his.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Rare presentation of primary varicella zoster as fatal fulminant hepatitis in adult on low-dose, short-term steroid: Case report
Department of General Surgery, Hamad Medical Corporation, Doha, Qatar.
University of Skövde, School of Health and Education. University of Skövde, Health and Education. Department of Surgery, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar / College of Medicine, Qatar University, Doha, Qatar. (Individ och samhälle VIDSOC, Individual and Society)ORCID iD: 0000-0003-0961-1302
Department of General Surgery, Hamad Medical Corporation, Doha, Qatar.
Department of Internal Medicine, Hamad Medical Corporation, Doha, Qatar.
Show others and affiliations
2019 (English)In: Annals of Medicine and Surgery, ISSN 2049-0801, Vol. 48, p. 115-117Article in journal (Refereed) Published
Abstract [en]

Background: Varicella zoster virus presents clinically as primary (chickenpox) or secondary (herpes zoster) infection. Cutaneous and extracutaneous dissemination may occur, usually in immunocompromised patients. VZV hepatitis that progresses to fulminant hepatic failure is very rare and fatal. To the best of our knowledge, 9 cases have been reported to date, of which 7 were in immunocompromised adults, and only one patient was on short duration steroid therapy. Presentation of case: We present a 26-year old man who was admitted initially with acute abdomen as query persistent biliary colic. Later, he showed clinical and laboratory findings of VZV hepatitis that progressed rapidly despite maximal medical ICU support and he expired on day 3 of admission. Conclusions: Acute VZV infection may present as fulminant hepatitis. The presentation may initially be challenging for the diagnosis and should be considered if the patient has been in contact with a sick case. Low dose corticosteroid could carry a risk for fatal VZV fulminant hepatitis and should be used very cautiously especially with VZV patients’ contacts. Further causative relationships remain to be established. 

Place, publisher, year, edition, pages
Elsevier, 2019. Vol. 48, p. 115-117
Keywords [en]
Biliary colic, Case report, Fulminant acute hepatic failure, Hepatitis, Liver failure
National Category
Gastroenterology and Hepatology Infectious Medicine
Research subject
Individual and Society VIDSOC
Identifiers
URN: urn:nbn:se:his:diva-17904DOI: 10.1016/j.amsu.2019.10.034PubMedID: 31763037Scopus ID: 2-s2.0-85074811478OAI: oai:DiVA.org:his-17904DiVA, id: diva2:1372064
Available from: 2019-11-21 Created: 2019-11-21 Last updated: 2019-12-05Bibliographically approved

Open Access in DiVA

fulltext(444 kB)0 downloads
File information
File name FULLTEXT01.pdfFile size 444 kBChecksum SHA-512
0f16ed5928bd91e870a9d681cf2851839de747d4ecabc20b0e54f061b06eb367909e18c158fb45d6da7a5baa7258805f01082b75712e84fe9d36535b0383caf6
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMedScopus

Authority records BETA

El Ansari, Walid

Search in DiVA

By author/editor
El Ansari, Walid
By organisation
School of Health and EducationHealth and Education
Gastroenterology and HepatologyInfectious Medicine

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf