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  • Lennermo, Linnéa
    University of Skövde, School of Bioscience.
    Att drabbas av stroke: En litteraturstudie baserad på självbiografier2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: Stroke includes bleeding or plugs in one or more blood vessels in the brain and is a disease that affects many people around the world every day. Having a stroke can cause both physical and mental disabilities and can thus have major consequences for the affected individual. Increased knowledge about experiences of having a stroke can help nurses to give good and specific care, which can be crucial for the patient’s health and wellbeing. Aim: To describe experiences of having a stroke. Method: A literature study where six autobiographies were analyzed through a qualitative content analysis. Result: Four main categories emerged from the analysis: A changed lifeworld, To end up in the hands of others,To fluctuate between hope and despair and Others’ impact on the patient’s well-being. Conclusion: Having a stroke may result in both physical and mental changes and may have major consequences for the patient’s health and well-being. The result of this study may contribute knowledge and understanding about how stroke may affect a person, which may help healthcare staff to improve the care of these patients and to ease suffering.

  • Muhrblom, Sanna
    University of Skövde, School of Health Sciences.
    Sjuksköterskor på insats: Sjuksköterskors erfarenheter av att arbeta under strid: En litteraturöversikt2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: There are at least 32 armed conflicts in the world right now and through the UN and NATO there are military deployments ongoing. Nurses have been part of the armed forces' work throughout history and are today always a part of the Armed Forces. Nurses receive training in combat medical care based on analyses of deaths and injuries from combat. A large proportion of those who come home after being on deployments suffer from mental health problems, such as PTSD. Aim: Describe nurses' experiences of working incombat-related situations within the armed forces. Method: A literature review with qualitative and quantitative articles. Result: The analysis identified three main categories: Preparing for combat, In the heat of the combat, Recover after combat and seven subcategories. Conclusion: The result shows that nurses before mission, during mission and after mission experience mental and physical impact. Nurses feel that they have adequate training in health care to go on the mission, but when it comes to military training and culture, preparatory training lacks. It’s a fact that once the nurses are on their duty to work, they experience not being prepared for their role in the battle, combat situations, injuries andillnesses they need to deal with.

  • Pour Akaber, Shirin
    University of Skövde, School of Bioscience.
    Identification of DEGs in B cells of patients with common variable immunodeficiency and healthy donors2019Independent thesis Advanced level (degree of Master (Two Years)), 30 credits / 45 HE creditsStudent thesis
    Abstract [en]

    Common variable immunodeficiency (CVID) is a rare primary immune deficiency (1:25000) in which patients have a reduction in antibody production and very low titres in one or more of their Ig isotypes, (IgG, IgA and sometimes IgM). This disease can cause different symptoms such as: bronchiectasis, chronic lung disease and even autoimmunity, polyclonal lymphocytic infiltration, lymphoma and death. The underlying causes of CVID are still largely unknown but studies show that different factors like primary B-cell dysfunctions, defects in T cells and antigen-presenting cells are involved. Quantitative analysis of gene expression is of high importance in understanding the molecular mechanisms underlying this diseases´ genome regulation. Next-generation RNA-seq has enabled researchers to analyse both coding and non-coding regions of RNA, and therefore has made it possible to identify differentially expressed genes in large-scale data, especially in polygenic diseases like CVID. The aim for this study was to identify the differentially expressed genes between CVID patients and healthy donors to identify important genes and molecular mechanisms underlying this diseases´ genome regulation. For this matter, whole genome RNA-seq analysis was performed on RNA isolated from sorted peripheral blood naïve and CD27bright memory B cells from healthy donors (n=7) and CVID patients (n=5). The RNA-seq data for the samples was collected and undergone several bioinformatical and analytical steps to be processed. After quality control and trimming, the data files were assembled to the human genome. Then, the transcriptomic data of the CVID patients was compared with the healthy donors to identify differentially expressed genes (DEGs). From this study, it was found that PAX5, ETS1, POU2AF1, SPIB, BACH 2, EBF1 and PRDM1 play an important role on regulation of the B cells and especially this disease. Also, the Ikaros family, toll-like receptors and a number of chemokine and cytokine receptors were found out to have high importance regarding CVID.

  • Sreenivasulu, Ajay
    University of Skövde, School of Informatics.
    Evaluation of cluster based Anomaly detection2019Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Anomaly detection has been widely researched and used in various application domains such as network intrusion, military, and finance, etc. Anomalies can be defined as an unusual behavior that differs from the expected normal behavior. This thesis focuses on evaluating the performance of different clustering algorithms namely k-Means, DBSCAN, and OPTICS as an anomaly detector. The data is generated using the MixSim package available in R. The algorithms were tested on different cluster overlap and dimensions. Evaluation metrics such as Recall, precision, and F1 Score were used to analyze the performance of clustering algorithms. The results show that DBSCAN performed better than other algorithms when provided low dimensional data with different cluster overlap settings but it did not perform well when provided high dimensional data with different cluster overlap. For high dimensional data k-means performed better compared to DBSCAN and OPTICS with different cluster overlaps

  • Landén, Rebecca
    University of Skövde, School of Health Sciences.
    Patienters upplevelser av att leva med hjärtsvikt: En litteraturöversikt2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: In Sweden, approximately two percent of the population lives with heart failure. Heart failure in an in incurable disease that has a bad prognosis and compared to cancer. Purpose: To elucidate and compile research that describes patients’ experiences of living with heart failure. Method: This study is a Literature Review that focuses on studies that have been scientifically reviewed. Results: Two themes were found that were limited lives and changed lives. Nine sub-themes created were, to never be rested, to feel suffocated, to not dare fall asleep, living in prison, changed lifestyle, uncertain the future, the joy that disappears, to give control to someone else and to move on with life. Conclusion: Heart failure limits patient’ lives to the physical limitations that are mainly due to dyspné and fatigue. Heart failure changes patients by changing their lifestyle and being emotionally affected which leads to reduced quality of life. With this knowledge, nurses can gain an increased understanding of what it is to live with heart failure, thereby being able to provide more person-centered care.

