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Saafan, T., El Ansari, W., Al-Yahri, O., Eleter, A., Eljohary, H., Alfkey, R., . . . El Osta, A. (2019). Assessment of PULP score in predicting 30-day perforated duodenal ulcer morbidity, and comparison of its performance with Boey and ASA, a retrospective study. Annals of Medicine and Surgery, 42, 23-28
Öppna denna publikation i ny flik eller fönster >>Assessment of PULP score in predicting 30-day perforated duodenal ulcer morbidity, and comparison of its performance with Boey and ASA, a retrospective study
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2019 (Engelska)Ingår i: Annals of Medicine and Surgery, ISSN 2049-0801, Vol. 42, s. 23-28Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background: /aim: Scores commonly employed to risk stratify perforated peptic ulcer patients include ASA (American Society of Anesthesiologists), Boey and peptic ulcer perforation score (PULP). However, few studies assessed and compared the accuracy indices of these three scores in predicting post PPU repair 30-day morbidity. We assessed accuracy indices of PULP, and compared them to Boey and ASA in predicting post perforated duodenal (PDU) ulcer repair 30-day morbidity. Methods: Retrospective chart review of all PDU patients (perforated duodenal ulcers only) at the largest two hospitals in Qatar (N = 152). Data included demographic, clinical, laboratory, operative, and post repair 30-day morbidity. Area under the Curve (AUC), sensitivity and specificity were computed for each of the 3 scores. Multivariate logistic regression assessed the accuracy indices of each score. Results: All patients were males (M age 37.41 years). Post PDU repair 30-day morbidity was 10.5% (16 morbidities). Older age, higher ASA (≥3), Boey (≥1) or PULP (≥8) scores, shock on admission and preoperative comorbidities; and conversely, lower hemoglobin and albumin were all positively significantly associated with higher post PDU 30-day morbidity. PULP displayed the largest AUC (72%), and was the only score to significantly predict 30-day morbidity. The current study is the first to report the sensitivity and specificity of these three scores for post PDU repair 30-day morbidity; and first to assess accuracy indices for PULP in predicting post PDU repair 30-day morbidity. Conclusion: PULP score had the largest AUC and was the only score to significantly predict post PDU repair 30-day morbidity. © 2019 The Author(s)

Ort, förlag, år, upplaga, sidor
Elsevier, 2019
Nyckelord
ASA, Boey, Perforated duodenal ulcer, Perforated peptic ulcer, Perforated peptic ulcer score, PULP
Nationell ämneskategori
Kirurgi
Forskningsämne
Individ och samhälle VIDSOC
Identifikatorer
urn:nbn:se:his:diva-16939 (URN)10.1016/j.amsu.2019.05.001 (DOI)000468373600006 ()2-s2.0-85065728629 (Scopus ID)
Tillgänglig från: 2019-06-03 Skapad: 2019-06-03 Senast uppdaterad: 2019-06-11Bibliografiskt granskad
El Ansari, W. & Berg-Beckhoff, G. (2019). Association of health status and health behaviors with weight satisfaction vs. Body image concern: Analysis of 5888 undergraduates in Egypt, Palestine, and Finland. Nutrients, 11(12), Article ID 2860.
Öppna denna publikation i ny flik eller fönster >>Association of health status and health behaviors with weight satisfaction vs. Body image concern: Analysis of 5888 undergraduates in Egypt, Palestine, and Finland
2019 (Engelska)Ingår i: Nutrients, ISSN 2072-6643, E-ISSN 2072-6643, Vol. 11, nr 12, artikel-id 2860Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Little is known about the relationships between weight satisfaction, body image concern, healthy nutrition, health awareness, and physical activity among college students across culturally different countries. We assessed country and sex-specific associations between health status (self-rated health, depression, BMI), healthy behavior (healthy nutrition, physical activity, health awareness), weight satisfaction, and body image concern via a cross-sectional survey (5888 undergraduates) in Egypt, Palestine, and Finland. This health and wellbeing survey employed identical self-administered paper questionnaires administered at several Universities in two Eastern Mediterranean countries (Egypt, Palestine—Gaza Strip), and an online-survey comprising the same questions in Finland. Regression analyses were employed. Health status variables exhibited the strongest associations; high BMI and more depressive symptoms were more often among students satisfied with their weight (except in Palestine), but they were positively associated with body image concern irrespective of country or gender. Self-rated health was not associated with body image concern or weight satisfaction. Healthy behaviors were not associated with body image concern or weight satisfaction. Depressive symptoms and BMI were the most prominent predictors for body image concern. There were country-specific consistent results when using the body image concern score. Further research is necessary to compare body image across different cultures and countries. 

Ort, förlag, år, upplaga, sidor
MDPI, 2019
Nyckelord
body image, college students, depressive symptoms, health awareness, health behaviors, healthy nutrition, physical activity, weight satisfaction, adolescent, adult, article, awareness, Beck Depression Inventory, body mass, body weight management, body weight satisfaction, cross-sectional study, depression, female, health behavior, health status, human, income, Likert scale, major clinical study, male, nutrition, obesity, physical well-being, practice guideline, questionnaire, self rated general health, social stratification, university student
Nationell ämneskategori
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi Näringslära
Forskningsämne
Individ och samhälle VIDSOC
Identifikatorer
urn:nbn:se:his:diva-17991 (URN)10.3390/nu11122860 (DOI)31766557 (PubMedID)2-s2.0-85075404215 (Scopus ID)
Tillgänglig från: 2019-12-11 Skapad: 2019-12-11 Senast uppdaterad: 2019-12-17Bibliografiskt granskad
Saafan, T., El Ansari, W. & Bashah, M. (2019). Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?. Obesity Surgery, 29(7), 2166-2173
Öppna denna publikation i ny flik eller fönster >>Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?
2019 (Engelska)Ingår i: Obesity Surgery, ISSN 0960-8923, E-ISSN 1708-0428, Vol. 29, nr 7, s. 2166-2173Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background Obesity is a risk for many different cancers. Laparoscopic sleeve gastrectomy (LSG) is common, and benign or pre-malignant histopathology types are reported in the removed gastric specimens. We assessed whether higher BMI was associated with certain benign or pre-malignant histopathological changes. Method Retrospective chart review of all primary LSG patients (N = 1555). Demographic, clinical, and LSG histopathology data were retrieved. BMI of patients with specific benign or pre-malignant conditions in their gastric specimens was compared with the BMI of the rest of the patients with abnormal histopathology specimens and also compared with the BMI of patients with normal control specimens. Results Females comprised 70% of the patients. Mean BMI were 46.3 (females) and 48 (males). Normal LSG specimens comprised 52%. Most common abnormal histopathologies were chronic inactive gastritis (33%), chronic active gastritis (6.8%), follicular gastritis (2.7%), lymphoid aggregates (2.2%), intestinal metaplasia (1.4%) and GIST (0.7%). After controlling for confounders (age, gender, H. pylori, diabetes mellitus type 2, hypertension), no significant association was observed between the BMI of patients with specific benign or pre-malignant histopathology compared with the BMI of the rest of the patients with abnormal histopathologies and compared to the BMI of patients with normal histopathologies. Conclusion When confounders were taken into account, there appeared no significant associations between the BMI of patients with specific benign or pre-malignant histopathology compared with the BMI of the rest of the patients with abnormal histopathologies and compared to the BMI of patients with normal histopathologies of their gastric specimens. There was a very weak correlation between BMI and other covariates.

Ort, förlag, år, upplaga, sidor
USA: Springer, 2019
Nyckelord
Laparoscopic sleeve gastrectomy, LSG, Histopathologies, BMI, Pre-malignant histopathology, Benign histopathology
Nationell ämneskategori
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
Forskningsämne
Individ och samhälle VIDSOC
Identifikatorer
urn:nbn:se:his:diva-17222 (URN)10.1007/s11695-019-03801-y (DOI)000469767700021 ()30989568 (PubMedID)2-s2.0-85064708438 (Scopus ID)
Tillgänglig från: 2019-06-20 Skapad: 2019-06-20 Senast uppdaterad: 2019-08-06Bibliografiskt granskad
Elbardisi, H., El Ansari, W., Majzoub, A. & Arafa, M. (2019). Does varicocelectomy improve semen in men with azoospermia and clinically palpable varicocele?. Andrologia, Article ID e13486.
Öppna denna publikation i ny flik eller fönster >>Does varicocelectomy improve semen in men with azoospermia and clinically palpable varicocele?
2019 (Engelska)Ingår i: Andrologia, ISSN 0303-4569, E-ISSN 1439-0272, artikel-id e13486Artikel i tidskrift (Refereegranskat) Epub ahead of print
Abstract [en]

The effectiveness of varicocelectomy in nonobstructive azoospermia is controversial. The current study assessed the efficacy of microsurgical subinguinal varicocelectomy in nonobstructive azoospermic men with palpable varicocele and to evaluate predictive parameters of outcome. We reviewed the records of 723 patients who had microsurgical varicocelectomy and diagnostic testicular biopsy between 2012 and 2016 at a tertiary medical centre. Data pertaining to the physical, laboratory (semen analysis and hormonal profile) and histopathology features were examined, exploring the predictors of improvement in semen analysis post-varicocelectomy. In total, 42 patients with mean age 35.71 +/- 6.35 years were included. After a mean varicocelectomy follow-up of 6.7 months, motile spermatozoa in the ejaculate could be observed in 11 patients (26.2). Out of all the factors examined, only testicular histopathology significantly predicted post-varicocelectomy outcome, where 8/11 patients exhibited hypospermatogenesis, and 3/11 Sertoli cell-only regained spermatozoa in semen. Microsurgical varicocelectomy in nonobstructive azoospermic men with clinically palpable varicocele can result in sperm appearance in the ejaculate with the highest success expected in hypospermatogenesis.

Ort, förlag, år, upplaga, sidor
Wiley-Blackwell, 2019
Nyckelord
nonobstructive azoospermia, spermatozoa, varicocele, varicocelectomy
Nationell ämneskategori
Reproduktionsmedicin och gynekologi
Forskningsämne
Individ och samhälle VIDSOC
Identifikatorer
urn:nbn:se:his:diva-18034 (URN)10.1111/and.13486 (DOI)000501904700001 ()31825116 (PubMedID)2-s2.0-85076342227 (Scopus ID)
Tillgänglig från: 2019-12-27 Skapad: 2019-12-27 Senast uppdaterad: 2020-01-08Bibliografiskt granskad
Hammad, Y., Elmoghazy, W., El Ansari, W., Lance, M., Zaghw, A. & Shallik, N. (2019). Experimental effect of different dilutions of blood with human plasma protein fraction and large dose factor one on blood coagulation and chemistry in vitro. Indian Journal of Anaesthesia, 63(12), 1015-1021
Öppna denna publikation i ny flik eller fönster >>Experimental effect of different dilutions of blood with human plasma protein fraction and large dose factor one on blood coagulation and chemistry in vitro
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2019 (Engelska)Ingår i: Indian Journal of Anaesthesia, ISSN 0019-5049, Vol. 63, nr 12, s. 1015-1021Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background and Aims: Human plasma protein fraction 5% (PPF5%) is an albumin-based colloid used to expand the plasma volume during volume deficiency. The current basic medical experimental study assessed in vitro coagulation of PPF5% solution and its effects on blood coagulation and chemistry. Methods: The study involved 20 volunteers, and each volunteer donated 20-50 ml of fresh blood. Three dilutions of blood with PPF5% dilutions were prepared (30, 50, and 70%). The fibrinogen dose required to correct coagulation in the 50% diluted samples was assessed (two doses used). The thromboelastogram (TEG) measured the haemostatic parameters (fibrinogen level, initiation of coagulation [R time], kinetics [K], acceleration of coagulation [α angle], maximum amplitude [MA] and coagulation index [CI]), and the ABL gas analyser measured the blood chemistry changes. Results: All dilutions showed significant TEG and blood chemistry changes when compared to controls. The two doses of fibrinogen corrected the clot formation speed with no significant difference in speed between the two doses. Acidosis measured by the strong ion gap (SID) and pH were significant for all dilutions when compared with the baseline. The 30% dilution remained within the lower normal acceptable value while 50% dilution was beyond the critical normal values. Conclusion: In vitro PPF5% to replace blood loss up to 50% dilution did not have significant coagulation and blood chemistry effects while coagulopathy should be expected in extreme dilutions (70%). Fibrinogen in a dose equivalent to 4 gm/70 kg adult improved clot strength at 50% dilution. 

