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The Vasopressin-Oxytocin Pathway
University of Skövde, School of Health and Education.
2018 (English)Independent thesis Basic level (degree of Bachelor), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Background: Vasopressin and Oxytocin both act as neurotransmitters and hormones. This report is a part of an original study that aimed to investigate how the endogenous release of nonapeptides was affected by caress-like touch from a beloved partner and an unfamiliar male in healthy females by analysing plasma samples collected during the touch-experiment. In this part, the same plasma samples were analysed for the release of vasopressin, with a hypothesis that the touch of an unfamiliar male would induce higher levels of vasopressin.

Method: Plasma samples were extracted and analysed with a ELISA kit provided by Enzo Life Sciences. The data from these readings were later analysed with unpaired and paired T-tests.

Results and discussion: A significant increase of vasopressin levels was detected by the partners touch among those who received the touch in the order: stranger first, partner second (p=0,0044). Which imply a contradictory increase of vasopressin to the hypothesis. The same order also produced higher oxytocin release (p=0,007), suggesting a co-release of the two nonapeptides. Without reaching significance, a weak tendency of higher vasopressin levels induced by the touch of stranger was found.  A correlational measurement indicate that oxytocin possibly can suppress the release of vasopressin.

Conclusion: The findings show that vasopressin and oxytocin share complex interactions, and that oxytocin might have a suppressive effect on vasopressin release. However, the original design of this study was focused on stimulating oxytocin release. Thus, the caress-like touch may not be enough to induce a sufficient vasopressin excretion to, further investigations designed to focus on vasopressin release is therefore of interest. 

Place, publisher, year, edition, pages
2018. , p. 17
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:his:diva-16320OAI: oai:DiVA.org:his-16320DiVA, id: diva2:1256971
Subject / course
Biomedicine/Medical Science
Educational program
Biomedicine - Study Programme
Presentation
, Skövde
Supervisors
Examiners
Available from: 2018-10-19 Created: 2018-10-18 Last updated: 2018-10-19Bibliographically approved

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CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf