The action of postponing an intended plan is often referred to as procrastination. Research on procrastination generally views the phenomenon as a form of self-regulation failure. Self-regulation refers to the conscious and non-conscious processes that enable individuals to guide their thoughts, feelings, and behaviors purposefully. Research indicates correlations between self-regulation and executive functions providing a fruitful integration. From a neuroscientific perspective, this integration generally associates the prefrontal cortex with top-down control whenever successful self-regulation is achieved. On the contrary, self-regulation failure appears to involve a bottom-up control, in which subcortical regions have greater influence on behavioral outcomes. Subcortical regions involved in emotional and rewarding processes, such as the amygdala and nucleus accumbens appears to lie at the coreof self-regulation failure, whereas cortical executive functions of regulating emotion and impulsive behaviors may contribute to successful self-regulation, thus overcoming procrastination. This thesis aims to obtain a deeper understanding of the mechanisms of procrastination, specifically investigating self-regulation failure and its relationship with executive functions and the neural underpinnings of self-regulation.