  • Sundberg, Anna
    University of Skövde, School of Health Sciences.
    Hemodialys ur patienters perspektiv: Erfarenheter från vardagen - en litteraturbaserad studie2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: Haemodialysis can replace the filtration function of the kidneys when needed at end-stage renal disease. It is a treatment that causes suffering of different types and consumes a lot of time and has a physical and psychological effect. Knowledge, information, autonomy and participation are of importance for patients perceptions of wellbeing and the nurse has a supporting role. Aim: To describe patient’s experiences of their daily life when on haemodialysis. Method: Literature based with analysis of qualitative studies. Result: From the analysis two main categories emerged; Haemodialysis control daily life and Adapting to a different life, with seven subcategories. Conclusion: Restrictions in daily life was difficult to manage and the patients needed knowledge to be able to go through the day. The behaviour of the nurse had an influence on the patient, both positive and negative. Every patient experience their daily live different when on haemodialysis and some manage well and felt healthy while some suffered and felt illness and had no motivation.

  • Wong, Tsz San
    University of Skövde, School of Health Sciences.
    Ett långsamt farväl tillsammans med ALS: En analys av självbiografier.2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: Amyotrophic lateral sclerosis (ALS) is a motor neuron disease caused by gradual deterioration and death of motor neurons, resulting in loss of function in the associated muscles due to the lack of nerve signals. People with ALS are a vulnerable group with physically limited ability to express themselves. Aim: The aim of this study was to identify and follow experiences of living with ALS, by examining narratives of ALS affected persons. Method: The study is based on a qualitative approach with a content analysis of autobiographies written by people with ALS. Results: The disease causes multidimensional dilemmas of existential kinds that contribute to suffering and that family is an important part that affects the perception of the disease. The primary causes of suffering are found to be the fear of affected personal dignity and alienation. Conclusion: The nurse has a central function in the care of ALS-affected persons. The nurse must strive to establish a good relationship with the caretaker and their relatives, thus striving to maximize the support from a holistic perspective, which increases the possibility for the caretaker to experience well-being.

  • Solaka, Linda
    et al.
    University of Skövde, School of Health Sciences.
    Aljajeh, Nebal
    University of Skövde, School of Health Sciences.
    När livet stannar upp: Att vara anhörig till en person som diagnostiserats med Alzheimers sjukdom2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: When a person is diagnosed with AS, a drastic change takes place in both the patient's and the relatives' lives. The relatives become an informal caregiver, they enter into a foreign world of suffering. In order to alleviate this suffering, the nurse must have greater knowledge and a better understanding of how the relatives experience their changed lifeworld. Aim: The aim of this study is to explore how relatives experience taking care of a partner with AS portrayed in films. Methods: An empirical qualitative approach with direct and unstructured observations of three films has been used. The material consisted of field notes which were analyzed with the help of a qualitative content analysis. Results: Relatives' experiences of caring for a partner with AS are presented in four themes: when the lifeworld texture ruptures; sorrow; loss of freedom; letting go. Conclusion: Relatives feel a responsibility to care for their partner. Becoming an informal caregiver means a loss of freedom, social isolation and a feeling of loneliness. The emotional experiences are the main cause of the suffering. The films used in this study are a powerful medium that can be used for educational purposes.

  • Ström, Fanny
    et al.
    University of Skövde, School of Health Sciences.
    Sarajärvi, Hannah
    University of Skövde, School of Health Sciences.
    När livet är begränsat: Att leva med obotlig cancer2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: Cancer is the leading cause of death for individuals under 80 in the world. In 2018 about 40 million individuals were in need of palliative care, therefore it`s important that nurses have knowledge of what good palliative care means. Cancer has both physical and mental impact on individuals’ lives, which can cause suffering. Aim: The aim of the study is to describe younger adults’ experiences of living and being cared for with terminal cancer. Method: The method was a qualitative content analysis in which data collection was done through four narrative stories in autobiographies. Results: The results were presented in four themes and eleven sub-themes. People in the surroundings were of great importance to the individuals as they provided support. The illness led to physical impact through side effects, symptoms and a changed self-image, while psychological impact could include strong emotional impact and existential thoughts. Conclusion: Life was turned upside down by the cancer diagnosis and the individuals hadto start identifying themselves with the disease. Cancer contributed to suffering but through acceptance, well-being despite disease could be achieved. It was important for caregivers to respond to unique thoughts and needs to create opportunities for a good relationship.

  • Hjelm Wallgren, Julia
    et al.
    University of Skövde, School of Health Sciences.
    Odhner Källgård, Martina
    University of Skövde, School of Health Sciences.
    Våld i nära relationer: Ett ämne som väcker känslor - En litteraturöversikt2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: Intimate partner violence (IPV) is a growing health problem and in a global perspective, 35% of all women has been exposed to some kind of violence in a relationship in their lifetime. 67% of the violent crimes with a deadly outcome in Sweden where caused by a male partner or an ex. male partner. This corresponds to 22 deaths. When women seek care, they witness nurses not having enough knowledge about the subject, which leads to deficiency in the healthcare. Purpose: The purpose was to illuminate nurses experiences of meeting women, who has been subjects to violence in close relationships. Method: A literary overview according to the Friberg method was performed. The data collection consisted of 10 scientific articles that illuminated nurses experiences with patients who have been exposed to IPV. The articles where then thoroughly reviewed and analysed and further encapsulated in to topics and subtopics. Result: The literary overview resulted in five topics and 16 subtopics. The following part shows the titles of the topics: It is not just to ask, To handle a positive response, The value of establishing good relationships, To doubt your profession and The value of good cooperations. Conclusion: To take care of exposed women is, according to nurses, very complex. There are several circumstances affecting the encounters with these women. This complex subject prevents nurses to perform at their best in their profession, which in turn leads to unnecessary suffering for women who has been subjects to IPV.