Ort, förlag, år, upplaga, sidor
Wolters Kluwer, 2019
Nyckelord
Blood coagulation and chemistry, fibrinogen level, human plasma protein fraction, thromboelastography
Nationell ämneskategori
Anestesi och intensivvård Kardiologi
Forskningsämne
Individ och samhälle VIDSOC
Identifikatorer
urn:nbn:se:his:diva-18056 (URN)10.4103/ija.IJA_398_19 (DOI)31879426 (PubMedID)2-s2.0-85076812297 (Scopus ID)
Anmärkning

Wolters Kluwer Medknow Publications

Tillgänglig från: 2020-01-02 Skapad: 2020-01-02 Senast uppdaterad: 2020-01-10Bibliografiskt granskad
Toffaha, A., El Ansari, W., Elaiwy, O., Obaid, M., Al-Yahri, O. & Abdelazim, S. (2019). First sliding Amyand hernia harbouring appendicular schistosomiasis: Case report. International journal of surgery case reports, 63, 143-146
Öppna denna publikation i ny flik eller fönster >>First sliding Amyand hernia harbouring appendicular schistosomiasis: Case report
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2019 (Engelska)Ingår i: International journal of surgery case reports, ISSN 2210-2612, E-ISSN 2210-2612, Vol. 63, s. 143-146Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Introduction: Amyand's hernia (AH) is rare, schistosomiasis of the appendix is very uncommon, and both conditions coexisting together is an extremely rare event. Pre-operative diagnosis of each of the two conditions is usually difficult. To the best of our knowledge, the current paper is first to report both these two conditions in coexistence. Presentation of case: A 31-year old man who had no comorbidities was admitted electively as a day case of non-complicated right indirect inguinal hernia. Further history and physical examination were unremarkable. Intraoperatively the patient was found to have right sliding AH with appendicular schistosomiasis (AS). The patient underwent Lichtenstein repair of the hernia with appendectomy. On follow up he was referred to infectious disease clinic, and the post-operative course was uneventful. Conclusions: Intraoperative identification of non-typical hernia sac before its opening should alert the surgeon to the possibility of sliding hernia and the presence of an organ as a part of the sac. Rare causes of appendicular masses like schistosomiasis granuloma should be considered in endemic areas or immigrants from these areas, despite the difficulty of preoperative diagnosis. Management should follow general guidelines of appendectomy, hernia repair and dealing with the associated pathology if present. 

