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Less syncope and milder symptoms in patients treated with pacing for induced cardioinhibitory carotid sinus syndrome: a randomized study
Högskolan i Skövde, Institutionen för vård och natur.
Cent Hosp Skövde, Dept Cardiol, Skövde, Sweden.
Sahlgrens Univ Hosp, Div Cardiol, Gothenburg, Sweden.
Univ Gothenburg, Sahlgrenska Acad, Inst Med, Gothenburg, Sweden.
2007 (engelsk)Inngår i: Europace, ISSN 1099-5129, E-ISSN 1532-2092, Vol. 9, nr 10, s. 932-936Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Aims The aim of this study was to examine the effect on symptoms in patients with induced cardioinhibitory carotid sinus syndrome (ICSS) when treated or not treated with a pacemaker.

Methods and results Sixty patients with a history of syncope or pre-syncope and ICSS were randomized to receive a permanent pacemaker (P group, n = 30) or no pacing (NP group, n = 30). ICSS was defined as a ventricular pause (i.e. asystole) lasting 3 s or more in response to carotid sinus stimulation. The patients were seen at 3 and 12 months and at symptoms. At 12 months, the rate of syncope in the NP group was 40% (n = 12) compared with 10% (n = 3) in the P group (P = 0.008). The majority (11 of 12) of the syncope recurrences in the NP group occurred during the first 3 months. Pre-syncope occurred in two patients (7%) in the NP group and in eight (27%) in the P group. Ten patients (33%) with recurrent syncope in the NP group later crossed-over to receive pacemaker implant.

Conclusions A history of syncope or pre-syncope, plus ICSS, was a strong predictor of subsequent syncope or pre-syncope. Most of the new symptoms occurred within 3 months. Pacemaker treatment effectively reduced syncope and/or resulted in milder symptoms.

sted, utgiver, år, opplag, sider
Oxford University Press, 2007. Vol. 9, nr 10, s. 932-936
Emneord [en]
Carotid sinus syndrome, Unexplained syncope, Pacemaker
HSV kategori
Forskningsprogram
Medicin
Identifikatorer
URN: urn:nbn:se:his:diva-2171DOI: 10.1093/europace/eum180ISI: 000250940600019PubMedID: 17823136Scopus ID: 2-s2.0-42449086959OAI: oai:DiVA.org:his-2171DiVA, id: diva2:32447
Tilgjengelig fra: 2008-06-09 Laget: 2008-06-09 Sist oppdatert: 2017-12-12bibliografisk kontrollert

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