  • Seger, Martina
    et al.
    University of Skövde, School of Health Sciences.
    Andersson, Therese
    University of Skövde, School of Health Sciences.
    Kvinnors upplevelse av att drabbas av en hjärtinfarkt2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: Women's symptoms of myocardial infarction differ from the general symptomatology, which may be diffuse pain, fatigue and anxiety. After myocardial infarction, the body and lifestyle are perceived changed, physical and mental limitations create suffering. Well-being can be achieved even during the presence of illness, however, control over the life situation is required. The nurse should possess knowledge to relieve suffering and promote health and well-being. Purpose: To shed light on women's experiences of being affected by a heart attack. Method: A qualitative literature review where the data material consists of ten scientific articles based on the perspective of the patient. Results: In the result four main categories emerged: A delayed care meeting; The experience of well-being is affected by health care; A changed existence and the importance of meaningful relationships. Conclusion: The essay demonstrates that women with myocardial infarction experience a daily suffering connected to their illness. Women feel that the disease limits their daily lives and affects their life situation. The importance of having social contacts and professional support becomes central to improve recovery.

  • Karlsson, Evelina
    et al.
    University of Skövde, School of Health Sciences.
    Lundqvist, Petra
    University of Skövde, School of Health Sciences.
    Föräldrars erfarenheter av sitt barns sista tid i obotlig cancersjukdom - En studie baserad på självbiografier2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: When a child gets sick in incurable cancer, parents become caregivers. They have the right to get information to make decisions and participate in their child’s care. Aim: To describe parents’ experience of their child’s last time in incurable cancer. Method: A narrative method with a qualitative approach was used to analyze four biographies. Results: The analysis resulted in two main themes: Being a parent to a child with incurable cancer and When life changes direction. The result shows that the lifeworld changed and the parenting role was combined with a caregiving role. Discussion: Parents in their caregiving role is in need of information to make decisions related to the child’s care. Parents are affected by suffering during the child’s disease, which means that they may also be in need of care. The nurse has a central role in the care when it comes to information and treatments, but they also need to support the family and guide the parents towards the knowledge that the child is going to die of their disease. Conclusion: The nurse needs to work with a family-centered approach because the parents needs support to fulfill the caregiving role. The nurse also need to have good knowledge about palliative care and be inserted in the child’s care to give good care.

  • Berglund Riikola, Caroline
    et al.
    University of Skövde, School of Health Sciences.
    Fors, Linda
    University of Skövde, School of Health Sciences.
    Att vara patient på svensk akutmottagning – En litteraturöversikt2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: Patient visits at Swedish emergency departments have decreased, but waitingtimes has increased. The triage system is used by nurses to prioritize patients based on their health background and symptoms. A good care environment, regular communication, information, increased participation and person-centered care can reduce the incidence of caregiving for patients who have sought care at Swedish emergency departments. Aim: The aim of this study was to illustrate what it is like to be a patient under waiting time at a Swedish emergency department. Method: This study is a literature review based on ten scientific articles with a qualitative method. Results: Three main categories of meeting with the nurse, factors affecting the experience, consequences of inadequate care. Six subcategories of positive experiences, negative experiences, the impact of the care environment, basic needs, exposure and vulnerability and situation is accepted. Discussion: In the discussion, the authors emphasize patients’ experiences from the emergency department. It was discussed around three concepts person-centered care, caregiving and participation. Conclusion: It emerged that when basic needs were met, information was provided and when the nurse gave confirmation, participation increased, and care sufferers could be prevented.

  • Aspsjö, Jenny
    et al.
    University of Skövde, School of Health Sciences.
    Söderqvist, Therese
    University of Skövde, School of Health Sciences.
    När stress orsakar lidande för sjuksköterskor: En litteraturöversikt om arbetsmiljöns inverkan på psykisk ohälsa2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: The most common cause of sick leave in Sweden is stress related to mental illness. Nurses work involves close contact with people and can be complex and unpredictable. Nurses are a professional group that experiences stress related to the work environment. A stress reaction should normally be for a short period of time, but when it occurs for longer periods, the body's health risks being adversely affected. Stress force people to perform above their normal ability and overperforming adversely affects the body and can lead to mental illness. Purpose: To elucidate nurses' experiences about stressors in the work environment can lead to mental illness. Method: A qualitative litteratured based study was used where eleven scientific articles were analyzed according to Friberg's method. Results: The study highlights seven identified stressors that nurses experience in the work environment that can lead to mental illness. Conclusion: Various stressors that nurses experience are created by the organisation and the working group.

  • Kristensen, Lars
    University of Skövde, School of Informatics. University of Skövde, Informatics Research Environment.
    Evgeniia Iatskina and Alena Rubinshtein: It’s Not Forever (Eto ne navsegda, 2019)2020In: KinoKultura, ISSN 1478-6567, no 68Article, book review (Other (popular science, discussion, etc.))
  • Låstberg, Elias
    et al.
    University of Skövde, School of Health Sciences.
    Wik, Dennis
    University of Skövde, School of Health Sciences.
    Vuxna personers upplevelser av att leva med diabetes typ 2: en litteraturbaserad studie2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: Diabetes typ 2 är en folksjukdom med en stigande prevalens. Sjukdomen kännetecknas av hyperglykemi och sena sjukdomskomplikationer kostar sjukvården stora summor pengar. För att behandla sjukdomen rekommenderas patienter ändra livsstilar och behöver både socialt och professionellt stöd för att genomföra det. Syfte: Att beskriva vuxna personers upplevelse av att leva med diabetes typ 2. Metod: Litteraturbaserad metod för att bidra till evidensbaserad omvårdnad med grund i analys av kvalitativ forskning. Resultat: Ur analysen framträdde två huvudkategorier. Acceptera situationen och livet efter diagnos med fem underkategorier. Slutsats: Att göra förändringar som är hållbara är svåra för personer med diabetes typ 2. Det finns också en skillnad i motivation och vilja till förändring mellan de personer som upplever symtom och de som är symtomlösa. Att stödjas vid förändring är fördelaktigt för processen, vilket stöd personen har tillgång till, och behov av, bör undersökas.