Ort, förlag, år, upplaga, sidor
Elsevier, 2019
Nyckelord
Case report, Inguinal hernia, Intestinal schistosomiasis, Tropical disease
Nationell ämneskategori
Kirurgi Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi Gastroenterologi
Forskningsämne
Individ och samhälle VIDSOC
Identifikatorer
urn:nbn:se:his:diva-17781 (URN)10.1016/j.ijscr.2019.09.014 (DOI)000493909500033 ()31585325 (PubMedID)2-s2.0-85072758444 (Scopus ID)
Tillgänglig från: 2019-10-10 Skapad: 2019-10-10 Senast uppdaterad: 2019-12-19Bibliografiskt granskad
Sulieman, I., Elmoghazy, W., El Ansari, W., Elaffandi, A. & Khalaf, H. (2019). Gallbladder cancer: 7-Year experience from Qatar. Annals of Medicine and Surgery, 44, 33-38
Öppna denna publikation i ny flik eller fönster >>Gallbladder cancer: 7-Year experience from Qatar
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2019 (Engelska)Ingår i: Annals of Medicine and Surgery, ISSN 2049-0801, Vol. 44, s. 33-38Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background: Gallbladder cancer (GC) is a relatively rare disease. To date, there are no studies describing the epidemiology of this disease in Qatar. Objective: To study the epidemiology of Gallbladder Cancer in Qatar. Methods: A retrospective analysis of the cases of GC in Hamad General Hospital in Qatar from 2009 to 2016. Results: Thirty-five patients presented with GC during the study period, 10 females (28.6%) and 25 males (71.4%). Fourteen patients (40%) were diagnosed incidentally after laparoscopic cholecystectomy, 16 (48.6%) were diagnosed pathologically, and 4 (11.4%) were diagnosed radiologically. The median age at diagnosis was 54 years (31–78). 74.3% of the disease occurred in patients less than 60 years old. Metastatic disease was discovered in 25 patients (71.4%) versus no metastasis in 10 patients (28.6%). The most common sites for metastasis were the liver (42.9%), peritoneum (25.7%), and lymph nodes (25.7%). Curative central hepatic resection was done in 8 patients (22.9%). Pathology showed adenocarcinoma in 27 patients (77.1%), neuroendocrine tumor in 3 patients (8.6%) and high-grade dysplasia in 1 patient (2.9%). No histopathology was available for 4 patients (11.4%). Twenty-eight patients (80.0%) had regular follow up, with 22 (62.9%) still alive. Six patients (17.1%) died during follow up with survival after diagnosis ranging from 42 days to 6.8 years. Conclusions: In Qatar, due to the unique demographics, GC is more common in males and younger age groups. Most of the patients present late with metastasis, but curative resection is associated with long-term survival.

Ort, förlag, år, upplaga, sidor
Elsevier, 2019
Nyckelord
Epidemiology, Gallbladder cancer, Qatar, Risk factors, Survival
Nationell ämneskategori
Klinisk medicin
Forskningsämne
Individ och samhälle VIDSOC
Identifikatorer
urn:nbn:se:his:diva-17418 (URN)10.1016/j.amsu.2019.06.001 (DOI)000477739600007 ()2-s2.0-85067824950 (Scopus ID)
Tillgänglig från: 2019-07-09 Skapad: 2019-07-09 Senast uppdaterad: 2019-11-11Bibliografiskt granskad
Elmoghazy, W., Ahmed, K., Vijay, A., Kamel, Y., Elaffandi, A., El Ansari, W., . . . Khalaf, H. (2019). Hepatocellular carcinoma in a rapidly growing community: Epidemiology, clinico-pathology and predictors of extrahepatic metastasis. Arab Journal of Gastroenterology, 20(1), 38-43
Öppna denna publikation i ny flik eller fönster >>Hepatocellular carcinoma in a rapidly growing community: Epidemiology, clinico-pathology and predictors of extrahepatic metastasis
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2019 (Engelska)Ingår i: Arab Journal of Gastroenterology, ISSN 1687-1979, Vol. 20, nr 1, s. 38-43Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background and study aims: Hepatocellular carcinoma (HCC) with extrahepatic metastasis has been studied, however, data from the Middle East remain scarce. In this study, we assess epidemiology of HCC in Qatar, and identify predictors of the metastatic behaviour. Patients and methods: All newly-diagnosed HCC patients on top of liver cirrhosis between 2011 and 2015 were included in the study. Results: A total of 180 patients met our inclusion criteria. The mean age was 58.8 ± 10.5 years with a mean follow-up of 1.0 ± 1.1 years. There were 150 male patients and HCV was the most common cause of liver cirrhosis 108 (60%), and 22 (12.2%) patients were classified as Child-Pugh class C. The overall survival of 51.1%, and 47 (26%) had at least one extrahepatic metastasis at the time of diagnosis. Single site metastasis was diagnosed in 10 patients, whereas 37 patients had multiple sites metastases. We compared patients who had metastases with patients who did not have metastasis at the time of diagnosis of HCC regarding several variables, and analysis revealed that tumour diameter larger than 5 cm (OR = 6.10, 95% CI = 1.85–20.12) (p = 0.003), and bilobar liver involvement (OR = 5.49, 95% CI = 1.10–27.30) (p = 0.037) were independent predictors of metastatic behaviour of HCC. Conclusion: The incidence of HCC is rising in our population, extrahepatic metastasis is no longer rare and tumours larger than 5 cm and bilobar involvement are determinants of the extrahepatic metastasis. © 2019 Pan-Arab Association of Gastroenterology

