Tumors are mutated abnormal groups of cells that develop at any stage of life in any part of the body. Mammilla tumors appear in chest tissue that contain malignant cells in the terminal ductal-lobular unit, where the risk of the development of a mammilla tumor increases with age with a probability of 14.7%. Previous reviews have only focused on radiotherapy and digital mammography, while this review is, to the best of the author´s knowledge, the first review that encompasses the tomosynthesis and presumptive magnetic resonance using digital mammography. The aim of the meta-analysis was to determine the extent in which mass-testing of mammilla tumor metastasis can lead to its mitigation in adult females of all age-groups. The research question was the following: To what extent can mammilla tumor metastasis be mitigated by mass-testing of adult females of all age-groups? As part of the meta-analysis, a literature review was conducted using a selection of keywords in search queries on Pubmed, Libsearch and Academic Search Elite. In conclusion, mass-testing of mammilla tumor metastasis does not lead to a mitigation in adult females of all age-groups, since there was not a statistical significance of pooled value as indicated by the forest plot and the funnel plot indicated that the publication bias had some effect and the Mann-Whitney U-test also indicated that there was not a significance difference. Future research may consist of whether adult females within the age-range of 60-80 benefit from the test.