  • Lundahl, Hanna
    University of Skövde, School of Health Sciences.
    Patienters upplevelser av postoperativ vård efter stomioperation: en litteraturöversikt2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: I Sverige lever ca 43 000 patienter med stomi. Stomin påverkar patienter både kroppsligt och psykosocialt. Sjuksköterskan behöver förstå upplevelser hos patienter med stomi för att bedriva personcentrerad vård. Syfte: Att undersöka patienters upplevelse av vård på sjukhus efter stomioperation. Metod: Kvalitativ litteraturöversikt, tematisk analys.Resultat: Tre teman identifierades: 1. Vårdrelationens betydelse 2. En begränsad autonomioch 3. Självförtroende genom lärande. Subteman var 1. Att mötas av öppenhet, kompetens och kontinuitet; Att mötas av kunskapsbrist, inkonsekvens och bristande kontinuitet 2. Attinte vara prioriterad, känslor av beroende; Att förlora kontrollen, känslor av objektifiering 3. Att lära sig egenvård; Att få stöd och information. Konklusion: Vårdpersonalensbemötande påverkar patienters tillit, känslor av autonomi och självförtroende. Negativaupplevelser som begränsad autonomi, maktlöshet och ovisshet skapade lidande hos patienter. Kliniska implikationer: Studien belyser patienters upplevelser av vård på sjukhus efter stomioperation. Sjuksköterskor ges här ökad kunskap om och förståelse för de komplexa fysiska och psykosociala upplevelserna vid stomi för att kunna ge personcentrerad vård med respekt för patientens autonomi och värdighet.

  • Gill, Karin
    et al.
    University of Skövde, School of Health Sciences.
    Richardsson, Jenny
    University of Skövde, School of Health Sciences.
    Hur intensitetsnivån av fysisk aktivitet påverkar hälsan: Sjuksköterskans hälsofrämjande arbete vid metabola syndromet2020Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: Metabola syndromet innebär fysiologiska riskfaktorer som bukfetma och högt blodtryck vilket ger en förhöjd risk att drabbas av kardiovaskulära sjukdomar och diabetes typ 2. Tillståndet ökar globalt och leder till stora hälsoproblem, med fysisk aktivitet kan riskerna förminskas. Sjuksköterskans hälsofrämjande arbete är viktigt, genom att ge stöd och motivation till patienter med metabola syndromet kan hälsan och välbefinnandet öka. För att ge evidensbaserade råd krävs forskning om vilken intensitet fysisk aktivitet ska genomföras med för att uppnå önskat resultat. Syfte: Att kartlägga hur intensiteten av fysisk aktivitet påverkar hälsan hos personer med eller med risk för metabola syndromet. Metod: En litteraturöversikt har gjorts med sammanställning av elva kvantitativa artiklar. Resultat: Resultatet presenteras utifrån teman och underteman som innehåller både text och tabeller. Nyckelfynden är att lågintensiv fysisk aktivitet ger förbättrade resultat på faktorer som påverkar metabola syndromet om patienten tidigare varit stillasittande. Om patienten inte är stillasittande syns ett samband mellan intensitetsnivå och metabola syndromet. Desto högre intensitet som den fysiska aktiviteten genomförs med desto bättre resultat på faktorer som påverkar metabola syndromet. Konklusion: Utifrån kartläggningen som gjorts kan sjuksköterskan ge individuella rekommendationer om intensitetsnivå för fysisk aktivitet till patienter med eller med risk för metabola syndromet.

  • Shi, Lei
    et al.
    Systems and Synthetic Biology Division, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
    Derouiche, Abderahmane
    Systems and Synthetic Biology Division, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
    Pandit, Santosh
    Systems and Synthetic Biology Division, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
    Rahimi, Shadi
    Systems and Synthetic Biology Division, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
    Kalantari, Aida
    Systems and Synthetic Biology Division, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
    Futo, Momir
    Laboratory of Evolutionary Genetics, Division of Molecular Biology, Ruđer Bošković Institute, Zagreb, Croatia.
    Ravikumar, Vaishnavi
    The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
    Jers, Carsten
    The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
    Mokkapati, Venkata R.S.S.
    Systems and Synthetic Biology Division, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
    Vlahoviček, Kristian
    University of Skövde, School of Bioscience. University of Skövde, Systems Biology Research Environment. Bioinformatics group, Division of Molecular Biology, Department of Biology, Faculty of Science, University of Zagreb, Croatia.
    Mijakovic, Ivan
    Systems and Synthetic Biology Division, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden / The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
    Evolutionary Analysis of the Bacillus subtilis Genome Reveals New Genes Involved in Sporulation2020In: Molecular biology and evolution, ISSN 0737-4038, E-ISSN 1537-1719Article in journal (Refereed)
    Abstract [en]

    Bacilli can form dormant, highly resistant, and metabolically inactive spores to cope with extreme environmental challenges. In this study, we examined the evolutionary age of Bacillus subtilis sporulation genes using the approach known as genomic phylostratigraphy. We found that B. subtilis sporulation genes cluster in several groups that emerged at distant evolutionary time-points, suggesting that the sporulation process underwent several stages of expansion. Next, we asked whether such evolutionary stratification of the genome could be used to predict involvement in sporulation of presently uncharacterized genes (y-genes). We individually inactivated a representative sample of uncharacterized genes that arose during the same evolutionary periods as the known sporulation genes and tested the resulting strains for sporulation phenotypes. Sporulation was significantly affected in 16 out of 37 (43%) tested strains. In addition to expanding the knowledge base on B. subtilis sporulation, our findings suggest that evolutionary age could be used to help with genome mining.

  • Maivorsdotter, Ninitha
    et al.
    University of Skövde, School of Health Sciences. University of Skövde, Digital Health Research (DHEAR).
    Andersson, Joacim
    Örebro University, Örebro, Sweden.
    Health as Experience: Exploring Health in Daily Life Drawing From the Work of Aaron Antonovsky and John Dewey2020In: Qualitative Health Research, ISSN 1049-7323, E-ISSN 1552-7557Article in journal (Refereed)
    Abstract [en]

    Research has pursued salutogenic and narrative approaches to deal with questions about how everyday settings are constitutive for different health practices. Healthy behavior is not a distinguishable action, but a chain of activities, often embedded in other social practices. In this article, we have endeavored to describe such a chain of activities guided by the salutogenic claim of exploring the good living argued by McCuaig and Quennerstedt. We use biographical material written by Karl Ove Knausgaard who has created a life story entitled My Struggle. The novel is selected upon an approach influenced by Brinkmann who stresses that literature can be seen as a qualitative social inquiry in which the novelist is an expert in transforming personal life experiences into common human expressions of life. The study illustrates how research with a broader notion of health can convey experiences of health, thereby complementing (and sometimes challenging) public health evidence.

