of alcohol use with years lived without major chronic diseases: A multicohort study from the IPD-Work consortium and UK Biobank
Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland ; Faculty of Social Sciences, University of Tampere, Finland ; Finnish Institute of Occupational Health, Helsinki, Finland.ORCID iD: 0000-0001-5181-2402
Department of Epidemiology and Public Health, University College London, UK.
Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland ; Department of Public Health, University of Turku and Turku University Hospital, Finland ; Centre for Population Health Research, University of Turku and Turku University Hospital, Finland.
National Research Centre for the Working Environment, Copenhagen, Danmark.
Show others and affiliations
2022 (English)In: The Lancet Regional Health - Europe, ISSN 2666-7762, Vol. 19, article id 100417Article in journal (Refereed) Published
Abstract [en]

Background Heavy alcohol consumption increases the risk of several chronic diseases. In this multicohort study, we estimated the number of life-years without major chronic diseases according to different characteristics of alcohol use.

Methods In primary analysis, we pooled individual-level data from up to 129,942 adults across 12 cohort studies with baseline data collection on alcohol consumption, drinking patterns, and history between 1986 and 2005 (the IPD-Work Consortium). Self-reported alcohol consumption was categorised according to UK guidelines - non-drinking (never or former drinkers); moderate consumption (1-14 units); heavy consumption (>14 units per week). We further subdivided moderate and heavy drinkers by binge drinking pattern (alcohol-induced loss of consciousness). In addition, we assessed problem drinking using linked data on hospitalisations due to alcohol abuse or poisoning. Follow-up for chronic diseases for all participants included incident type 2 diabetes, coronary heart disease, stroke, cancer, and respiratory disease (asthma and chronic obstructive pulmonary disease) as ascertained via linkage to national morbidity and mortality registries, repeated medical examinations, and/or self-report. We estimated years lived without any of these diseases between 40 and 75 years of age according to sex and characteristics of alcohol use. We repeated the main analyses using data from 427,621 participants in the UK Biobank cohort study.

Findings During 1.73 million person-years at risk, 22,676 participants in IPD-Work cohorts developed at least one chronic condition. From age 40 to 75 years, never-drinkers [men: 29.3 (95%CI 27.9-30.8) years, women 29.8 (29.2 - 30.4) years)] and moderate drinkers with no binge drinking habit [men 28.7 (28.4-29.0) years, women 29.6 (29.4-29.7) years] had the longest disease-free life span. A much shorter disease-free life span was apparent in participants who experienced alcohol poisoning [men 23.4 (20.9-26.0) years, women 24.0 (21.4-26.5) years] and those with self-reported heavy overall consumption and binge drinking [men: 26.0 (25.3-26.8), women 27.5 (26.4 - 28.5) years]. The pattern of results for alcohol poisoning and self-reported alcohol consumption was similar in UK Biobank. In IPD-Work and UK Biobank, differences in disease-free years between self-reported moderate drinkers and heavy drinkers were 1.5 years or less.

Interpretation Individuals with alcohol poisonings or heavy self-reported overall consumption combined with a binge drinking habit have a marked 3- to 6-year loss in healthy longevity. Differences in disease-free life between categories of self-reported weekly alcohol consumption were smaller.

Place, publisher, year, edition, pages
Elsevier, 2022. Vol. 19, article id 100417
Keywords [en]
Alcohol consumption, Binge drinking, Disease free life years, Chronic diseases
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Research on Citizen Centered Health, University of Skövde (Reacch US)
Identifiers
URN: urn:nbn:se:his:diva-21730DOI: 10.1016/j.lanepe.2022.100417ISI: 000836548300003PubMedID: 35664051Scopus ID: 2-s2.0-85131418496OAI: oai:DiVA.org:his-21730DiVA, id: diva2:1690363
Funder
NordForskAcademy of Finland
Note

CC BY 4.0

Corresponding author at: Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Tukholmankatu 8B, FI-00014 Helsingin yliopisto, Helsinki, Finland. E-mail address: solja.nyberg@helsinki.fi (S.T. Nyberg).

Funding Medical Research Council, National Institute on Aging, NordForsk, Academy of Finland, Finnish Work Environment Fund.

Available from: 2022-08-25 Created: 2022-08-25 Last updated: 2023-12-04Bibliographically approved

Open Access in DiVA

fulltext(1269 kB)118 downloads
File information
File name FULLTEXT01.pdfFile size 1269 kBChecksum SHA-512
a618eb378b6bc83ef6acab1cf7456bbdb6b0888ee95aed970a7812fb40c6a363abf2bc102dd9e2126813a81d99c5ad389e915fed7118228ad71d7e5bc9c9607d
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMedScopus

Authority records

Suominen, Sakari

Search in DiVA

By author/editor
Nyberg, Solja T.Suominen, Sakari
By organisation
School of Health SciencesDigital Health Research (DHEAR)
Public Health, Global Health, Social Medicine and Epidemiology

Search outside of DiVA

GoogleGoogle Scholar
Total: 118 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 148 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • apa-cv
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf