Emotion Regulation refers to the process of controlling our emotions. However, the brain regions which are involved in emotional processes, such as the prefrontal cortices, are the last regions to be developed throughout the human brain. Those who are most affected by this slow development are adolescents especially since they undergo hormonal and neural changes. Previous research has shown mindfulness meditation improves emotional stability and inhibitory control. Since our brain is not fully developed until the age of 25, it is particularly interesting to get knowledge of the effect of mindfulness on emotion regulation in adolescents, which is the aim of this thesis. A total of three studies met the inclusion criteria and were included in this systematic review. The results showed a larger reaction in the amplitude of P2, N2, and late positive potentials on both negative and positive stimuli but not neutral stimuli. Differences were observed in the high vs low mindfulness adolescents in frontal EEG asymmetry during emotion regulation tasks. These findings suggest that even brief mindfulness can have a positive effect on emotion regulation processes by enhancing prefrontal cortices. These findings contribute to the understanding of whether mindfulness affects emotional regulation in a developing brain. However, future research is needed to clarify the effects of mindfulness on emotion regulation in adolescents.