  • Ahmad, Ansar
    University of Skövde, School of Bioscience.
    Evaluation of pipelines for analysis of next-generation sequencing data from CRISPR experiments2019Independent thesis Advanced level (degree of Master (One Year)), 20 credits / 30 HE creditsStudent thesis
  • Lycke, Maria
    et al.
    Department of Obstetrics and Gynecology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.
    Ulfenborg, Benjamin
    University of Skövde, School of Bioscience. University of Skövde, Systems Biology Research Environment.
    Kristjansdottir, Björg
    Department of Obstetrics and Gynecology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.
    Sundfeldt, Karin
    Department of Obstetrics and Gynecology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.
    Increased Diagnostic Accuracy of Adnexal Tumors with A Combination of Established Algorithms and Biomarkers2020In: Journal of clinical medicine, ISSN 2077-0383, Vol. 9, no 2, article id E299Article in journal (Refereed)
    Abstract [en]

    Ovarian cancer is the most lethal gynecologic cancer. Pre-diagnostic testing lacks sensitivity and specificity, and surgery is often the only way to secure the diagnosis. Exploring new biomarkers is of great importance, but the rationale of combining validated well-established biomarkers and algorithms could be a more effective way forward. We hypothesized that we can improve differential diagnostics and reduce false positives by combining (a) risk of malignancy index (RMI) with serum HE4, (b) risk of ovarian malignancy algorithm (ROMA) with a transvaginal ultrasound score or (c) adding HE4 to CA125 in a simple algorithm. With logistic regression modeling, new algorithms were explored and validated using leave-one-out cross validation. The analyses were performed in an existing cohort prospectively collected prior to surgery, 2013-2016. A total of 445 benign tumors and 135 ovarian cancers were included. All presented models improved specificity at cut-off compared to the original algorithm, and goodness of fit was significant (p < 0.001). Our findings confirm that HE4 is a marker that improves specificity without hampering sensitivity or diagnostic accuracy in adnexal tumors. We provide in this study "easy-to-use" algorithms that could aid in the triage of women to the most appropriate level of care when presenting with an unknown ovarian cyst or suspicious ovarian cancer.

  • Iglesia, Iris
    et al.
    Growth, Exercise, Nutrition and Development (GENUD) Research Group, University of Zaragoza, 50009 Zaragoza, Spain / Instituto Agroalimentario de Aragón (IA2), 50013, Zaragoza, Spain / Instituto de Investigación Sanitaria Aragón (IIS Aragón); 50009 Zaragoza, Spain / Red de Salud Materno-infantil y del Desarrollo (SAMID), Instituto de Salud Carlos III, Madrid, 50009 Zaragoza, Spain.
    Intemann, Timm
    Leibniz Institute for Prevention Research and Epidemiology—BIPS, 28359 Bremen, Germany / Institute of Statistics, Bremen University, 28359 Bremen, Germany.
    De Miguel-Etayo, Pilar
    Growth, Exercise, Nutrition and Development (GENUD) Research Group, University of Zaragoza, 50009 Zaragoza, Spain / Instituto Agroalimentario de Aragón (IA2), 50013, Zaragoza, Spain / Instituto de Investigación Sanitaria Aragón (IIS Aragón); 50009 Zaragoza, Spain / Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, 28029 Madrid, Spain.
    Pala, Valeria
    Epidemiology and Prevention Unit, Department of Preventive & Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
    Hebestreit, Antje
    Leibniz Institute for Prevention Research and Epidemiology—BIPS, 28359 Bremen, Germany.
    Wolters, Maike
    Leibniz Institute for Prevention Research and Epidemiology—BIPS, 28359 Bremen, Germany.
    Russo, Paola
    Epidemology & Population Genetics, Institute of Food Sciences, National Research Council, 83100 Avellino, Italy.
    Veidebaum, Toomas
    Department of Chronic Diseases, National Institute for Health Development, 11619 Tallinn, Estonia.
    Papoutsou, Stalo
    Research and Education Institute of Child Health, 2018 Strovolos, Cyprus.
    Nagy, Peter
    Department of Pediatrics, University of Pécs, 7622 Pécs, Hungary.
    Eiben, Gabriele
    University of Skövde, School of Health Sciences. University of Skövde, Digital Health Research (DHEAR). Department of Public Health and Community Medicine, University of Gothenburg, 405 30 Gothenburg, Sweden.
    Rise, Patrizia
    Department of Pharmacological Sciences, University of Milan, 20122 Milan, Italy.
    De Henauw, Stefaan
    Department of Public Health, Ghent University, 9000 Ghent, Belgium.
    Moreno, Luis A.
    Growth, Exercise, Nutrition and Development (GENUD) Research Group, University of Zaragoza, 50009 Zaragoza, Spain / Instituto Agroalimentario de Aragón (IA2), 50013, Zaragoza, Spain / Instituto de Investigación Sanitaria Aragón (IIS Aragón); 50009 Zaragoza, Spain / Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, 28029 Madrid, Spain.
    Dairy consumption at snack meal occasions and the overall quality of diet during childhood: Prospective and cross-sectional analyses from the idefics/i.family cohort2020In: Nutrients, ISSN 2072-6643, E-ISSN 2072-6643, Vol. 12, no 3, article id 642Article in journal (Refereed)
    Abstract [en]

