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The Neurobiology of Ketamine and Addiction
University of Skövde, School of Bioscience.
2018 (English)Independent thesis Basic level (degree of Bachelor), 15 credits / 22,5 HE creditsStudent thesis
Abstract [en]

Ketamine is a dissociative anesthetic prescription drug and has been used for general anesthesia. The research surrounding this chemical compound has revealed conflicting evidence of its potential use in health care and addiction treatment. On one side, ketamine is a widespread drug of abuse associated with neurocognitive deficits and neurotoxicity, on the other side ketamine has recently been found to have a variety of potential uses, including but not limited to; antidepressant effects, reconsolidation of drug-related memories and disrupting maladaptive rumination. Ketamine’s ability to induce psychedelic and mystic experiences, reconsolidation of memories, antidepressant effects, and its ability to reduce cue-induced drug craving makes it a potentially useful tool in drug abuse therapy. Most of the negative side-effects of ketamine seem to be apparent at high doses and in frequent use but low doses and non-frequent use has a low risk of harm, therefore, careful consideration and extensive research are required before ketamine can be widely used in the public and in health care for treatment strategies. This thesis aims to explore the role of ketamine and its neurobiological effects in the treatment of addiction and depression.

Place, publisher, year, edition, pages
2018. , p. 47
Keywords [en]
ketamine, neuroscience, addiction, depression
National Category
Neurosciences
Identifiers
URN: urn:nbn:se:his:diva-15610OAI: oai:DiVA.org:his-15610DiVA, id: diva2:1219019
Subject / course
Cognitive Neuroscience
Educational program
Consciousness Studies - Philosophy and Neuropsychology
Presentation
2018-05-14, G326, Högskolevägen, Skövde, 01:56 (English)
Supervisors
Examiners
Available from: 2018-06-16 Created: 2018-06-15 Last updated: 2018-06-16Bibliographically approved

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CiteExportLink to record
Permanent link

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Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
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  • asciidoc
  • rtf