Previous research found that spirituality seems difficult to give meaning and to work with in caring. The aim of this interview study was to explore how the nursing staff experienced the spiritual dimension within caring. Data was obtained from ten nursing staff at a Swedish infection department and analyzed with content analyze. The result shows that conditions to discover and to meet spirituality depend on the staff’s ripeness, that self-knowledge affect consciousness about spirituality and in the relationship of care spirituality is visible. The meaning of spirituality is to relate to God and other people, seeking the meaning of life and attitude at fateful occasions. This study shows there is a lot of knowledge released about patients’ spiritual needs only by asking: what do you believe in? The knowledge from this study is usable booth in nursing and in educational settings.