    There is scarce information on the influence of dairy consumption between main meals on the overall diet quality through childhood, constituting the main aim of this research. From the Identification and prevention of Dietary-and lifestyle induced health EFfects In Children and infantS (IDEFICS) study, and based on the data availability in each period due to drop outs, 8807 children aged 2 to 9.9 years from eight European countries at baseline (T0: 2007–2008); 5085 children after two years (T1); and 1991 after four years (T3), were included in these analyses. Dietary intake and the Diet Quality Index (DQI) were assessed by two 24 hours dietary recalls (24-HDR) and food frequency questionnaire. Consumption of milk and yogurt (p = 0.04) and cheese (p < 0.001) at snack meal occasions was associated with higher DQI scores in T0; milk and yogurt (p < 0.001), and cheese (p < 0.001) in T1; and cheese (p = 0.05) in T3. Consumers of milk (p = 0.02), yogurt (p < 0.001), or cheese (p < 0.001) throughout T0 and T1 at all snack moments had significantly higher scores of DQI compared to non-consumers. This was also observed with the consumption of cheese between T1 and T3 (p = 0.03). Consumption of dairy products at snack moments through childhood is associated with a better overall diet quality, being a good strategy to improve it in this period. 

  • Ghosheh, Nidal
    et al.
    University of Skövde, School of Bioscience. University of Skövde, Systems Biology Research Environment.
    Küppers-Munther, Barbara
    Takara Bio Europe AB, Gothenburg, Sweden.
    Asplund, Annika
    Takara Bio Europe AB, Gothenburg, Sweden.
    Andersson, Christian X.
    Takara Bio Europe AB, Gothenburg, Sweden.
    Björquist, Petter
    VeriGraft AB, Gothenburg, Sweden.
    Andersson, Tommy B.
    Cardiovascular Renal and Metabolism, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Mölndal, Sweden / Department of Physiology and Pharmacology, Section of Pharmacogenetics, Karolinska Institutet, Stockholm, Sweden.
    Carén, Helena
    Sahlgrenska Cancer Center, Department of Pathology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden.
    Simonsson, Stina
    Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden.
    Sartipy, Peter
    University of Skövde, School of Bioscience. University of Skövde, Systems Biology Research Environment. Late Stage Cardiovascular, Renal, and Metabolism, R&D BioPharmaceuticals, AstraZeneca, Mölndal, Sweden.
    Synnergren, Jane
    University of Skövde, School of Bioscience. University of Skövde, Systems Biology Research Environment.
    Human Pluripotent Stem Cell-Derived Hepatocytes Show Higher Transcriptional Correlation with Adult Liver Tissue than with Fetal Liver Tissue2020In: ACS Omega, ISSN 2470-1343, Vol. 5, no 10, p. 4816-4827Article in journal (Refereed)
    Abstract [en]

    Human pluripotent stem cell-derived hepatocytes (hPSC-HEP) display many properties of mature hepatocytes, including expression of important genes of the drug metabolizing machinery, glycogen storage, and production of multiple serum proteins. To this date, hPSC-HEP do not, however, fully recapitulate the complete functionality of in vivo mature hepatocytes. In this study, we applied versatile bioinformatic algorithms, including functional annotation and pathway enrichment analyses, transcription factor binding-site enrichment, and similarity and correlation analyses, to datasets collected from different stages during hPSC-HEP differentiation and compared these to developmental stages and tissues from fetal and adult human liver. Our results demonstrate a high level of similarity between the in vitro differentiation of hPSC-HEP and in vivo hepatogenesis. Importantly, the transcriptional correlation of hPSC-HEP with adult liver (AL) tissues was higher than with fetal liver (FL) tissues (0.83 and 0.70, respectively). Functional data revealed mature features of hPSC-HEP including cytochrome P450 enzymes activities and albumin secretion. Moreover, hPSC-HEP showed expression of many genes involved in drug absorption, distribution, metabolism, and excretion. Despite the high similarities observed, we identified differences of specific pathways and regulatory players by analyzing the gene expression between hPSC-HEP and AL. These findings will aid future intervention and improvement of in vitro hepatocyte differentiation protocol in order to generate hepatocytes displaying the complete functionality of mature hepatocytes. Finally, on the transcriptional level, our results show stronger correlation and higher similarity of hPSC-HEP to AL than to FL. In addition, potential targets for further functional improvement of hPSC-HEP were also identified. 

  • Gwozdz, Wencke
    et al.
    Faculty of Agricultural Sciences, Nutritional Sciences and Environmental Management, Justus-Liebig-Universität Gießen, Gießen, Germany / Department of Management, Society, and Communication, CBS Sustainability, Copenhagen Business School, Frederiksberg, Denmark.
    Reisch, Lucia A.
    Department of Management, Society, and Communication, CBS Sustainability, Copenhagen Business School, Frederiksberg, Denmark.
    Eiben, Gabriele
    University of Skövde, School of Health Sciences. University of Skövde, Digital Health Research (DHEAR).
    Hunsberger, Monica L.
    Department of Public Health and Community Medicine, The Sahlgrenska Academy, University of Gothenburg, Arvid Wallgrens Backe, Gothenburg, Sweden.
    Konstabel, Kenn
    Department of Chronic Diseases, National Institute for Health Development, Tallinn, Estonia.
    Kovacs, Eva
    Department of Pediatrics, Medical School, University of Pécs, H-7622 Pécs, Hungary.
    Luszczki, Edyta
    Medical Faculty, University of Rzeszów, Rzeszów, Poland.
    Mazur, Artur
    Medical Faculty, University of Rzeszów, ul.Warszawska 26 a, Rzeszów, Poland.
    Mendl, E.
    Department of Pediatrics, Medical School, University of Pécs, H-7622 Pécs, Hungary.
    Saamel, M.
    Department of Surveillance and Evaluation, National Institute for Health Development,Tallinn, Estonia.
    Wolters, Maike
    Leibniz Institute for Prevention Research and Epidemiology – BIPS, Bremen, Germany.
    The effect of smileys as motivational incentives on children's fruit and vegetable choice, consumption and waste: A field experiment in schools in five European countries2020In: Food Policy, ISSN 0306-9192, E-ISSN 1873-5657, article id 101852Article in journal (Refereed)
    Abstract [en]

    To assess whether smiley stamps work as a motivational incentive to promote fruit and vegetable eating among children, we conducted a field experiment in ten primary schools in five European countries using one control and one treatment school per country. The six-week experiment was split into three two-week phases before, during and after the smiley was implemented. During the smiley phase, the children received a smiley stamp for choosing a portion of fruits or vegetables. We find an increase attributed to the smiley stamp on children's fruit and vegetable choice and consumption, but also waste. Comparing the effects across countries, we observe significant variations in the smiley effect. This study thus demonstrates, in general, that a low-cost, easy-to-implement incentive such as a smiley stamp has the potential to motivate school children to increase their fruit and vegetable consumption; the study simultaneously underscores the high relevance of context for the effects of incentives. 