Ort, förlag, år, upplaga, sidor
Elsevier, 2019
Nyckelord
Hepatocellular carcinoma, Incidence, Maximal tumour diameter, Metastasis, Prognosis, Risk factors, Total tumour volume
Nationell ämneskategori
Gastroenterologi
Forskningsämne
Individ och samhälle VIDSOC
Identifikatorer
urn:nbn:se:his:diva-16705 (URN)10.1016/j.ajg.2019.01.006 (DOI)000463364700008 ()30853257 (PubMedID)2-s2.0-85062444660 (Scopus ID)
Tillgänglig från: 2019-03-18 Skapad: 2019-03-18 Senast uppdaterad: 2019-04-30Bibliografiskt granskad
Elhag, W., El Ansari, W., Razaq, S., Elsherif, M. & Mustafa, I. (2019). Lorcaserin vs. Phentermine among non-surgical and surgical obese patients: Anthropometric, glycemic, lipid, safety and cost outcomes. Annals of Medicine and Surgery, 45, 75-81
Öppna denna publikation i ny flik eller fönster >>Lorcaserin vs. Phentermine among non-surgical and surgical obese patients: Anthropometric, glycemic, lipid, safety and cost outcomes
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2019 (Engelska)Ingår i: Annals of Medicine and Surgery, ISSN 2049-0801, Vol. 45, s. 75-81Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background: To evaluate effectiveness, safety, and costs of Lorcaserin vs. phentermine among obese non–surgical and surgical patients (post bariatric surgery). Methods: This retrospective study retrieved charts of all patients (January 2013–June 2016) who received Lorcaserin or phentermine for 3 months. The study assessed anthropometric, glycemic, and lipid changes, as well as side effects and cost of medications among overweight and obese non-surgical (n = 83) and surgical patients (n = 46). These two patient groups were compared using Chi-square (χ2) and unpaired‘t’ test for qualitative and quantitative variables respectively. Results: At 3 months, among the non-surgical group, Phentermine patients had greater percentage of total weight loss (TWL%) (7.65 ± 8.26 vs. 2.99 ± 3.72%, P = 0.003), and greater BMI reduction (−3.16 ± 3.63 vs. −1.15 ± 1.53 kg/m2, P = 0.003) than Lorcaserin. Within the surgical group, Lorcaserin patients had significantly smaller TWL% (1.86 ± 5.06 vs. 7.62 ± 9.80%, P = 0.012), and smaller BMI reduction (−0.74 ± 1.80 vs. −3.06 ± 4.08 kg/m2, P = 0.012) than Phentermine. Lorcaserin exhibited significant total cholesterol and LDL improvements only among surgical patients with significant weight reduction (≥5% TW). Both medications were not associated with glycemic improvements among non-surgical and surgical groups. Phentermine had slightly more side effects but was less expensive. Conclusions: Among both patient groups, phentermine was more effective in achieving weight loss. Lorcaserin showed dyslipidemia improvements only among surgical patients who achieved significant weight reduction. Anti-obesity medications as part of weight management programs can result in weight loss among non-surgical and surgical patients, or halt weight regain among surgical patients. This is the first study to evaluate the effectiveness and safety of two anti-obesity medications (lorcaserin vs. phentermine) among two distinct obese patient groups, non-surgical and surgical patients. 

