Effect of topical local anaesthesia on injection pain associated with administration of sterile water injections - a randomized controlled trialShow others and affiliations
2022 (English)In: BMC Anesthesiology, ISSN 1471-2253, E-ISSN 1471-2253, Vol. 22, no 1, article id 35
Article in journal (Refereed) Published
Abstract [en]
Background
Sterile water injections can provide effective pain relief during childbirth, particularly for low back pain related to childbirth. However, the pain associated administering the injections can negatively impact women’s impressions of the procedure. It may discourage women from considering repeat doses despite the quality of analgesia experienced. Determining strategies to reduce the pain related to the administration of sterile water injections would improve the acceptability of the technique. Therefore, the aim of this study was to evaluate the effect of topical local anesthesia on the pain associated with administration of sterile water injections.
Methods
The study was designed as a multi-arm single-blind, randomized, controlled trial and 120 female healthy students were randomly divided according to one of four groups. The Intervention group received sterile water injections with topical local anesthesia. Control group 1 received sterile water injections without topical local anesthesia, control group 2 received injections of isotonic saline 0.9% with topical local anesthesia and control group 3 received injections of isotonic saline 0.9% without topical local anesthesia. Pain Immediately after the injections and subsidence in pain were recorded using a visual analogue scale. Sensations in the injection area were reported 15 min and the day after the injections.
Results
The main finding of this study was that local anesthesia with EMLA® reduces the pain associated with the administration of intracutaneous sterile water injections. There was a significant difference in the self-assessed pain score immediately following the injections between the control (73.3 mm) and intervention groups (50.0 mm), p = 0.001. No adverse side effects were reported.
Conclusion
Local anesthesia with EMLA® reduces the pain associated with intracutaneous administration of sterile water injections.
Place, publisher, year, edition, pages
Springer Nature, 2022. Vol. 22, no 1, article id 35
Keywords [en]
Pain, Pain relief, Sterile water injections, Randomized controlled trial, Childbirth
National Category
Obstetrics, Gynecology and Reproductive Medicine Anesthesiology and Intensive Care
Research subject
Family-Centred Health
Identifiers
URN: urn:nbn:se:his:diva-20877DOI: 10.1186/s12871-022-01573-0ISI: 000749527700001PubMedID: 35105307Scopus ID: 2-s2.0-85123972699OAI: oai:DiVA.org:his-20877DiVA, id: diva2:1634021
Note
CC BY 4.0
© The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:// creat iveco mmons. org/ licen ses/ by/4. 0/. The Creative Commons Public Domain Dedication waiver (http:// creat ivecommons. org/ publi cdoma in/ zero/1. 0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
Correspondence: lena.martensson@his.se School of Health Sciences, University of Skövde, P.O. Box 408, SE‑541 28 Skövde, Sweden
Open access funding provided by University of Skövde. Financial support for the study was provided by the University of Skövde, the School of Health Sciences, the research environment Digital Health Research (DHEAR) and the research group Family‑Centered Health (FamCeH).
The study was registered 08/07/2014 at ClinicalTrials.gov Identifier: NCT02213185.
2022-02-012022-02-012022-04-21Bibliographically approved