  • Strand, Mattias
    et al.
    University of Skövde, School of Engineering Science. University of Skövde, Virtual Engineering Research Environment.
    Syberfeldt, Anna
    University of Skövde, School of Engineering Science. University of Skövde, Virtual Engineering Research Environment.
    Using external data in a BI solution to optimise waste management2020In: Journal of Decision Systems, ISSN 1246-0125, E-ISSN 2116-7052Article in journal (Refereed)
    Abstract [en]

    BI solutions are constantly being developed to support decision-making at various organisational levels. These solutions facilitate the compilation, aggregation and summarisation of large volumes of data. Consequently, the business value created by these systems is increasing as they sustain more and more advanced analytics, ranging from descriptive analytics, to predictive analytics, to prescriptive analytics. However, most organisations work primarily with internal data. Despite many references in the literature to the value hidden in external data, details on how such data can be used are scarce. In this paper, we present the results of an extensive action case study at a public waste management company. The results illustrate how external data from several external data sources, integrated into an up-and-running BI solution, are used jointly to allow for descriptive and predictive analytics, as well as prescriptive analytics. In addition, details of these analytical values are given and related to organisational benefits.

  • Bark, Charlotte
    et al.
    University of Skövde, School of Health Sciences.
    Dahlén, Carl
    University of Skövde, School of Health Sciences.
    Ingen talar om det, men jag gör: Barnmorskors upplevelser av att stödja kvinnors sexuella hälsa i relation till en hysterektomi2020Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: Världshälsoorganisationen beskriver sexualiteten som en central aspekt genom hela livet, det är en del av att vara människa. En hysterektomi innebär att kvinnans livmoder tas bort, vilket kan påverka kvinnans sexuella hälsa. Forskning visar att kvinnor har ett stort behov av stöd vid en hysterektomi. Dock finns en brist i att följa upp och stötta kvinnor i olika frågor angående den sexuella hälsan.Syfte: Barnmorskors upplevelser i att stödja kvinnors sexuella hälsa i relation till en hysterektomi.Metod: En kvalitativ innehållsanalys med induktiv ansats där nio barnmorskor intervjuats.Resultat: Barnmorskors upplevelser i att stötta och samtala med kvinnor i relation till en hysterektomi är viktigt. Vissa kvinnor är mer öppna än andra och det är en utmaning i att kunna ge stöd. Tidsbrist i organisationen ses som ett hinder. Stress och bristen på barnmorskekollegor gör att viktig information till kvinnor om den sexuella hälsan inte ges.Konklusion: En hysterektomi kan påverka kvinnors livskvalitet och samliv. I resultatet framkom att vissa barnmorskor informerar vid behov. En del barnmorskor informerar oavsett om de upplever att kvinnor har behov utav det eller inte. Utgår barnmorskorna utifrån sig själva? Hur kan det påverka vården och vilket stöd kvinnor får i den sexuella hälsan.

  • Sandbreck, Roseli
    University of Skövde, School of Health Sciences.
    Riskfaktorer för att förvärva Meticillinresistenta Staphylococcus aureus (MRSA) i vård och omsorg2019Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Introduktion: Förekomst av meticillinresistenta Staphylococcus aureus (MRSA) är ett folkhälsoproblem som påverkar såväl samhället i stort som hälso- och sjukvården. Incidensen har kraftigt ökat under senaste 15 åren, men förbättrade rutiner avseende basala hygienrutiner har samtidigt gjort att smittspridning inom vård och omsorg minskat. Smittspårning runt fall med MRSA är resurskrävande och patienter som löper störst risk att koloniseras bör prioriteras. Syfte: Att utifrån MRSA-smittspårningar där sekundärfall upptäckts undersöka vilka individberoende riskfaktorer som ökar risken för en patient att koloniseras av MRSA i samband med vård. Metod: Retrospektiv fall-kontroll-studie baserad på smittspårningar utförda i Västra Götaland mellan 2017-01-01 och 2019-09-30 (urval n=62). Fallgrupp (n=21); MRSA-positiva patienter (index- och sekundärfall). Kontrollgrupp (n=41); MRSA-negativa patienter som testats negativt i motsvarande smittspårning. Möjliga riskfaktorer har först undersökts genom univariat analys. Vidare analyser, med multivariat logistisk regression, har därefter utförts för variabler där signifikans för samband med utfallsvariabeln var p<0.10. Resultat: Risken att förvärva MRSA ökade vid förekomst av sår OR 8.02 (95% CI 1.85–34.72; p=0.005), demens OR 4.17 (95% CI 1.21–14.30; p=0.023) eller antibiotikabehandling OR 4.50 (95% CI 1.03–19.62; p=0.045) efter justering för ålder. Atopiskt eksem, infart som penetrerar huden, infart via slemhinna eller mer än en grundsjukdom påvisade inte ökad risk att förvärva MRSA. Multivariat analys visade på ökad risk vid kombinerad förekomst av sår och demens eller samtidig antibiotikabehandling men större urval krävs för generaliserbarhet. Slutsats: Patienter med sår, demens eller pågående antibiotikabehandling löper ökad risk att koloniseras av MRSA.