Ort, förlag, år, upplaga, sidor
Elsevier, 2019
Nyckelord
Obesity, Lorcaserin, Phentermine, Weight regain, Bariatric surgery, Lipid profile, Glycemic, parameters
Nationell ämneskategori
Kirurgi
Forskningsämne
Individ och samhälle VIDSOC
Identifikatorer
urn:nbn:se:his:diva-17505 (URN)10.1016/j.amsu.2019.07.024 (DOI)000482224200016 ()31388419 (PubMedID)2-s2.0-85069915724 (Scopus ID)
Tillgänglig från: 2019-08-09 Skapad: 2019-08-09 Senast uppdaterad: 2019-11-18Bibliografiskt granskad
Abdulrazzaq, S., Elhag, W., El Ansari, W., Mohammad, A. S., Sargsyan, D. & Bashah, M. (2019). Primary vs Revisional Gastric Bypass for Weight Loss and Improvements in Comorbidities: Comparisons at Mid-term Follow-up. Obesity Surgery
Öppna denna publikation i ny flik eller fönster >>Primary vs Revisional Gastric Bypass for Weight Loss and Improvements in Comorbidities: Comparisons at Mid-term Follow-up
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2019 (Engelska)Ingår i: Obesity Surgery, ISSN 0960-8923, E-ISSN 1708-0428Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background: Revisional gastric bypass (R-RYGB) surgery is utilized for the management of inadequate weight loss or weight regain observed after some cases of bariatric surgeries. Data on the mid-term effectiveness of primary gastric bypass (P-RYGB) compared to R-RYGB (e.g., post sleeve gastrectomy or gastric banding) are controversial. Methods: Retrospective chart review of all patients who received P-RYGB and R-RYGB (January 2011 - June 2015) at our center. One hundred and twenty patients who underwent P-RYGB and 34 R-RYGB who completed 18 months follow-up were included. We compared the effectiveness of P-RYGB with R-RYGB by assessing four anthropometric, two glycemic, and four lipid parameters, as well as the control of type 2 diabetes (T2DM), hypertension and dyslipidemia in terms of remission, improvement, persistence, relapse and de novo. The current study also assessed mortality and complications rates. Results: There were no significant differences in the baseline characteristics of patients who received P-RYGB with those who received R-RYGB in terms of age, gender and preoperative BMI. However, at 18 months: a) Patients who received P-RYGB had lower mean weight (P = 0.001) and BMI (P <0.001), reflected by a higher mean delta BMI (P = 0.02), TWL%(P <0.0001) and EWL%(P < 0.0001); b) No differences were observed between the two patients groups in terms of glycemic parameters, lipid profiles, and control of T2DM, hypertension, and dyslipidemia; and, c) No deaths were reported among both patients groups, and complication rates were comparable. Conclusion: Although R-RYGB effectively addressed inadequate weight loss, weight regain and recurrence of comorbidities after restrictive bariatric surgery, R-RYGB resulted in inferior weight loss compared to P-RYGB. There were no significant differences between the two procedures in terms of their clinical control of T2DM, hypertension and dyslipidemia. Both procedures exhibited comparable complication rates. 

Ort, förlag, år, upplaga, sidor
Springer, 2019
Nyckelord
Dyslipidemia, Hypertension, Primary gastric bypass, Revisional Gastric bypass, Type 2 diabetes, Weight loss outcome
Identifikatorer
urn:nbn:se:his:diva-18125 (URN)10.1007/s11695-019-04280-x (DOI)31865551 (PubMedID)2-s2.0-85077172688 (Scopus ID)
Tillgänglig från: 2020-01-10 Skapad: 2020-01-10 Senast uppdaterad: 2020-01-14
Organisationer
Identifikatorer
ORCID-id: ORCID iD iconorcid.org/0000-0003-0961-1302

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