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Claesson, Jan-Eric
Publications (2 of 2) Show all publications
Claesson, J.-E. (2011). Induced cardioinhibitory carotid sinus syndrome: Studies on syncope or pre-syncope and health-related quality of life in patients with or without a permanent pacemaker. (Licentiate dissertation). Institute of Medicine at Sahlgrenska Academy, University of Gothenburg
Open this publication in new window or tab >>Induced cardioinhibitory carotid sinus syndrome: Studies on syncope or pre-syncope and health-related quality of life in patients with or without a permanent pacemaker
2011 (English)Licentiate thesis, comprehensive summary (Other academic)
Place, publisher, year, edition, pages
Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, 2011. p. 22
National Category
Medical and Health Sciences
Research subject
Medical sciences
Identifiers
urn:nbn:se:his:diva-5636 (URN)978-91-633-8792-0 (ISBN)
Available from: 2012-03-27 Created: 2012-03-26 Last updated: 2017-11-27Bibliographically approved
Claesson, J.-E., Kristensson, B.-E., Edvardsson, N. & Währborg, P. (2007). Less syncope and milder symptoms in patients treated with pacing for induced cardioinhibitory carotid sinus syndrome: a randomized study. Europace, 9(10), 932-936
Open this publication in new window or tab >>Less syncope and milder symptoms in patients treated with pacing for induced cardioinhibitory carotid sinus syndrome: a randomized study
2007 (English)In: Europace, ISSN 1099-5129, E-ISSN 1532-2092, Vol. 9, no 10, p. 932-936Article in journal (Refereed) Published
Abstract [en]

Aims The aim of this study was to examine the effect on symptoms in patients with induced cardioinhibitory carotid sinus syndrome (ICSS) when treated or not treated with a pacemaker.

Methods and results Sixty patients with a history of syncope or pre-syncope and ICSS were randomized to receive a permanent pacemaker (P group, n = 30) or no pacing (NP group, n = 30). ICSS was defined as a ventricular pause (i.e. asystole) lasting 3 s or more in response to carotid sinus stimulation. The patients were seen at 3 and 12 months and at symptoms. At 12 months, the rate of syncope in the NP group was 40% (n = 12) compared with 10% (n = 3) in the P group (P = 0.008). The majority (11 of 12) of the syncope recurrences in the NP group occurred during the first 3 months. Pre-syncope occurred in two patients (7%) in the NP group and in eight (27%) in the P group. Ten patients (33%) with recurrent syncope in the NP group later crossed-over to receive pacemaker implant.

Conclusions A history of syncope or pre-syncope, plus ICSS, was a strong predictor of subsequent syncope or pre-syncope. Most of the new symptoms occurred within 3 months. Pacemaker treatment effectively reduced syncope and/or resulted in milder symptoms.

Place, publisher, year, edition, pages
Oxford University Press, 2007
Keywords
Carotid sinus syndrome, Unexplained syncope, Pacemaker
National Category
Medical and Health Sciences
Research subject
Medical sciences
Identifiers
urn:nbn:se:his:diva-2171 (URN)10.1093/europace/eum180 (DOI)000250940600019 ()17823136 (PubMedID)2-s2.0-42449086959 (Scopus ID)
Available from: 2008-06-09 Created: 2008-06-09 Last updated: 2017-12-12Bibliographically approved
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