  • Shahid, Fakhar
    et al.
    Department of General Surgery, Hamad Medical Corporation, Doha, Qatar.
    El Ansari, Walid
    University of Skövde, School of Health Sciences. University of Skövde, Digital Health Research (DHEAR). Department of Surgery, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar / College of Medicine, Qatar University, Doha, Qatar.
    Ben-Gashir, Mohamed
    Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar.
    Abdelaal, Abdelrahman
    Department of General Surgery, Hamad Medical Corporation, Doha, Qatar.
    Laparoscopic hydrocelectomy of the canal of Nuck in adult female: Case report and literature review2020In: International journal of surgery case reports, ISSN 2210-2612, E-ISSN 2210-2612, Vol. 66, p. 338-341, article id S2210-2612(19)30674-1Article in journal (Refereed)
    Abstract [en]

    INTRODUCTION: Among adult females, Hydrocele of Canal of Nuck (HCN) is a very rare condition. The majority of the reported cases of HCN were not conclusively diagnosed until surgery was performed on a suspected inguinal hernia. To the best of our knowledge, this is the first case of laparoscopically operated HCN in adult female in Middle East and North Africa Region, and the fourth such case worldwide.

    PRESENTATION OF CASE: A 36-year-old female presented with a painful small swelling in the right groin of 3 months duration. The swelling extended to the right labia majora while standing, and disappeared when the patient was in prone position. There was no lymph node enlargement, no other masses in the abdomen, and no swelling in the contralateral side. Ultrasonography was undertaken and the patient was admitted electively for laparoscopic exploration and repair of non-complicated right inguinal hernia. She was known to have dyslipidemia on medications. Further history and physical examination were unremarkable. Intraoperatively it was diagnosed to be right-sided HCN which was excised and repaired by mesh fixation using transabdominal preperitoneal (TAPP) approach. Her follow up course was unremarkable.

    CONCLUSIONS: This case expands the clinical and intraoperative potential differential diagnosis of adult female groin masses. Surgeons should consider such cases when they observe such swellings intraoperatively. Laparoscopic TAPP approach in such cases is a superior diagnostic and treatment modality.

  • Helldin, Tove
    et al.
    University of Skövde, School of Informatics. University of Skövde, Informatics Research Environment.
    Bae, Juhee
    University of Skövde, School of Informatics. University of Skövde, Informatics Research Environment.
    Alklind Taylor, Anna-Sofia
    University of Skövde, School of Informatics. University of Skövde, Informatics Research Environment.
    Intelligent User Interfaces: Trends and application areas2019Report (Other academic)
    Abstract [en]

    This report outlines trends and application areas within the research field of intelligent user interfaces(IUIs) from 2010-2018. The purpose of the report is to give an overview of the IUI research area andpoint out particular subfields that have been given attention in the recent years, indicating possible trendsfor future research. Our report indicates that the field of IUIs is very broad, resulting in rather diverseresearch trends within the area. However, general trends could be identified, such as an increasing interest inbetter human-machine decision-making, where strategies for explaining the automatic reasoning are beinginvestigated together with ways of improving the trustworthiness of the systems and their possible adaptationsto individuals’ needs. The report also outlines research on multimodal interactions, adaptivity and humanrobotcollaboration, addressing challenges such as increased human workload, unobtrusiveness, privacy andmultiparty communication.

  • Lundvall, Susanna
    University of Skövde, School of Health Sciences.
    Vattenkvalitet i dentala unitar vid Folktandvården i Region Kronoberg2019Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Introduktion: Den dentala unitens vattenkvalitet är av stor betydelse eftersom patienter och tandvårdspersonal regelbundet utsätts för vatten och aerosoler från uniten. Det komplexa vattenledningssystemet utgör en stark riskfaktor för uppkomst av biofilm som kan härbärgera sjukdomsframkallande bakterier.Syfte: Studien syftar till att undersöka i vilken utsträckning dentala unitar uppfyller kriterierna för mikrobiologisk renhet och om mikroorganismer förekommer som kan utgöra en hälsofara för patienter och personal inom tandvården.Metod: Studien är en kvantitativ tvärsnittstudie med vattenprover tagna från 134 dentala units inom Folktandvården, FTV, Region Kronoberg. Studien är en totalundersökning och resultatet presenterat med deskriptiv statistik.Resultat: 96 % av de undersökta unitarna hade tjänligt vatten enligt gränsvärden för heterotrofa bakterier i dricksvatten (LIVSFS 2017:2). 1 25 % av unitarna växte mögel. Legionella fanns i 15 % av unitarna. Stolar installerade innan år 2011 hade genomgående sämre resultat. 6 % av dessa stolar saknade helt vattenreningssystem.Slutsats: Dentala unitar kan utgöra en riskfaktor för infektioner. Vattenkvaliteten bör kontrolleras regelbundet och vid behov åtgärdas. Regelbundna mikrobiologiska kontroller av vattenledningssystemet av den dentala uniten är nödvändigt för att skydda patienter och tandvårdspersonal från vårdrelaterade infektioner.

  • Eldblom, Hans
    University of Skövde, School of Bioscience.
    The nature of conservatism and liberalism: A cognitive neuroscience perspective2017Independent thesis Basic level (degree of Bachelor), 15 credits / 22,5 HE creditsStudent thesis
    Abstract [en]

    In this essay, the author explores the nature of (1) conservatism and (2) liberalism, through a cognitive neuroscience perspective. Traditionally, political behavior and ideological reasoning have been understood in terms of social forces. Recently however, scholars have begun to approach political psychology through a biological perspective, which might add an important insight to the subject. Here, the author presents a collection of findings regarding the psychological and neurocognitive differences between conservatives and liberals. Conservatives appear to have increased activation in the amygdala in response to threat and increased gray matter volume within the right amygdala and left insula. Liberals on the other hand show increased activation in the anterior cingulate cortex (ACC) when cognitive control is required as well as increased gray matter volume. According to the well-known model of political ideology as motivated social cognition, motivations to reduce uncertainty and threat are positively correlated with conservatism and negatively correlated with liberalism. This model is consistent with the findings which suggest that conservatives recruit the amygdala more in response to threat, while liberals recruit the ACC in response to cognitive control. Since applying cognitive neuroscience to political ideology is in its early stages, the conclusions in this essay should be considered as tentative.