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Influence of disease features on adherence to prophylactic migraine medication
Cephalea Headache Centre, Gothenburg / Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.
Department of Public Health and Community Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID iD: 0000-0003-4616-9525
Department of Public Health and Community Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
2008 (English)In: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404, Vol. 118, no 6, p. 367-372Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: Randomized controlled trials of prophylactic treatments for migraine focus on the effects in an ideal situation and underestimate the impact of non-adherence, which in this study was examined in a natural setting.

MATERIALS AND METHODS: A sample of 174 adult migraineurs with a current prescription of pharmacological prophylaxis were consecutively recruited at a specialist clinic. Logistic regression analysis was performed to analyse the association between adherence (self-reported with the Medication Adherence Report Scale) and number of years with migraine, frequency of attacks, number of days with migraine per month, attack duration, presence of cardinal features, mean intensity of pain, and recovery between attacks.

RESULTS: One third (35%) were non-adherent. Neither demographic characteristics nor any of the disease specific variables were significantly associated with adherence.

CONCLUSION: Characteristics of the disease per se did not predict non-adherence which was also observed among patients with severe migraine. The full benefit of drugs cannot be realized at currently achieved levels of adherence.

Place, publisher, year, edition, pages
2008. Vol. 118, no 6, p. 367-372
Keywords [en]
adherence, compliance, migraine, predictors, prophylaxis
National Category
Health Sciences
Identifiers
URN: urn:nbn:se:his:diva-14630DOI: 10.1111/j.1600-0404.2008.01042.xISI: 000260821800003PubMedID: 18513346Scopus ID: 2-s2.0-51849159694OAI: oai:DiVA.org:his-14630DiVA, id: diva2:1171068
Available from: 2018-01-05 Created: 2018-01-05 Last updated: 2018-01-11Bibliographically approved

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CiteExportLink to record
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Citation style
  • apa
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  • modern-language-association-8th-edition
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  • de-DE
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  • fi-FI
  • nn-NO
  • nn-NB
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  • Other locale
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Output format
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