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Weight Loss in Patients with Dementia: Considering the Potential Impact of Pharmacotherapy
Department of Anatomy, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
Department of Anatomy, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
Department of Anatomy, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
University of Skövde, School of Health and Education. University of Skövde, Health and Education. Department of Neurology, Section for NeuroEpidemiology, State University of New York, Downstate Medical Center, USA / Neuropsychiatric Epidemiology Unit (EPINEP), Institute for Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden. (Individ och samhälle (VIDSOC), Individual and Society)
2017 (English)In: Drugs & Aging, ISSN 1170-229X, E-ISSN 1179-1969, Vol. 34, no 6, 425-436 p.Article, review/survey (Refereed) Published
Abstract [en]

Unintentional body weight loss is common in patients with dementia and is linked to cognitive impairment and poorer disease outcomes. It is proposed that some dementia medications with market approval, while aiming to improve cognitive and functional outcomes of a patient with dementia, are associated with reported body weight or body mass index loss. This review presents evidence in the published literature on body weight loss in dementia, describes selected theories behind body weight loss, evaluates the potential impact of approved dementia pharmacotherapies on body weight, considers the potential role for medical foods, understands the potential influence of treatments for neuropsychiatric symptoms and signs, and finally, summarizes this important area.

Place, publisher, year, edition, pages
2017. Vol. 34, no 6, 425-436 p.
National Category
Clinical Medicine Health Sciences
Identifiers
URN: urn:nbn:se:his:diva-13791DOI: 10.1007/s40266-017-0462-xISI: 000401319400002PubMedID: 28478593Scopus ID: 2-s2.0-85027878619OAI: oai:DiVA.org:his-13791DiVA: diva2:1112406
Available from: 2017-06-20 Created: 2017-06-20 Last updated: 2017-11-27Bibliographically approved

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Gustafson, Deborah R.

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